Fluoxetine (FLX), a P-glycoprotein inhibitor with antimalarial activity, is promising candidate for reversing chloroquine/mefloquine (CQ/MQ) resistance. The Dd2 strain of CQ- and MQ-resistant Plasmodium falciparum was synchronized and assayed with various concentrations of CQ/MQ individually and in combination with FLX or verapamil (VPL). Our results indicated the 50% inhibitory concentration valu

Most reef-building corals live in partnership with so-called zooxanthellae in a mutually dependent way. Zooxanthellae are unicellular algae (dinoflagellates) inside the coral polyps, and by their photosynthesis they contribute to the sustenance of the coral. Corals already existed during the Cambrian period, more than 500 million years ago, bu these were very different from today's reef-building s

The study aimed to find out the influence of sweating on footwear insulation with a thermal foot model. Simultaneously, the influence of applied weight (35 kg), sock and steel toe cap were studied. Water to 3 sweat glands was supplied with a pump at the rate of 10 g/h in total. Four models of boots with steel toe caps were tested. The same models were manufactured also without steel toe. Sweating

This thesis consists of four papers on web performance analysis. In the first paper we investigate the performance of overload control through queue length for two different web server architectures. The simulation result suggests that the benefit of request prioritization is noticeable only when the capacities of the sub-systems match each other. In the second paper we present an M/G/1/K*PS queue

Operatively induced, standardized tibia fractures in 42 10-week-old male rats were fixed with intramedullary nails. 21 of the rats were fed liquid containing 15% ethanol. 5 weeks after inducing the fracture, the rats were killed and the total body bone mineral density (BMD) was analyzed with the DEXA technique, and the mechanical properties of the fractured and the unfractured tibiae as well as th

This report is part of a project that is called Generic hybrid systems. Its objective is to simulate and investigate electric hybrid drive trains. The goal of this work has been to develop combustion engine models that are computer efficient, but still has the potential of giving both qualitative and quantitative results. For instance, if the model is run in a less ideal manner the model will show

An assay for the ability of antioxidants to prevent mutations induced by various oxidants in Salmonella typhimurium TA102 cells was developed. Protection against hydrogen-peroxide-induced mutagenicity was observed for quercetin, caffeic acid, ascorbic acid and dimethyl sulfoxide (used as a solvent for water-insoluble antioxidants). No protective effect was observed for green tea extract (weakly pr

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The aim was to investigate dimensions of caregiving activities among elderly (75+) caregivers based on Nolan's model and to study the dimensions in relation to health-related quality of life (Short Form 12). Responses to a Swedish postal survey (n = 4278, response rate 75-79 years old: 60%; 80-84: 56%; 85-89: 48% and 90+: 42%) showed that 783 persons (18%) were helping another person due to that p

We observe a correspondence between the zero modes of superconformal algebras S'(2,1) and W(4) ([8]) and the Lie superalgebras formed by classical operators appearing in the Kahler and hyper-Kahler geometry.

The Sheinwoodian succession of Gotland comprises the Högklint, Tofta and Hangvar Formations and most of the Slite Group. The succession consists of hierarchically ordered shallow marine depositional cycles, produced by orbitally forced climate changes. During warmer and wetter intervals (climate maxima) more carbonate was produced than during the cooler and dryer climate minima. Higher carbonate p

It is well known that peripherally administered growth hormone (GH) results in decreased body fat mass. However, GH-deficient patients increase their food intake when substituted with GH, suggesting that GH also has an appetite stimulating effect. Transgenic mice with an overexpression of bovine GH in the central nervous system (CNS) were created to investigate the role of GH in CNS. This study sh

Popular Abstract in Swedish Syftet med denna undersökning är att diskutera inlärares signaler om hjälp att uttrycka sig på främmande språk, här franska, signaler som här kallas ?sollicitationer?. Undersökningen handlar om vilken roll dessa spelar för den fortsatta utvecklingen av samtalet med den infödde talaren, närmare bestämt för att utlösa s.k. SPA (Séquences Potentiellement Acquisitionnelles)The aim of this study is to discuss how ?soliciting? (non-native speakers? requests of native speakers for help in how to express themselves in a foreign language) may play a part in the triggering of SPAs (Séquences Potentiellement Acquisitionnelles or ?learning?teaching sequences?). The beneficial effect of SPAs for learning is still controversial, since no correlation has yet been shown between

Seventeen patients with sciatica and isthmic lumbar spondylolisthesis were studied with magnetic resonance (MR) imaging. In 13, myelography was also performed: 5 had dural sac deformation and root sleeve shortening, 2 had deformation with unilateral root sleeve shortening, one had bilateral root sleeve shortening only, and one had sac deformation only. In 4, myelography was normal. On sagittal MR