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BACKGROUND AND AIMS: Autoantibodies against the zinc transporter 8 (ZnT8A) are common in type 1 diabetes (T1D). ZnT8A analyses are complicated by the fact that there are three variants of the autoantigen at amino acid position 325 representing ZnT8-R (Arginine), ZnT8-W (Tryptophan) and ZnT8-Q (Glutamin). The aims of the study were: 1) to develop an autoantigen triple mix Radio-Binding Assay (RBA)

A study of the ambitions of the managers at AB Robertsfors Bruk and their impact on courses of action in the development of wage policy and social arrangements in the community of Robertsfors during the period 1925-35.This study deals with employer actions during a period of both internal and external change to the organization. The main focus is in the areas of wage policy and social arrangements

Future anthropogenic climate change is likely to increase the air temperature (T a ) across Europe and increase the frequency, duration and magnitude of severe heat stress events. Heat stress events are generally associated with clear-sky conditions and high T a , which give rise to high radiant heat load, i.e. mean radiant temperature (T mrt ). In urban environments, T mrt is strongly influenced

Popular Abstract in Swedish Den moderna tekniken att operera förslitna höftleder infördes av John Charnley i England på 1960-talet. Lårbenshuvudet ersattes med en metallkula på ett skaft och ledhålan på bäckenbenet med en skålformad plastkomponent. Bägge komponenterna sattes fast med en härdande plast, s.k. bencement. I början uppstod komplikationer med infektioner eller brott i själva protesen. DThis thesis focuses on the healing and remodeling of the morselized and impacted bone allograft, commonly used in revision of loosened hip prostheses with osteolysis. The influence on remodeling by the impaction procedure per se was analyzed, as well as the effects of endogenous bone graft proteins, and an exogenously applied growth factor (OP-1). A bone chamber model in rats was used, with the in

Precipitation is often the sole source of water replenishment in arid and semi-arid areas and, thus, plays a pertinent role in sustaining desert ecosystems. Revegetation over 40 years using mainly Artemisia ordosica and Caragana korshinskii at Shapotou Desert Experimental Research Station near Lanzhou, China, has established a dwarf-shrub and microbiotic soil crust cover on the stabilized sand dun

Declining biological production as a part of an ongoing land degradation process is considered a severe environmental problem in the dry northern and northwestern regions of China. The aim of this study is to develop and adapt a satellite data-driven gross primary production model called Lund University light use efficiency model (LULUE) to temperate conditions in order to map gross primary produc

Objectives. The EGFR is expressed in malignant ovarian tumor tissue, and tissue content of EGFR has been directly associated with poor prognosis in patients with ovarian cancer. The uPA system plays a role in pericellular proteolysis, cell migration, invasion, and is over-expressed in ovarian cancer. This study explored the effects of EGF on uPAR expression in the ovarian cancer cell line OVCAR-3.

Background and objectives In accordance with clinical findings, myringoscterosis develops after otitis media (OM) and paracentesis in an experimental setting. The pathogenesis of this phenomenon of calcification is poorly understood. As the calcification process and the sclerotic plaques of the drum mimics features of bone tissue, this study explores tympanic membrane calcium deposition in associa

Arsenic enrichment of groundwater in the Red River (Song Hong) delta in Vietnam was discovered in 1998. Several studies performed in this area found concentrations of As exceeding the WHO-guideline of 10 lg/L. This study focuses on an area south of Hanoi city, Nam Du, where a new well field came into operation in 2004. The new well field is situated on the bank along the Red River in order to faci

It is a textbook knowledge that charges of the same polarity repel each other. For two monovalent ions in the gas phase at a close contact this repulsive interaction amounts to hundreds of kilojoules per mole. In aqueous solutions, however, this Coulomb repulsion is strongly attenuated by a factor equal to the dielectric constant of the medium. The residual repulsion, which now amounts only to uni

Arguably among the most globally impactful climate changes in Earth's past million years are the glacial terminations that punctuated the Pleistocene epoch. With the acquisition and analysis of marine and continental records, including ice cores, it is now clear that the Earth's climate was responding profoundly to changes in greenhouse gases that accompanied those glacial terminations. But the u

This thesis consists of four self-contained papers in applied microeconomics. The first paper asks how a neighbors purchase of a specific good affects a households likelihood of purchase. I use an image classification algorithm to process a large set of aerial photos in order to infer household ownership of a visible durable good, specifically a trampoline. To estimate the neighborhood effect, I u

BACKGROUND: In mitral valve dysfunction, noninvasive measurement of transmitral blood flow is an important clinical examination. Flow imaging of the mitral valve, however, is challenging, since it moves in and out of the image plane during the cardiac cycle.PURPOSE: To more accurately measure mitral flow, a slice-following MRI phase contrast sequence is proposed. This study aimed to implement such

Billions of animals are adapted to a travelling life, making regular return migrations between more or less distant living stations on Earth by swimming, flying, running or walking (Figure 1). Extremely long migrations are completed annually by whales between calving areas in warmer waters and feeding areas at higher latitudes in either hemisphere. The longest oceanic migrations among sea turtles

Globins are usually associated with oxygen carriage in vertebrates. However, plants also contain similar heme-containing proteins, called phytoglobins (Pgbs). Unlike conventional hemoglobin, these proteins are often linked to nitric oxide metabolism, energy metabolism and redox maintenance under hypoxic and related abiotic and biotic stress conditions. Class I and II non-symbiotic Pgbs (nsPgbs) ha

Climatic extreme events are expected to occur more frequently in the future, increasing the likelihood of unprecedented climate extremes (UCEs) or record-breaking events. UCEs, such as extreme heatwaves and droughts, substantially affect ecosystem stability and carbon cycling by increasing plant mortality and delaying ecosystem recovery. Quantitative knowledge of such effects is limited due to the

När vi människor försöker röra på oss skickas elektriska impulser genom nervsystemet från hjärnan ner till de muskler som är inblandade i den tilltänkta rörelsen. Att kunna mäta sådana nervimpulser hade varit av värde för en rad tillämpningar—information hade då kunnat överföras direkt från nervsystemet utan att gå via långsamma, mekaniska gränssnitt så som tangentbord och pekskärmar. OlyckligtvisElectrical activity produced by muscles during voluntary movement is a reflection of the firing patterns of relevant motor neurons and, by extension, the latent motor intent driving the movement. Once transduced via electromyography (EMG) and converted into digital form, this activity can be processed to provide an estimate of the original motor intent and is as such a feasible basis for non-invas

Adsorption isotherms taken at temperatures ranging from 20 to 77 K show a large pore volume and surface area of 980 m2 g-1 for the physical adsorption of molecular hydrogen on MCM-41. The adsorbed hydrogen behaves more like a solid than a liquid and isosteric heats of adsorption reveal a heterogenous surface. The evaporation behaviour of the adsorbed hydrogen indicates that the hexagonally packed

This doctoral thesis is concerned with agency in the work of a performer, curator, and composer, and how these agencies are socio-culturally constructed. Grounded in creative practice as primary research methodology, the project builds on feedback loops between creation, analysis, and interpretation. The aim is to better understand the conventional norms that define the roles of composer and perfo