The Distinguished Professor programme was created by the Swedish Research Council to allow the most prominent researchers to conduct long-term, ground-breaking research which has great potential for achieving scientific breakthroughs. The Distinguished Professor programme is awarded to at least 2 scientists every second year between 2019-2029 by the Swedish Research Council. It was created to allo

https://www.stemcellcenter.lu.se/article/malin-parmar-awarded-distinguished-professorship-swedish-research-council - 2025-08-21

The career program Wallenberg Academy Fellows is the largest private investment in young researchers in Sweden. It provides the most promising young researchers with long-term resources, giving them excellent opportunities to establish themselves and build up their research groups. Wallenberg Academy Fellows is designed for young researchers and was launched by the Knut and Alice Wallenberg Founda

https://www.stemcellcenter.lu.se/article/daniella-rylander-ottosson-has-been-admitted-wallenberg-academy-fellow - 2025-08-21

The cover of Mikael's thesis is an artistic take on hematopoetic stem cell biology, combining the old and new view of hematopoietic differentiation, with the hematopoietic stem cell highlighted in the centre. Mikael has been investigating the influence of cellular heterogeneity in ontogeny, ageing and leukemia. In this interview, he tells us about his time as a PhD student in the group of Stem Cel

https://www.stemcellcenter.lu.se/article/phd-defence-interview-mikael-sommarin-0 - 2025-08-21

A human midbrain organoid visualised by staining for proteins important during the maturation of dopaminergic neurons. (photo: Alessandro Fiorenzano) In their latest study, published in Nature Communications, the Parmar Lab has established midbrain organoids using silk microfibers as scaffolds, offering a refined in vitro model of human midbrain development. They have studied their silk midbrain o

https://www.stemcellcenter.lu.se/article/human-midbrain-organoids-grown-silk-recapitulate-midbrain-development-and-support-functionally - 2025-08-21

An optimised iPSC-differentiation protocol allowed the authors to study endothelial cells (purple), transitioning cells (pink), and hematopoietic stem-like cells (blue) using scRNA-seq. A UMAP visualise the cells in the shape of a butterfly. In a recent study from the SCC group of Niels-Bjarne Woods and collaborators, they have investigated the metabolic changes accompanying the emergence of blood

https://www.stemcellcenter.lu.se/article/metabolic-switch-during-embryonic-hematopoiesis-major-regulator-lineage-commitment - 2025-08-21

Ludwig Schmiderer has studied how to overcome delivery challenges in stem cell biology with nanotechnology. In this interview, he tells us about his research and generative art. What have you been working with during your PhD studies? At the beginning of my PhD, I was trying to reengineer the CRISPR/Cas9 system to make it work in mitochondria instead of nucleus. The project started off quite well

https://www.stemcellcenter.lu.se/article/phd-defence-interview-ludwig-schmiderer - 2025-08-21

The Nilsson lab performed a genome-wide association study on 13,167 individuals, 18-78 years old, and identified previously unknown regulators of blood HSPC levels. Stem cell transplantation is a cornerstone in the treatment of blood malignancies. In order to succeed, stem cells need to be harvested from a donor. This requires that hematopoietic stem and progenitor cells (HSPC) are mobilized from

https://www.stemcellcenter.lu.se/article/large-scale-genome-wide-association-study-reveals-new-potential-drug-target-blood-stem-cell - 2025-08-21

Principal Investigator, Filipe Pereira. Photo: Kennet Ruona The Pereira research group has previously shown that it is possible to reprogram human skin cells into dendritic cells that strengthen the immune system. However, the efficiency of these reprogrammed cells has been shown to be very low. New studies now indicate that there are ways to increase the efficiency of these reprogrammed cells by

https://www.stemcellcenter.lu.se/article/new-findings-indicate-ways-increase-efficiency-reprogrammed-immune-cells - 2025-08-21

Charlotta Böiers, head of StemTherapy FACS Core Facility research infrastructure, and Mikael Sommarin, research engineer, discuss the results of a 22-colour analysis made on the new FACS device Symphony S6. Photo: Åsa Hansdotter. Anna Fossum, Project Manager at the StemTherapy FACS Core Facility research infrastructure, has been sorting cells with a variety of types of FACS machines for the past 2

https://www.stemcellcenter.lu.se/article/new-addition-lund-stem-cell-center-facs-facility - 2025-08-21

Photo of Dr. Cristian Bellodi and Dr. Sowndarya Muthukumar Researchers from Lund University, building on previous studies, have been working to understand why stem cells are transforming into cancer. Previously they revealed that small RNA molecules, long considered “junk” or degradation byproducts of RNA-sequencing, are emerging as key regulators of important cellular processes, like protein synt

https://www.stemcellcenter.lu.se/article/what-makes-stem-cells-transform-cancer-answer-may-lie-our-rna - 2025-08-21

