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Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis-inducing factor, cytochrome c and caspase-3 activation in neurons exposed to transient hypoglycemia.
Dagens kommunikationsprogram för svåra för vanliga användare
Farmland prices, structural breaks and panel data
Previous time series evidence has indicated that farmland prices and cash rents are not cointegrated, a finding at odds with the present value model of farmland prices. We argue that this failure to find cointegration may be due to low power of tests and to the presence of structural change representing a shifting risk premium on farmland investments. To accommodate this possibility, we use panel
Enhanced insulin absorption in the rabbit airways and lung by sodium dioctyl sulfosuccinate
The objective of this investigation was to study regional absorption of inhaled insulin together with an enhancer (sodium di-octyl-sulfosuccinate [DOSS]) in the rabbit airways and lung. Insulin was administered with or without DOSS by aerosol inhalation, intratracheal infusion, intranasally, sublingually, and without DOSS intravenously. Blood glucose and plasma levels of insulin were measured duri
Identification of novel proteolytic forms of osteocalcin in human urine
In this study, we report the isolation and characterization of osteocalcin in human urine using mass spectrometry and N-terminal sequencing. Multiple proteolytic forms of osteocalcin were found, which consisted of 16-27 residues from the middle region of the molecule. Several fragments had residue Gly7 at the N-terminus and the most predominant was fragment 7-31. Additional fragments starting from
The G-protein coupled receptor CMKLR1/ChemR23: Studies on gene regulation, receptor ligand activation, and HIV/SIV co-receptor function
Popular Abstract in Swedish För att en organism ska fungera är det nödvändigt att alla de celler som bygger upp organismen kommunicerar med varandra. Denna kommunikation sker genom att speciella proteiner på cellens yta, s.k. receptorer, tar emot signaler från andra celler. G-proteinkopplade receptorer (GPCR) är den vanligaste typen av receptorer. Då en signalmolekyl binder till en GPCR ändrar deIn all higher organisms, there is a need for intercellular communication. G-protein coupled receptors (GPCRs), located on the cell surface, play an important role in this communication. Cells synthesize and release signalling molecules (ligands), which produce a specific response only in those cells that have a receptor for that ligand. The total number of GPCRs is estimated to be around 800 where
Migration of uncemented, long-stem femoral components in revision hip arthroplasty. A 2-8 year clinical follow-up of 45 cases and radiostereometric analysis of 13 cases
We reviewed after 48 (24-90) months the clinical results in 45 cases of revision hip arthroplasties where an uncemented, long-stem femoral prosthesis (BIAS, Zimmer) had been used. A subgroup of 13 cases was followed with radiostereometric analysis (RSA) for 2 years. 3/45 cases had been revised, another 12 had unsatisfactory pain scores. The median Harris score was 69 (26-99). 12/13 stems migrated;
Defense mechanisms and morality: A link between isolation and moralization.
The relationship between morality and perceptual defense mechanisms was studied. Three new scales were constructed to measure different aspects of morality: moralism (the tendency to evaluate everything in terms of right and wrong), conscience (strength of feelings of right and wrong) and reparation (inclination to repair the damage one has caused). Perceptual defense mechanisms were measured with
Effects of ethanol on fatty acid esterification and oxidation in isolated rat hepatocytes
In hepatocytes from fed rats, ethanol significantly increased fatty acid esterification but had little effect on fatty acid oxidation.
Liten blödningsrisk med trombosprofylax vid regionalanestesi visar enkätstudie
LQG Self-Tuners
An analytical model to predict dune erosion due to wave impact
An analytical model is developed to calculate recession distance and eroded volume for coastal dunes during severe storms. The transport relationship used in the model is based on wave impact theory, where individual swash waves hitting the dune face induce the erosion. Combining this relationship with the sediment volume conservation equation describes the response of the dune to high waves and w
Globalization and the capacity of violence to transform social spaces: Some critical points about the Latin America debate
The aim of this study is to try and explain the relationship between violence and the changes taking place in social spaces. Violence, in all its dimensions, has taken a central place in Latin American social life and has become an almost totally private issue. This implies a series of spatial and social transformations in the cities. The new effects of violence influence social and ethnic segrega
Statistical analysis of non-Gaussian environmental loads and responses
The thesis deals mainly with offshore engineering related problems where the dominant source of uncertainty is related to the loading. Loads arise from environmental random processes; e.g. waves, currents and winds. Complex as they are, such processes beg the consideration of randomness whence the need of associating probabilistic models to the engineering problems treated here. Two different typ
Acta ophthalmologica and the net
Rotational Bands in 76Rb
High spin states in 76Rb were investigated via the reaction 40Ca(40Ca,3pn)76Rb at 128 MeV. The level scheme was established from γγ, γγγ and recoil-γ coincidences measured in the EUROGAM I array in combination with the Daresbury recoil separator. The known rotational bands were extended up to the excitation energy Ex≊9.2 MeV and spins Iπ=(21+) and (19-). The band head energies could be fixed by ma
Balanced Scorecard i landsting - erfarenheter från tolv projekt i Region Skåne
Denna rapport sammanfattar och reflekterar över lärdomar från tolv Balanced Scorecard projekt. Rapporten skall i första hand läsas som ett bidrag till diskussionen om relevansen av Balanced Scorecard i utvecklingen av kommunala sektorns styrsystem. Vad som förmedlas är en illustration av och reflektion över styrmodellens förtjänster och till¬korta¬kommanden. Rapporten är ett resultat av ett utvec