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Association of Sleep Duration with All- And Major-Cause Mortality among Adults in Japan, China, Singapore, and Korea

Importance: The association between long sleep duration and mortality appears stronger in East Asian populations than in North American or European populations. Objectives: To assess the sex-specific association between sleep duration and all-cause and major-cause mortality in a pooled longitudinal cohort and to stratify the association by age and body mass index. Design, Setting, and Participants

Dynamics of Mycobacterium tuberculosis-Specific and Nonspecific Immune Responses in Women with Tuberculosis Infection during Pregnancy

The immune control of tuberculosis (TB) infection could be influenced by pregnancy. To elucidate this, we longitudinally characterized Mycobacterium tuberculosis (Mtb)-specific and nonspecific immune responses in women during pregnancy and postpartum. HIV-uninfected women without past or current active TB, and with blood samples available from the 1st/2nd trimester, 3rd trimester, and 9 months pos

Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary Disease : The BEAMS Randomized Clinical Trial

IMPORTANCE: Chronic breathlessness is common in people with chronic obstructive pulmonary disease (COPD). Regular, low-dose, extended-release morphine may relieve breathlessness, but evidence about its efficacy and dosing is needed.OBJECTIVE: To determine the effect of different doses of extended-release morphine on worst breathlessness in people with COPD after 1 week of treatment.DESIGN, SETTING

Plasma and cerebrospinal fluid neurofilament light concentrations reflect neuronal damage in systemic lupus Erythematosus

BACKGROUND: Neuronal damage in systemic lupus erythematosus (SLE) is common, but the extent and mechanisms are unclear. Neurofilament light (NfL) concentrations rise in plasma and cerebrospinal fluid (CSF) during neuronal damage in various neurological disorders. In this cross-sectional study, plasma and CSF concentrations of NfL were explored as a marker of neuronal damage in SLE.METHODS: Seventy

Mesenchymal heterogeneity in the adult human lung

The human lung is a complex tissue consisting of a heterogeneous mix of different structures and cells, each which a specific role that together contribute to the primary function of the organ: the gas exchange. Different mesenchymal cells populate the interstitial areas around airways and blood vessels and form the connective tissue together with the extracellular matrix. Fibroblasts constitute o

Blood- and tumor-based analyses for improved prognostics in lung cancer

Lung cancer is a common cancer type associated with poor prognosis. Even in the group of patients with earlystage tumors, for which curative treatment is possible, lung cancer recurrence is frequent. The aim of this thesis was to investigate the potential prognostic role of mutations in tumor specimens, blood-based proteins and circulating tumor DNA.In study I, we performed EGFR mutation detection

Interleukin-1 receptor antagonist (IL-1Ra) is more effective in suppressing cytokine-induced catabolism in cartilage-synovium co-culture than in cartilage monoculture

Background: Most in vitro studies of potential osteoarthritis (OA) therapies have used cartilage monocultures, even though synovium is a key player in mediating joint inflammation and, thereby, cartilage degeneration. In the case of interleukin-1 (IL-1) inhibition using its receptor antagonist (IL-1Ra), like chondrocytes, synoviocytes also express IL-1 receptors that influence intra-articular IL-1

Older people's occupations. A life with and without work. : A life with and without work

Introduction: The demographic changes with population ageing and a rapidly growing share of very old peoplewill put an increasing pressure on the health and social care system. In order to both restrict early retirement and force people to extend their working life reforms are changing pension systems in many European countries. Besides that older people have to extend their working life it is imp

Discriminative accuracy of [18F]flortaucipir positron emission tomography for Alzheimer disease vs other neurodegenerative disorders

IMPORTANCE The positron emission tomography (PET) tracer [18F]flortaucipir allows in vivo quantification of paired helical filament tau, a core neuropathological feature of Alzheimer disease (AD), but its diagnostic utility is unclear. OBJECTIVE To examine the discriminative accuracy of [18F]flortaucipir for AD vs non-AD neurodegenerative disorders. DESIGN, SETTING, AND PARTICIPANTS In this cross-

Övervakning av fåglarnas populationsutveckling : Årsrapport för 2017

I denna rapport redovisas populationstrender för 208 svenska fågelarter för olika långa tidsperioder. Fåglarna har räknats vinter, vår och sommar enligt strikt standardiserade metoder. Sommarrespektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan 1996) men täcker hela Sverige på ett representativt sätt. Nattaktiva fåglar harWe present the results of the Swedish Bird Survey, run by the Department of Biology, Lund University, as a part of the National Monitoring Programme of the Swedish Environmental Protection Agency. The results for 2017 include data from: 575 winter point counts in 2016/2017 (42nd winter), of which 284 were carried out during the Christmas/New Year count, 223 summer point count routes (43rd year) an

Towards sustainable water use in industry: a case study of the oil refinery industry in Kazakhstan

The concept of “Sustainable water use” (SWU) aims to assure three pillars of sustainability related to the water sector: the social, environmental, and economical. Industrial development, especially in developing countries, requires an adequate response, as industrial activities are recognized as one of the major sources of water pollution, what leads to deterioration of environmental safety and w

