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Storage period optimization of a viscous nasal spray suspension

The number of people suffering from the unpleasant symptoms of allergic rhinitis is increasing due to environmental and other factors. This not only makes life difficult for the individual but also places a heavy burden on society, which is why treatment is needed. Rhinocort® is a nasal spray suspension manufactured by McNeil AB to reduce the severity of symptoms, and like all medicines, must und

Landscape effects on pollen foraging and competition among bumblebees

Hur landskapskvalitet påverkar humlors födosök efter pollen Under de senaste århundradena har det skett en nedgång i både antal arter och individer av humlor. Den förmodligen viktigaste anledningen till detta är den förändrade landskapsstrukturen som uppstått till följd av intensifieringen av jordbruket. Detta har lett till större och mer enformiga fält, samtidigt som naturliga (och halvnaturligaBumblebee abundance and diversity have been declining in the last few decades. Habitat change, mainly due to intensified agricultural practices, has been pointed out as the main driver in this process. Being central place foragers bumblebees are highly dependent on the landscape surrounding the nest and the resources available there. According to the optimal foraging theory bumblebee individuals i

”The Sea City” in Trelleborg: A climate-adapted design proposal to combat flooding from cloudbursts and rising sea levels

Scientific studies indicate that the effects of the ongoing climate crisis negatively affect and sometimes also threaten the built environment, humanity and nature in many ways. Cloudbursts and rising sea levels are two examples of such effects, which result in complex dilemmas and interesting challenges that planners and urban designers face within their field of work. These two effects are notic

Assessing Offshore Wind System Integration: Comparative Analysis of Floating Photovoltaics, Oscillating Surge Wave Converters, and Battery Energy Storage Systems

Detta examensarbete ämnar att undersöka integration av tre olika teknologier till en havsbaserad vindkraftspark, om det är ekonomiskt gynnsamt samt hur kraftfluktuationerna till elnätet påverkas. Genom att kombinera olika förnybara kraftsystem kan man minska variabiliteten och kostnaderna kopplade till installation och drift av systemen. Även fast investeringar i annan förnybar energi utöver vindkThe high penetration of wind power is increasing the intermittency and power variability into the existing power grid. This is forcing industries to look for optimal configurations in order to improve their systems performance and minimize these effects from the power production method. Studies show that there are different ways of reducing the power variability and therefore stabilize the energy

Principen jura novit curia och klander: En analys om tillämpningen av principen jura novit curia i skiljeförfarande - med särskilt fokus på principen som klandergrund

Principen jura novit curia är en central och vedertagen princip i svensk processrätt och tillämpas i domstolsprocessen. Principens relevans och tillämpning i skiljeförfarande är dock inte lika självklar mot bakgrund av skiljeförfarandets syften och bakomliggande principer. Frågan om en skiljenämnd kan, bör eller ska tillämpa principen jura novit curia på motsvarande sätt som i domstolsprocessen akThe principle of jura novit curia is a central and well-established tenet in Swedish procedural law, applied within court proceedings. However, its relevance and application in arbitration is not as clear, given the purposes and underlying principles of arbitration. The question of whether an arbitral tribunal can, should, or must apply the principle of jura novit curia in the same manner as in co

Airing with side-hung and pivot-hung windows - Simulations and heat loss

Efforts to reduce energy consumption in buildings have increased with the pending impact of climate change. Heat losses through airing behaviours remain a largely unknown factor due to the variety of reasons for opening a window, making generalization difficult. Currently, an estimation of 4 kWh/m2 heated area for airing heat loss is assumed in Sweden. Additionally, the resulting airflow from open

Expanded Codon Technology for Producing Phosphorylated Enamel Matrix Protein

Amelogenin, a critical protein in enamel formation, self-assembles into supramolecular structure that guide hydroxyapatite (HAP) crystal growth that is essential for the development of strong and healthy enamel. Phosphorylation of amelogenin at Ser-16 plays a pivotal role in modulating its self-assembly and functional properties, impacting the overall enamel biomineralization process. This post-tr

Shade and Light Modeling for Agrivoltaic Systems- With Focus on Single-Axis Agrivoltaic Systems

Global population growth presents challenges to sustainable food and energy produc- tion. Transitioning to renewable energy sources, like solar power, requires significant land allocations, conflicting with the need for arable farmland. Agrivoltaics (AV) offers a potential solution by integrating crops and solar panels on the same land. Ensuring consistent and adequate agricultural output alongsid