Photo of Svetlana Soboleva (right) and an image of her PhD thesis cover (left). Svetlana Soboleva is set to defend her Ph.D. thesis on 13 April, 2022. For the past few years her world has revolved around red blood cells, as she has worked to establish methods that allow for the generation of enucleated cells, using immortalized erythroid cell lines, to develop erythrocytes. In short, she’s been wo

https://www.stemcellcenter.lu.se/article/blood-lab-phd-defence-interview-svetlana-soboleva - 2025-08-21

One of the Electrophysiology Core Facilities' rigs in use during an experiment. Photo credit: Johan Persson. This year Lund Stem Cell Center and MultiPark, two strategic research areas based at Lund University, are happy to launch a new joint technical platform in an effort to ensure easy access to high quality core electrophysiology techniques and expert knowledge for investigating cells and tiss

https://www.stemcellcenter.lu.se/article/lund-scc-and-multipark-join-forces-ensure-researchers-have-high-quality-electrophysiology-facilities - 2025-08-21

The MSCA Logo (left) and a photo of Camila Vazquez Echegaray (right). The Marie Skłodowska-Curie Actions (MSCA) fund excellent research and innovation. This March, the MSCA awarded €242m to the 2021 Postdoctoral Fellowships applicants – among them, a researcher from Lund University, Camila Vazquez Echegaray, aiming to uncover regulators of plasticity in cell fate decision. The MSCA are the EU’s fl

https://www.stemcellcenter.lu.se/article/msca-postdoctoral-fellowship-awarded-camila-vazquez-echegaray - 2025-08-21

Cancerfonden distributed SEK 37 million to 8 researchers at Lund University in 2022. Included in this group is, Dr. Sowndarya Muthukumar (left). Cancerfonden continues to fund the foremost cancer research in Sweden – investing in cancer research that makes a difference. Last month, Cancerfonden distributed SEK 37 million to eight researchers at Lund University whose work will contribute to defeati

https://www.stemcellcenter.lu.se/article/cancerfonden-awards-sowndarya-muthukumar-postdoctoral-fellowship - 2025-08-21

Cancer is a genetic disease, caused by a change in the genes which make up our DNA. Normally one change or mutation is not enough to trigger the development of cancer, instead cancer is typically comprised of a combination of genetic mutations. Researchers at Lund University have now revealed a novel somatic gene mutation is involved in the formation and progression of acute myeloid leukemia. The

https://www.stemcellcenter.lu.se/article/new-findings-reveal-what-may-be-triggering-disease-progression-acute-myeloid-leukemia - 2025-08-21

Fluorescent microscope image of control MBP-positive oligodendrocytes (in green) co-stained with alpha-synuclein (in red). It is possible to observe neurites positive for alpha-synuclein. Photo Credit: Carla Azevedo. Researchers from Lund University, led by Dr. Laurent Roybon, are working to further define underlying mechanisms involved in neurodegenerative diseases, such as Parkinson’s Disease an

https://www.stemcellcenter.lu.se/article/new-findings-may-lead-way-future-therapeutic-approaches-parkinsons-disease-and-similar-diseases - 2025-08-21

A laboratory expert in action in the Cell and Gene Therapy Core Facility. Lund Stem Cell Center provides researchers with access to core facilities equipped with the latest technologies, specialist expertise and instruction on the use of the different equipment. Over time these facilities have evolved to form the well-developed technological infrastructure which exists today. Earlier this year, th

https://www.stemcellcenter.lu.se/article/new-cell-and-gene-therapy-core-facility-opening-its-doors-scientific-business - 2025-08-21

Photo of the BMC building (left) and a portrait of Sandeep Gopal (right). We are happy to announce that Sandeep Gopal, a researcher within the Department of Experimental Medical Sciences at Lund University, has now joined Lund Stem Cell Center. In his new role as Principal Investigator and leader of the research group on Extracellular Signaling and Cell Fate, he aims to better understand how extra

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-welcomes-new-member-sandeep-gopal - 2025-08-21

The members of the Stem Cell and Leukaemia Research Group. Researchers at Lund University have recently sought to shed more light on how normal hematopoietic stem cells (HSCs) produce a vast variety of blood cells. Their latest findings, now out in Cell Reports this week, confirm the existence of a transition state as HSCs develop into functional blood cells and provide insights into how certain p

https://www.stemcellcenter.lu.se/article/shedding-new-light-intermediate-cell-states-stem-cells-decide-their-fate - 2025-08-21

Paul Bourgine, researcher and Wallenberg Fellow in Molecular Medicine, has been awarded an ERC Proof of Concept, consisting of EUR 150,000. Photo: Kennet Ruona. By using cells isolated from cancer patients and mixing them with a new technology called “OssiGel”, it is possible to engineer human mini-bones. These miniaturized organs consist of mature bone and marrow tissue and can be used as model t

https://www.stemcellcenter.lu.se/article/miniature-bones-research-model-cancer - 2025-08-21