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Promising treatment for aggressive childhood cancer

Published 6 October 2020 Karin Hansson and Daniel Bexell. Photo: Åsa Hansdotter A drug has shown great promise in the treatment of neuroblastoma, an aggressive form of childhood cancer. The study was led by researchers at Lund University in Sweden, and is published in the journal Science Translational Medicine. Every year, about 800 children in the US are diagnosed with neuroblastoma, an aggressiv

https://www.tcr.lu.se/article/promising-treatment-aggressive-childhood-cancer - 2025-06-25

Oxygen-sensing mechanisms across eukaryotic kingdoms and their roles in complex multicellularity

Published 16 November 2020 Emma Hammarlund and Sofie Mohlin at TCR, together with two colleagues from Oxford University, have reviewed how oxygen-sensing mechanisms across eukaryotic kingdoms are alike. From a functional perspective, these systems are active at low oxygen and degraded at high, although their scope varies.    2020-11-16_hammarlund_et_al_2020.pdf .

https://www.tcr.lu.se/article/oxygen-sensing-mechanisms-across-eukaryotic-kingdoms-and-their-roles-complex-multicellularity - 2025-06-25

PI:s at TCR receive Cancerfonden grants

Published 18 November 2020  Big congratulations to PI:s Daniel Bexell Novel treatment for high-risk neuroblastoma, Christer Larsson Mechanisms determining breast cancer cell fate upon death receptor stimulation - apoptosis or a change in phenotype, Ramin Massoumi Targeted therapy against metastatic melanoma and Sofie Mohlin An Embryonic Model in the Search for Childhood Cancer Initiation on receiv

https://www.tcr.lu.se/article/pis-tcr-receive-cancerfonden-grants - 2025-06-25

Coming up: LUCC Imaging & nuclear medicine/radiology seminar

By ramin [dot] massoumi [at] med [dot] lu [dot] se (Ramin Massoumi) - published 28 January 2021 SAVE THE DATE for this upcoming event. Dear all, We hope you are all keeping yourselves safe and healthy through this challenging time.We would like to cordially invite you to a digital imaging meeting including short presentations and discussions about existing imaging facilities and the need for devel

https://www.tcr.lu.se/article/coming-lucc-imaging-nuclear-medicineradiology-seminar - 2025-06-25

PI:s at TCR receive Cancerfonden grants

Published 15 November 2021 Cancerfonden logo Big congratulations to PI:s Håkan Axelson Transformation of renal epithelial cells: the nephron and renal cell carcinoma, Anders Bjartell Integration of Biomarkers in Clinical Models for Improved Outcome Prediction and New Therapies in Prostate Cancer, Emma Hammarlund Utilizing the isotopic elemental fingerprint of cancer to understand tumorgenesis and

https://www.tcr.lu.se/article/pis-tcr-receive-cancerfonden-grants-0 - 2025-06-25

New Cancerfonden grants

Published 25 March 2022 Big congratulations to: Alexander Pietras, The irradiated brain tumor microenvironment: Biology and therapeutic tagets, on receiving Senior Investigator Award, and to Paulina Bolivar, in Kristian Pietras group, Integrative single-cell and spatial analyses to reveal micriniche organization in the tumor microenvironment of triple negative breast cancer, on receiving Postdoc g

https://www.tcr.lu.se/article/new-cancerfonden-grants - 2025-06-25

Millions in funding for PI Daniel Bexell

Published 16 December 2019 PI Daniel Bexell has been awarded millions in funding from Åke Wibergs foundation that goes to young PIs in medical research. One of the aims is to find out why some tumors develop resistance to today’s treatment but also to find new treatment strategies. Every year around 20 children in Sweden are diagnosed with Neuroblastoma, most before even turning 5 years of age. It

https://www.tcr.lu.se/article/millions-funding-pi-daniel-bexell - 2025-06-25

The PDGF pathway in breast cancer is linked to tumour aggressiveness, triple-negative subtype and early recurrence

