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The paper explores the usage of minimax adaptive controllers to guarantee finite L2 -gain simultaneous stabilization of linear time-invariant (LTI) plants. It is shown that a minimax adaptive controller simultaneously stabilizes any two multiple-input multiple-output (MIMO) P-stabilizable LTI plants when no LTI controller can achieve that, and the worst attained L2 -gain bound for the transient dy
Target-controlled infusion (TCI) constitutes a clinically available alternative to manually administering the infusion rate of the anesthetic drug propofol. In TCI, a drug infusion profile is optimized to track a reference trajectory of blood plasma or effect site (brain cortex) drug concentration, or a corresponding clinical effect. TCI is a pure feed-forward openloop strategy, fully reliant on a
We conduct a field experiment studying how financial incentives for achieving specific course grades affect university students, whether effects vary by ability, and whether allowing students to choose their goals improves outcomes. We find that incentives negatively affect performance, particularly among low-ability students assigned high goals. Survey data suggest this negative impact arises fro
Human physiology is the study of how organisms, organ systems, and individual organs function under normal circumstances. As a consequence of its paramount importance to medicine, physiology has been studied since ancient times, but the models studied in this book follow the tradition of modern physiology pioneered by Claude Bernard in the mid 1800s.The focus of the book lies on how dynamical mech
When addressing lying and deception in language production, it is imperative to acknowledge that behavioral indicators may play a role. This include evaluation of multiple distinct verbal and nonverbal behavioral indicators, such as gaze cues, pulse rate, hand movements, and manifestations of nervousness. Here, the role of cognitive load during speaking and writing, and how cognitive load due to t
Pharmacometric modeling plays an important role in drug development and personalized medicine. Pharmacometric covariate models can be used to describe the relationships between patient characteristics (such as age and weight) and pharmacokinetic (PK) parameters. Traditionally, the functional structure of these relationships are obtained manually. This is a time-consuming task, and consequently lim
The temporal dynamics of the perception of within-word coarticulatory cues remain a subject of ongoing debate in speech perception research. This behavioral gating study sheds light on the unfolding predictive use of anticipatory coarticulation in onset fricatives. Word onset fricatives (/f/ and /s/) were split into four gates (15, 35, 75 and 135 milliseconds). Listeners made a forced choice about
We propose that a recently discovered event-related potential (ERP) component—the pre-activation negativity (PrAN)—indexes the predictive strength of phonological cues, including segments, word tones, and sentence-level tones. Specifically, we argue that PrAN is a reflection of the brain’s anticipation of upcoming speech (segments, morphemes, words, and syntactic structures). Findings from a long
Digitally animated characters are promising tools in research studying how we integrate information from speech and visual sources such as gestures because they allow specific gesture features to be manipulated in isolation. We present an approach combining motion capture and 3D-animated characters that allows us to manipulate natural individual gesture strokes for experimental purposes, for examp
In embedded computing domains, including the automotive industry, complex functionalities are split across multiple tasks that form task chains. These tasks are functionally dependent and communicate partial computations through shared memory slots based on the Logical Execution Time (LET) paradigm. This paper introduces a model that captures the behavior of a producer-consumer pair of tasks in a
We are currently witnessing the second wave of cloud services that go beyond web storefronts and IT systems, aiming for digitalization of industrial systems. Automation and time-sensitive systems are now taking their first steps toward the cloud. The AORTA project aims to facilitate this transition by providing key technology components needed for real-time services running in the cloud. The ambit
Objective: Long-term automatic detection of focal seizures remains one of the major challenges in epilepsy due to the unacceptably high number of false alarms from state-of-the-art methods. Our aim was to investigate to what extent a new patient-specific approach based on similarly occurring morphological electroencephalographic (EEG) signal patterns could be used to distinguish seizures from nons
Among the hundreds of known hot Jupiters (HJs), only five have been found to have companions on short-period orbits. Within this rare class of multiple planetary systems, the architecture of WASP-47 is unique, hosting an HJ (planet-b) with both an inner and an outer sub-Neptunian mass companion (-e and -d, respectively) as well as an additional non-transiting, long-period giant (-c). The small per
Feather mites play an important role in bird communities, covering a wide spectrum of associations with their hosts, ranging from parasitic to mutualistic relations. As a result of long co-evolution with their warm-blooded hosts, this diverse group of arthropods can be found in a wide range of environments where their hosts occur, including the high Arctic. The feather mite fauna of Greenland is p
Speaking in poor acoustic conditions constitutes a risk factor for voice disorders. This study investigated how speaker’s comfort and vocal effort were affected during short speech tasks in four different room acoustic configurations. Voice recordings of the speech tasks and self-evaluations of the speaker’s comfort were collected from 15 participants in four room acoustic configurations as part o
Speech signal decoding relies on both cognitive performance and the ability to perceive the acoustic signal in sufficient detail. In everyday communication, natural speech is often rapid, spatially and spectrally complex, and accompanied by noise. The brain generates predictions to cope with the complex nature of the auditory signal in speech perception. Anticipatory coarticulation is a natural pa
