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Genome-wide search for breast cancer linkage in large Icelandic non-BRCA1/2 families

Introduction: A significant proportion of high-risk breast cancer families are not explained by mutations in known genes. Recent genome-wide searches (GWS) have not revealed any single major locus reminiscent of BRCA1 and BRCA2, indicating that still unidentified genes may explain relatively few families each or interact in a way obscure to linkage analyses. This has drawn attention to possible be

Hydrological Modelling, Topographical Influence and Yield Mapping in Precision Agriculture

The use of topographical data in hydrological and agricultural applications has increased with GPS data availability and the concept of precision agriculture. This thesis investigates the relationships between topography and in one case simulated soil moisture and in the other case yield. The yield was recorded with a new optical sensor, which uses a digital camera to detect objects and records th

Early Paleogene biosiliceous sedimentation in the Atlantic Ocean : Testing the inorganic origin hypothesis for Paleocene and Eocene chert and porcellanite

The widespread occurrence of lower Eocene chert and porcellanite has been viewed as a major paleoceanographic issue since the advent of ocean drilling, and both biotic and abiotic forcings have been proposed to explain it. We present a reconstruction of indurated siliceous sediment (ISS) and preserved biosiliceous sediment (PBS) occurrences in the Atlantic Ocean through the Paleocene and Eocene (~

Differences in incubation behaviour and niche separation of two competing flycatcher species

Abstract: Food availability sets the stage for incubation behaviour of a female bird and thereby indirectly determines the nest temperature, which in turn affects development and metabolism of avian embryos. Changes in development and metabolism in turn are known to influence offspring’s ability to adjust to environmental changes later in life. However, few studies have investigated the role of in

Selected research studies from Scandinavia : dedicated to professor Göran Fagerlund on his 60th anniversary November 11, 1997

The book contains selected articles from research in different areas produced by scientists in Scandinavia. However, many of the articles are based upon professor Göran Fagerlund's original ideas. Titles:

1.Cementitious injection grouts - penetration ability (Alemo, J. & Hansson, P.).
2.A disadvantage of high performance concrete and a simple way to avoid it (Alexanderson, J).

A method for analysing the traffic process in a safety perspective

The aim of this study is to extend the traffic safety assessment concept to also include normal road user behaviour, thus not only exceptional behaviours such as accidents and serious conflicts. The goal is to provide a framework for a more thorough description and analysis of safety related road user behaviour in order to better understand the traffic safety processes. The traffic safety process

Some Notes on Present European and Scandinavian Co-production Practices Through the Prism of ‘The Girl with the Dragon Tattoo’ (2009)

In a critique of the sometimes confusing ways in which the term transnational has been repeatedly used, Mette Hjort, in 2010 attempted to outline what she called a “typology of transnationalisms” in connection with contemporary audio-visual production (2009: 12–33). Hjort’s palpable purpose here is to more specifically illuminate and contextualize the increasingly more used concept of transnationa

Single versus serial measurements of neuron-specific enolase and prediction of poor neurological outcome in persistently unconscious patients after out-of-hospital cardiac arrest - A TTM-trial substudy

Background: Prediction of neurological outcome is a crucial part of post cardiac arrest care and prediction in patients remaining unconscious and/or sedated after rewarming from targeted temperature management (TTM) remains difficult. Current guidelines suggest the use of serial measurements of the biomarker neuron-specific enolase (NSE) in combination with other predictors of outcome in patients

Seeking explanations for recent changes in abundance of wintering Eurasian Wigeon (Anas penelope) in northwest Europe

We analysed annual changes in abundance of Eurasian Wigeon (Anas penelope) derived from mid-winter International Waterbird Census data throughout its northwest European flyway since 1988 using log-linear Poisson regression modelling. Increases in abundance in the north and east of the wintering range (Norway, Sweden, Denmark, Germany, Switzerland), stable numbers in the central range (Belgium, Net

Whole-remnant and maximum-voxel SPECT/CT dosimetry in 131I-NaI treatments of differentiated thyroid cancer

Purpose: To investigate the possible differences between SPECT/CT based whole-remnant and maximum-voxel dosimetry in patients receiving radio-iodine ablation treatment of differentiated thyroid cancer (DTC). Methods: Eighteen DTC patients were administered 1.11 GBq of 131I-NaI after near-total thyroidectomy and rhTSH stimulation. Two patients had two remnants, so in total dosimetry was performed f

Bipolar volcanic synchronization of abrupt climate change in Greenland and Antarctic ice cores during the last glacial period

The last glacial period is characterized by a number of millennial climate events that have been identified in both Greenland and Antarctic ice cores and that are abrupt in Greenland climate records. The mechanisms governing this climate variability remain a puzzle that requires a precise synchronization of ice cores from the two hemispheres to be resolved. Previously, Greenland and Antarctic ice

The influence of small-scale variations in isoprene concentrations on atmospheric chemistry over a tropical rainforest

Biogenic volatile organic compounds (BVOCs) such as isoprene constitute a large proportion of the global atmospheric oxidant sink. Their reactions in the atmosphere contribute to processes such as ozone production and secondary organic aerosol formation. However, over the tropical rainforest, where 50 % of the global emissions of BVOCs are believed to occur, atmospheric chemistry models have been

A new retrieval algorithm for soil moisture index from thermal infrared sensor on-board geostationary satellites over Europe and Africa and its validation

Monitoring soil moisture at the Earth'surface is of great importance for drought early warnings. Spaceborne remote sensing is a keystone in monitoring at continental scale, as satellites can make observations of locations which are scarcely monitored by ground-based techniques. In recent years, several soil moisture products for continental scale monitoring became available from the main space age

Exploring the Effects of Deep Brain Stimulation and Vision on Tremor in Parkinson's Disease : Benefits from Objective Methods

BACKGROUND: Tremor is a cardinal symptom of Parkinson's disease (PD) that may cause severe disability. As such, objective methods to determine the exact characteristics of the tremor may improve the evaluation of therapy. This methodology study aims to validate the utility of two objective technical methods of recording Parkinsonian tremor and evaluate their ability to determine the effects of Dee

Two-neutron interferometry as a probe of the nuclear halo

The technique of intensity interferometry is proposed as a probe of the spatial configuration of two-Neutron haloes. After exploring the sensitivity of interferometry to the n-N configuration, it is demonstrated that the application of the standard method for constructing the correlation function is not valid for halo neutrons. A new iterative method is presented and applied to measurements of the

Bottom-water oxygenation and environmental change in Santa Monica Basin, Southern California during the last 23kyr

The Southern California Borderland is a region that experiences strong natural variations in bottom water oxygen and pH. We use marine sediments from Santa Monica Basin to reconstruct environmental conditions in the basin's bottom water from the Last Glacial Maximum (LGM) to present. We then compare the records to the adjacent Santa Barbara Basin and Santa Lucia Slope. High-resolution records of b