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Biomedical research projects involving multiple partners from public and private sectors require coherent internal governance mechanisms to engender good working relationships. The DIRECT project is an example of such a venture, funded by the Innovative Medicines Initiative Joint Undertaking (IMI JU). This paper describes the data access policy that was developed within DIRECT to support data acce

For more than 30 years polyimides (PA) have been one of the main polymers for the fabrication of thin film composite membranes. Several researchers have assessed the main fabrication variables that influence the final structure of the polyamide layers including monomer concentration, solvents, additives in aqueous and organic phases and type of support to mention few [1,2]. However, few studies ha

This review describes the history, development, and evolution of cell-based replacement therapy for Parkinson's disease (PD), from the first pioneering trials with fetal ventral midbrain progenitors to future trials using stem cells as well as reprogrammed cells. In the spirit of Tom Isaacs, the review takes parallels to the storyline of Star Wars, including the temptations from the dark side and

Using satellite remote sensing data for observing vegetation seasonality is an important approach to estimate phenology and carbon uptake of land vegetation. The successful launch of Sentinel-2B in 2017 initiated full operation of the Sentinel-2 twin satellites, and they now provide 10 - 60 m spatial resolution satellite data at 5 days temporal resolution worldwide, releasing approximately 3.2 TB

In evaluating the effectiveness of a road safety treatment, the regression to the mean phenomenon is a cause for concern because of a possible overestimation of benefits. Therefore, Bayesian approaches are usually suggested as the most appropriate methodologies for before—after studies as they account for regression to the mean effects. The empirical Bayes (EB) methodology examines the estimation

Allergic rhinitis (AR) poses a global health problem and can be challenging to treat. Many of the current symptomatic treatments for AR have been available for decades, yet there has been little improvement in patient quality of life or symptom burden over the years. In this review, we ask why this might be and explore the pathophysiologica

To estimate in gynecologically asymptomatic postmenopausal women with and without hormone replacement therapy (HRT) the prevalence at transvaginal ultrasound examination of 1) endometrial thickness ≥5.0mm, 2) intrauterine focal lesions if endometrial thickness ≥5.0mm, and 3) premalignant and malignant changes in the endometrium if endometrial thickness is ≥5.0mm and intrauterine focal lesions are

OBJECTIVES: To determine the agreement between transvaginal ultrasound examinations performed before and at saline contrast sonohysterography (SCSH) with regard to number, size and shape of Cesarean section (CS) scar defects. METHODS: In all, 108 women underwent transvaginal ultrasound examination with SCSH at least 6 months after CS: 68 had undergone one CS, 32 two CSs and eight women had undergo

This study is motivated by the need to know the characteristics of the learning processes in tongue-computer interaction and to obtain a useful insight to a better design of the tongue-computer interface for computer text input. Tongue-typing can be a good alternative to hand input methods for physically disabled individuals or tasks where hand-typing is not possible. In order to evaluate the proc

Child mortality because of infectious preventable diseases is a global tragedy. Millions of children die in vain every year. This thesis presents a sincere effort to decrease child mortality on given reason. The servitized Business Information System (BIS) named VacSam provides unique vaccination recommendations to any child thus service orienting a part of the Swedish vaccination activity. Design

Den 27 oktober 2006 meddelade den engelska appellationsdomstolen (UK Court of Appeal) ett vägledande avgörande i de s.k. Aerotel/Macrossan-avgörandena. Domen relaterade till två mål som berörde tolkningen av det patenterbara området enligt sektion 1 (2) i den engelska patentlagen (Patent Act 1977), vilken motsvarar art. 52 i den Europeiska Patentkonventionen (EPC). Det första målet gällde ett isra

Nowadays, many evacuation models exist in the market, and new models are continuously released with new features. How to assess the usability and reliability of model results becomes an issue for both developers and users. Therefore, verification and validation (V&V) protocols were introduced in the assessment process of evacuation models. To conduct V&V of a model, a widely accepted test

Despite a common colonial past under the British empire, Singapore and Malaysia have experienced vastly different development paths since independence. While Singapore has one of the highest per capita incomes in the world today, Malaysia’s economy remains a mere third of that of Singapore’s. Despite the economic disparity between the two countries, the newly available data on well-being, as prese

The realisation of the inner market meant that all border controls between the Member States of the European Community were to disappear, so that the four freedoms, workers, capital, services and goods, could cross the borders without problems. But in order to keep the security in a Community with no borders, the external border controls had to be strengthened. This was necessary to keep out drugs