Methane Emission Quantification Using UAV-based Measurements - Comparing Existing Landfill Methane Monitoring Methods

According to the Intergovernmental Panel on Climate Change (IPCC), atmospheric methane (CH4) concentrations are considered a crucial factor in global warming, particularly in the near term, due to its high warming potential (~ 80 times more potent than carbon dioxide, or CO2) and shorter atmospheric lifetime compared to CO2. CH4 emissions have more than doubled since the industrial revolution and

Laboratory Testing of Stormwater from Värpinge Wetland Using SiC Membrane

Stormwater runoffs have increasingly become a significant issue in urban infrastructure design and environmental management due to problems related to flooding, freshwater stress, and pollutant loading to receiving water bodies. This project investigated the lab-scale performance of silicon carbide (SiC) MF membranes in treating stormwater runoffs from the Värpinge wetland in the western part of t

Sorghum for Sweden? Perspectives on Climate-Resilient Crop Adoption from the Field

In Sweden, climate projections indicate longer growing seasons with more frequent extreme weather events, such as droughts and heavy rainfall, posing significant challenges to existing crop systems. Simultaneously, the sector is under growing pressure to reduce its environmental footprint, especially in response to agricultural nutrients runoff contributing to the eutrophication of the Baltic Sea.

Celestial Orientation in Dim Light

The polarization pattern of skylight offers many animals a reference for visual compass orientation. In those cases when this optical compass is identified, the receptors involved are often confined to a small part of an eye built predominantly for other visual tasks. This thesis reports the discovery of a unique compass organ in the spider Drassodes cupreus, where a pair of specialised secondary

The impact of human constructions on the areal extent of Italian Tuscany forests

Abstract Trying to preserve the forest is an important issue considering its tremendous impact on the ecosystem and subsequently on humans and their lives. On the other hand, humans have changed the area of the forest in different ways. Therefore, investigating the human impact and helping to prevent the destruction of the forest plays a vital role in preserving biodiversity and maintaining ecosys

Action-detected 2D spectroscopy : Technical development and practical applications

This doctoral thesis presents a comprehensive investigation into action-detected two-dimensional electronic spectroscopy (A-2DES), from the technical development of a state-of-the-art apparatus to its application in elucidating ultrafast dynamics in advanced materials and biological systems. The work is founded on the design and implementation of an A-2DES setup centered on a single acousto-optic

Chemoradiation Therapy Versus Radiation Therapy Alone in T1-2 Oropharyngeal Cancer With Low-Volume Neck Disease: A Population-Based Cohort Study Using the Swedish Head and Neck Cancer Register

PurposeThe benefit of adding concurrent systemic therapy to definitive radiation therapy (RT) for patients with T1-2 oropharyngeal squamous cell carcinoma (OPSCC) and limited neck node involvement is uncertain. This study investigates whether chemotherapy (CRT) in patients with early-stage (T1-2) low-volume nodal disease (Union for International Cancer Control Seventh Edition N1-2b) improves overa

Assessing the effects of mining projects on child health in sub-Saharan Africa : a multi-country analysis

Background: The African continent hosts many industrial mining projects, and many more are planned due to recent prospecting discoveries and increasing demand for various minerals to promote a low-carbon future. The extraction of natural resources in sub-Saharan Africa (SSA) represents an opportunity for economic development but also poses a threat to population health through rapid urbanisation a

Epithelioid and Spindle Cell Hemangioma : Clinicopathologic Analysis of 18 Primary Bone and Soft Tissue Tumors Highlighting a Predilection for the Hands and Feet, Frequent Multicentricity, and Benign Behavior

Epithelioid and spindle cell hemangioma was initially described in 1999 in a series of primary bone tumors and was subsequently suggested by some to represent a variant of epithelioid hemangioma. Here, we studied 18 epithelioid and spindle cell hemangiomas. Nine patients (50%) were male. Age at presentation ranged from 12 to 78 years (median: 38.5 y). Nine patients (50%) had tumor(s) limited to bo

Liver saturated fat content associates with hepatic DNA methylation in obese individuals

Background: Accumulation of saturated fatty acids (SFAs) in the liver is known to induce hepatic steatosis and inflammation causing non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Although SFAs have been shown to affect the epigenome in whole blood, pancreatic islets, and adipose tissue in humans, and genome-wide DNA methylation studies have linked epigenetic ch