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Do intensive studies of a foreign language improve associative memory performance?

Formal education has been proposed to shape life-long cognitive development. Studies reporting that gains from cognitive training transfer to untrained tasks suggest direct effects of mental activity on cognitive processing efficiency. However, associative memory practice has not been known to produce transfer effects, which is odd considering that the key neural substrate of associative memory, t

Determination of spin and parity of the Higgs boson in the [Formula: see text] decay channel with the ATLAS detector.

Studies of the spin and parity quantum numbers of the Higgs boson in the [Formula: see text] final state are presented, based on proton-proton collision data collected by the ATLAS detector at the Large Hadron Collider, corresponding to an integrated luminosity of 20.3 fb[Formula: see text] at a centre-of-mass energy of [Formula: see text] TeV. The Standard Model spin-parity [Formula: see text] hy

Manual versus mechanical cardiopulmonary resuscitation. An experimental study in pigs

Background: Optimal manual closed chest compressions are difficult to give. A mechanical compression/ decompression device, named LUCAS, is programmed to give compression according to the latest international guidelines (2005) for cardiopulmonary resuscitation (CPR). The aim of the present study was to compare manual CPR with LUCAS-CPR. Methods: 30 kg pigs were anesthetized and intubated. After a

Resistivity Modelling of Fracture Zones and Horizontal Layers in Bedrock

2D resistivity modelling was done in order to examine the imaging resolution of 4 different configurations for mapping of fracture zones in bedrock. The studied arrays include Dipole-dipole, Gradient, Pole-dipole and Wenner. A variety of geological models were tested and the imaging possibilities and limitations of the different arrays were analysed. Apart from imaging fracture zones with various

Increased health care utilization by survivors of childhood lymphoblastic leukemia is confined to those treated with cranial or total body irradiation: a case cohort study.

Previous studies have indicated that survivors of childhood acute lymphoblastic leukemia (ALL) have an increased morbidity measured in terms of health care utilization. However, earlier studies have several potentially important limitations. To overcome some of these, we investigated hospital contact rates, and predictors thereof, among 5-year survivors of ALL in a population-based setting, and co

The interconnected KIT receptor and Microphthalmia-associated transcription factor axis in melanoma

Popular Abstract in Swedish Den farligaste formen av hudcancer, melanom, uppkommer genom okontrollerad tillväxt av melanocyter som är celler specialiserade i pigmentproduktion. Dessa celler skyddar oss från den farliga UV-strålingen med hjälp av pigment som omvandlar ljusvågor till värme. I Sverige drabbas drygt 2000 personer per år av sjukdomen. Cirka 80-85 % av dessa botas genom kirurgi men hos Melanoma is an aggressive disease that arises from deregulated signaling events in melanocytes. The KIT receptor tyrosine kinase and the Microphthalmia-associated transcription factor (MITF) are two essential components that are required for the normal physiology of melanocyte development and function. Consequently, aberrant activities of these factors are involved in the development of melanoma.

Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors.

Recent findings show that human fibroblasts can be directly programmed into functional neurons without passing via a proliferative stem cell intermediate. These findings open up the possibility of generating subtype-specific neurons of human origin for therapeutic use from fetal cell, from patients themselves, or from matched donors. In this study, we present an improved system for direct neural c

Accounting for one-channel depletion improves missing value imputation in 2-dye microarray data

Abstract in UndeterminedBackground: For 2-dye microarray platforms, some missing values may arise from an un-measurably low RNA expression in one channel only. Information of such "one-channel depletion" is so far not included in algorithms for imputation of missing values.Results: Calculating the mean deviation between imputed values and duplicate controls in five datasets, we show that KNN-based

The determination of plasmin and plasminogen-derived activity in turbid samples from various dairy products using an optimised spectrophotometric method

A spectrophotometric assay for plasmin and plasminogen-derived activity in dairy products was optimised and extended to determine plasmin and plasminogen-derived activity in turbid samples of dairy products. The method was validated by assessing reproducibility, repeatability, level of detection and recovery of plasmin activity in different sample matrices. Plasmin activity in raw milk was not aff

A measurement of the ratio of the W and Z cross sections with exactly one associated jet in pp collisions at root s=7 TeV with ATLAS

The ratio of production cross sections of the W and Z bosons with exactly one associated jet is presented as a function of jet transverse momentum threshold. The measurement has been designed to maximise cancellation of experimental and theoretical uncertainties, and is reported both within a particle-level kinematic range corresponding to the detector acceptance and as a total cross-section ratio

Y5 neuropeptide Y receptor overexpression in mice neither affects anxiety- and depression-like behaviours nor seizures but confers moderate hyperactivity

Neuropeptide Y (NPY) has been implicated in anxiolytic- and antidepressant-like behaviour as well as seizure-suppressant effects in rodents. Although these effects appear to be predominantly mediated via other NPY receptors (Y1 and/or Y2), several studies have also indicated a role for Y5 receptors. Gene therapy using recombinant viral vectors to induce overexpression of NPY, Y1 or Y2 receptors in

Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory function.

The levels of nitric oxide (NO) and various cytokines are known to be increased during sepsis. These signaling molecules could potentially act as regulators and underlie the enhancement of mitochondrial function described in the later phase of sepsis. Therefore, we investigated the correlation between observed changes in platelet mitochondrial respiration and a set of pro- and anti-inflammatory cy