Published 1 June 2018 The platelet-derived growth factor (PDGF) signalling pathway is often dysregulated in cancer and PDGF-receptor expression has been linked to unfavourable prognostic factors in breast cancer (e.g. ER negativity, high Ki67 and high grade). This study aimed to evaluate the expression of PDGFRα, PDGFRβ and ligand PDGF-CC in breast cancer in relation to molecular subtypes and prog

https://www.tcr.lu.se/article/pdgf-pathway-breast-cancer-linked-tumour-aggressiveness-triple-negative-subtype-and-early-recurrence - 2025-06-25

Researchers from TCR receive Barncancerfonden grants

By johanna [dot] verngren [at] med [dot] lu [dot] se (Johanna Verngren) - published 18 January 2023 Big congratulations to  Kazi Uddins group on receiving Barncancerfonden grant for "Utveckling av riktade kombinationsterapi och nya verktyg för att förutspå terapi-resistens" and to Alexander Pietras group on receiving Barncancerfonden grant for "Syrebristberoende måltavlor i barngliom och ponsgliom

https://www.tcr.lu.se/article/researchers-tcr-receive-barncancerfonden-grants - 2025-06-25

Researchers from TCR receive Swedish Research Council grants

By johanna [dot] verngren [at] med [dot] lu [dot] se (Johanna Verngren) - published 29 November 2023 Big congratulations on receiving grants from Swedish Research Council (Vetenskapsrådet, VR):Daniel Bexell, Mekanismer och nya behandlingsstrategier mot resistent neuroblastom, and to...Anders Bjartell, Målriktade behandlingar och biomarkörer vid avancerad prostatacancer, and to...Kristian Pietras,

https://www.tcr.lu.se/article/researchers-tcr-receive-swedish-research-council-grants - 2025-06-25

Researchers from TCR receive Cancerfonden grants

By johanna [dot] verngren [at] med [dot] lu [dot] se (Johanna Verngren) - published 30 November 2023 Big congratulations on receiving Cancerfonden grants:Daniel Bexell, Decoding and Targeting Treatment-Resistant Metastatic Neuroblastoma, an to...Christer Larsson, Induction and consequences of interferon expression in breast cancer cells, and to...Ramin Massoumi, Novel preclinical models for treatm

https://www.tcr.lu.se/article/researchers-tcr-receive-cancerfonden-grants - 2025-06-25

TCR now has two postdoc positions available

By johanna [dot] verngren [at] med [dot] lu [dot] se (Johanna Verngren) - published 30 April 2024 One ERC-funded postdoc position in Molecular Pediatric Oncology lab, led by PI Daniel Bexell. The group is working with neuroblastoma (NB), a severe childhood cancer. The overall aims are to unravel mechanisms leading to metastasis and treatment resistance of NB, and to test compounds targeting aggres

https://www.tcr.lu.se/article/tcr-now-has-two-postdoc-positions-available - 2025-06-25

A Beginner's Guide to Swedish Academia

Published 8 December 2022 The Young Academy of Sweden, an interdisciplinary academy for a selection of the most prominent younger researchers in Sweden, has launched "A Beginner’s Guide to Swedish Academia", a guide for international researchers, to help navigate Swedish academia and remove time-consuming obstacles. The Young Academy of Sweden (YAS) is an independent platform that provides young r

https://www.wcmm.lu.se/article/beginners-guide-swedish-academia - 2025-06-25

A new WCMM doctor!

Published 8 December 2022 The WCMM centre has got yet another new doctor! Roberta Battistella, PhD student in the Lundgaard lab, successfully defended her thesis this month. Roberta Battistella, PhD student in the Lundgaard lab and part of MultiPark, defended her PhD thesis entitled “Methods to study glymphatic system in rodents´ brain during physiological and pathophysiological processes” on the

https://www.wcmm.lu.se/article/new-wcmm-doctor-0 - 2025-06-25

Karin Tran Lundmark receives Heart-Lung Foundation grant of 2.4 million SEK

Published 8 December 2022 Karin Tran Lundmark was awarded funding from the Heart-Lung Foundation for the project "Synchrotron-based imaging to decipher cardiovascular pathobiology". The funding includes 800.000 SEK per year for 3 years. The main purpose of this project is to find novel treatments for pulmonary hypertension. To achieve this, Karins group aims to:  Use synchrotron-based imaging comb

https://www.wcmm.lu.se/article/karin-tran-lundmark-receives-heart-lung-foundation-grant-24-million-sek - 2025-06-25