Human iPS cells Photo: Johan Jakobsson Diabetes, cardiovascular disease, Parkinson's and Alzheimer's disease make up the world’s most common diseases. A new biobank at Lund University in Sweden - the largest of its kind - with stem cells from both those affected and healthy individuals, will contribute to an increased understanding of how these diseases arise. “The goal is for researchers to be ab

https://www.stemcellcenter.lu.se/article/worlds-largest-stem-cell-biobank-launched-0 - 2025-08-21

UniStem day 2020 High school students from all over the Skåne region will be visiting Lund University to spend a whole day discussing the current state of stem cell research, discovering what it is like to work in a research setting, and exploring the exciting future possibilities that stem cells have to offer. Building on the success of the previous five years, Lund Stem Cell Center is hosting Un

https://www.stemcellcenter.lu.se/article/continued-interest-stem-cells-among-high-school-students - 2025-08-21

PI Agnete Kirkeby. Photo: Kennet Ruona Wallenberg Molecular Medicine Fellow Agnete Kirkeby has re-established her research group at Lund Stem Cell Center. With labs situated at both Lund and at the Department of Neuroscience at Copenhagen University, Agnete’s aim is to develop stem cell-based neural cell therapies to replace lost neurons as a treatment for brain diseases. As a main project, the Ki

https://www.stemcellcenter.lu.se/article/pi-agnete-kirkeby-returns-lund-stem-cell-center - 2025-08-21

Lund Stem Cell Center employees and students are hereby invited to enter the Image Competition 2020! We want inspirational images that capture the spirit of Lund Stem Cell Center. Any research related images will be accepted. Not just pictures of cells or sections, it could be your work environment, equipment, imaging, laboratory researchers, it’s up to you! We want to showcase the amazing researc

https://www.stemcellcenter.lu.se/article/lund-stem-cell-center-image-competition-2020 - 2025-08-21

VIdeo: Experiences from UniStem Day 2020 UniStem Day 2020 was another great success, with high school students visiting Lund University to enjoy a variety of activities introducing them to the fascinating world of stem cell research. The 6th UniStem day hosted by Lund University kicked off at the LUX Aula lecture theatre, Lund University, where over 200 high school students from over the Skåne reg

https://www.stemcellcenter.lu.se/article/bringing-stem-cell-research-next-generation-scientists - 2025-08-21

Transplanted nerve cells (upper right) made from human skin cells send their nerve fibers to the cerebral cortex on the opposite side of the brain. Image source: Zaal Kokaia. Researchers from Lund University have now succeeded in restoring mobility and sensation in rats that have suffered Stroke, by transplanting neurons developed from reprogrammed human skin cells into animal brains. “Six months

https://www.stemcellcenter.lu.se/article/scientists-repair-stroke-damaged-rat-brain-1 - 2025-08-21

Daniela Grassi defends her thesis on Thursday 23rd April. Photo: Kennet Ruona With a research focus on the development and application of in vitro models to study human brain evolution and disease, PhD student Daniela Grassi will be defending her thesis on Thursday 23rd of April 2020. Here, Daniela tells us about her research in the Molecular Neurogenetics group, led by Johan Jakobsson, and her ti

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-daniela-grassi - 2025-08-21

Carla Azevedo defends her thesis on Thursday 30th April Carla Azevedo is set to defend her PhD thesis titled “Oligodendroglial (dys)function in alpha-synucleinopathies” on Thursday 30th of April. Here, Carla answers a few questions about her PhD journey at Lund Stem Cell Center, researching in the iPSC Laboratory for CNS disease modeling. How did you end up doing a PhD at Lund Stem Cell Center?I’m

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-carla-azevedo - 2025-08-21

Accumulating levels of protein aggregates characteristic of Huntington disease (left) can be reduced by boosting autophagy (right). Image source: Karolina Pircs. Huntington disease is fatal inherited brain disorder, usually emerging during mid-life. Although there is currently no known cure, the Molecular Neurogenetics group at Lund Stem Cell Center aims to understand the defective cellular proces

https://www.stemcellcenter.lu.se/article/autophagy-and-treatment-huntington-disease-timing-key - 2025-08-21

Image of a human embryo surrounded by placenta, around 7 weeks of age. Image credit Hill, M.A. (2020, May 18) Embryology  Stem cell researchers at Lund University in Sweden have developed a new research model of the early embryonic brain. The aim of the model is to study the very earliest stages of brain to understand how different regions in the brain are formed during embryonic development. With

https://www.stemcellcenter.lu.se/article/new-method-provides-unique-insight-development-human-brain - 2025-08-21