Neoadjuvant Trastuzumab, Pertuzumab, and Docetaxel vs Trastuzumab Emtansine in Patients with ERBB2-Positive Breast Cancer : A Phase 2 Randomized Clinical Trial

Importance: Trastuzumab emtansine (T-DM1) is presently approved for treatment of advanced breast cancer and after incomplete response to neoadjuvant therapy, but the potential of T-DM1 as monotherapy is so far unknown. Objective: To assess pathologic complete response (pCR) to standard neoadjuvant therapy of combination docetaxel, trastuzumab, and pertuzumab (DTP) vs T-DM1 monotherapy in patients

Helicobacter pylori screening in clinical routine during hospitalization for acute myocardial infarction

Background: Potent antithrombotic therapy has significantly improved prognosis for patients with acute myocardial infarction (AMI), however, at a price of increased bleeding risk. Chronic gastric infection with Helicobacter pylori (Hp) commonly causes upper gastrointestinal bleeding and is proposed as a risk factor for subsequent bleeding post AMI. The prevalence of active Hp in a current AMI popu

The immune microenvironment of colorectal cancer - Relationship with survival, sidedness, and pre-diagnostic anthropometry

Colorectal cancer (CRC) is the third most common cancer worldwide. Increasing evidence suggests that CRC should be considered a heterogeneous disease, with multiple differences between proximal and distal tumours. The immune system may, depending on the context, promote or inhibit tumour growth, and different immune cell subsets have been found to be associated with impaired or improved prognosis

Lunds-universitets-magasin-1-2014

Ny modell för pedagogisk utbildning Kamp för studentbostäder lönade sig Humanvetare på plats i Bryssel Lunds universitets magasin | nr 1 | 2014 en KOntinent med POtentiaL Utblick Afrika 2 LUM nr 1 | 2014 LUM nr 1 | 2014 3 – den allmänna uppfattningen om kvinnors ställning verkar vara att den ser likadan ut i de flesta arabiska och muslimska länder. men i tunisien är det mycket som är annorlunda, s

https://www.lu.se/sites/www.lu.se/files/lunds-universitets-magasin-1-2014.pdf - 2026-06-03

Designwastedigntiy eng 0

DESIGN WASTE & DIGNITY This book can not be sold because it was supported by CNPq - National Council for Scientific and Technological Development. The authors authorize the reproduction and total or partial disclosure this work, by any conventional or electronic means, for study and research, provided the source is acknowledged and having the publisher permission. contato@editoraolhares.com.br Edi

https://www.ses.lu.se/sites/ses.lu.se/files/designwastedigntiy_eng_0.pdf - 2026-06-03

ASP Matematisk Statistik 2020-989

Allmän studieplan för forskarutbildning Sida 1 av 11 Fakultetsstyrelsen STUDIEPLAN Diarienummer U 2020/989 Datum 2020-12-16 Allmän studieplan för forskarutbildning i ämnet matematisk statistik, NAMAST01 Studieplanen är fastställd av fakultetsstyrelsen 2020-12-16 och gäller för forskarstuderande antagna från och med 2021-01-01. Studieplanen bygger på Högskoleförordningens (1993:100) 6 kap. §§ 1–11,

https://www.naturvetenskap.lu.se/sites/naturvetenskap.lu.se/files/2024-05/ASP%20Matematisk%20statistik%202020-989.pdf - 2026-06-03

ASP Numerisk Analys 2020-989

Allmän studieplan för forskarutbildning Sida 1 av 10 Fakultetsstyrelsen STUDIEPLAN Diarienummer U 2020/989 Datum 2020-12-16 Allmän studieplan för forskarutbildning i ämnet numerisk analys, NANUMA02 Studieplanen är fastställd av fakultetsstyrelsen 2020-12-16 och gäller för forskarstuderande antagna från och med 2021-01-01. Studieplanen bygger på Högskoleförordningens (1993:100) 6 kap. §§ 1–11, 25–3

https://www.naturvetenskap.lu.se/sites/naturvetenskap.lu.se/files/2024-05/ASP%20Numerisk%20analys%202020-989.pdf - 2026-06-03

Investigating CSF flow in patients with idiopathic normal pressure hydrocephalus using phase-contrast 7T MRI

Idiopatisk normaltryckshydrocephalus (iNPH) är en neurologisk sjukdom som påverkar hjärnans vätskecirkulation och kan leda till symtom som gång- och balanssvårigheter, kognitiv nedsättning och urininkontinens. Sjukdomen drabbar omkring 1.5 % av 70-åringar, och prevalensen ökar med åldern. Det är en svårdiagnostiserad sjukdom där hjärnvätska (CSF) ansamlas i hjärnans hålrum, vilket påverkar hjärnanIntroduction: Idiopathic normal pressure hydrocephalus (iNPH) is a treatable but largely underdiagnosed neurological condition affecting the elderly population. It is characterised by gait and cognitive impairment, as well as urinary incontinence. For the most part, it is diagnosed via imaging and clinical assessments. Abnormalities in cerebrospinal (CSF) flow in the cerebral aqueduct have been li