Neuroblasts (green) in the aged brain traveling from the subventricular zone (SVZ) to the olfactory bulb (OB) via the rostral migratory stream (RMS). Proliferating cells are shown in red. Image from Jonas Fritze. Neurogenesis, the process by which new neurons are formed, dramatically declines in the aging brain. A research group from Lund Stem Cell Center have published a study that sheds light on

https://www.stemcellcenter.lu.se/article/researchers-identify-novel-regulator-neurogenesis-aged-brain - 2025-08-21

Franziska Olm will defend her PhD thesis on Friday 12th June 2020 PhD student Franziska Olm has been developing a microfluidic-based acoustophoresis method to process stem cell preparations label-free, a technique with great research and clinical potential. In this interview, Franziska tells us about her PhD project, her time at Lund Stem Cell Center and her plans following her thesis defence on F

https://www.stemcellcenter.lu.se/article/thesis-defence-interview-franziska-olm - 2025-08-21

Postdoctoral researcher Agatheeswaran Subramaniam and PhD Student Kristijonas Žemaitis from the Stem Cell Regulators research group. Photo: Alexander Doyle Researchers from Lund Stem Cell Center have identified a novel target for the expansion of human blood stem cells ex vivo and shed light on the mechanism of action of a stem cell promoting molecule, currently in phase II clinical trials. Hemato

https://www.stemcellcenter.lu.se/article/new-insights-ex-vivo-expansion-transplantable-human-blood-stem-cells - 2025-08-21

Electron microscopy image of hematopoietic stem/progenitor cell on top of nanostraws. Image credit: M. Hjort and L. Schmiderer Researchers from Lund University have developed a promising new method for delivering biomolecules into human blood stem cells using nanotechnology. With little to no detrimental effects on target cells, this novel approach has great potential for research and clinical app

https://www.stemcellcenter.lu.se/article/nanostraws-used-deliver-biomolecules-stem-cells - 2025-08-21

Sofie Mohlin and Maciej Ciesla with their images, currenlty on display at BMC Lund, level D15. Those who find themselves at Lund BMC can now discover exciting new artwork highlighting the visual side of research. Created by researchers from the Faculty of Medicine, these images were part of ‘The invisible body – art in science’ exhibition held in Stockholm. Here, Christine Karlsson - director of t

https://www.stemcellcenter.lu.se/article/striking-research-images-decorate-lund-biomedical-center - 2025-08-21

Johan Jakobsson and Johan Flygare. Photo credit: Kennet Ruona Prof. Johan Jakobsson has been appointed as coordinator and Assoc. Prof. Johan Flygare as deputy coordinator of StemTherapy and Lund Stem Cell Center.Together they will continue to manage StemTherapy and Lund Stem Cell Center towards scientific and educational excellence, whilst strengthening the direction of translational research. We

https://www.stemcellcenter.lu.se/article/new-leadership-lund-stem-cell-center - 2025-08-21

Dr. Yuriy Pomeshchik (left) and Dr. Laurent Roybon, lead and senior authors of the study. Photo: Agata Garpenlind Neuroscientists and stem cell researchers at Lund University in Sweden have developed a research model that allows studying human hippocampal neurons, the brain cells primarily affected by Alzheimer’s disease pathology. The study has been published in Stem Cell Reports. In Alzheimer’s

https://www.stemcellcenter.lu.se/article/new-research-paves-way-developing-therapies-could-slow-down-alzheimers - 2025-08-21

Minaturized human bone organs, called “human ossicles”. Image credit: Laboratory for Cell, Tissue and Organ Engineering. Congratulations to Lund Stem Cell Center PI and Wallenberg Fellow Paul Bourgine, who has been awarded European Research Council funding. His research group, the Laboratory for Cell, Tissue and Organ Engineering, are using engineered miniaturized human bone organs to better under

https://www.stemcellcenter.lu.se/article/paul-bourgine-awarded-prestigious-european-research-council-grant - 2025-08-21

Immunofluorescence image of human neurons derived from stem cells. Image credit: Agnete Kirkeby Prof. Johan Jakobsson and Assoc. Prof. Agnete Kirkeby from Lund Stem Cell Center and University of Copenhagen, along with co-applicants Prof. Roger Barker from Cambridge, UK and Assoc. Prof. Molly Hammell from Cold Spring Harbour Laboratory, US, have been awarded a prestigious grant from the Aligning Sc

https://www.stemcellcenter.lu.se/article/researchers-investigate-role-transposable-elements-neuroinflammation-and-parkinsons-disease - 2025-08-21

Histopathology of rescued bone. Femur of an osteopetrotic mouse (left) and rescued bone phenotype in femur following lentiviral mediated gene therapy. Image credit: Johan Richter & Ilana Moscatelli Johan Richter's research has resulted in the successful development of gene therapy for the hereditary disease malignant infantile osteopetrosis. For the past few years, the research group has establish

https://www.stemcellcenter.lu.se/article/successful-biotech-collaboration-brings-gene-therapy-project-clinic - 2025-08-21