Background: It is unclear if a non-radical diagnostic biopsy entails a higher risk for metastasis and poorer survival for patients with cutaneous head and neck melanoma (cHNM). Aims/objectives: To assess whether or not initial diagnostic biopsy modality and radicality (clear, positive, or narrow histopathological margins) influence recurrence and survival in patients with cHNM. Materials and metho

Over the last decade, representations of the rainbow were repeatedly disputed in Poland, revealing the country’s ongoing socio-political changes and its drift away from the generally liberal and secular values of the European mainstream. These cases show a political growth and an increasing social diffusion of Polish ‘national paleoconservatism.’ The aim of this article is to (1) discuss the intel

The optical and electrochemical properties of a series of polyoxometalate (POM) oxoclusters decorated with two bodipy (boron-dipyrromethene) light-harvesting units were examined. Evaluated here in this polyanionic donor-acceptor system is the effect of the solvent and associated counterions on the intramolecular photoinduced electron transfer. The results show that both solvents and counterions ha

In this paper, an aerosol-based process is proven for imparting antibacterial property to textiles. Nanoparticles of copper and silver are produced by means of glow discharge between two electrodes in nitrogen at atmospheric pressure and passed through fabrics of cotton and polyester which act as filter media. The bactericidal performance of the nanofinished fabrics is assessed against Gram-positi

In this paper we propose a design methodology to partition dataflow applications on a multi clock domain architecture. This work shows how starting from a high level dataflow representation of a dynamic program it is possible to reduce the overall power consumption without impacting the performances. Two different approaches are illustrated, both based on the post-processing and analysis of the ca

Decision-making is central to Software Product Management (SPM) and includes deciding on requirements priorities and the content of coming releases. Several algorithms for prioritization and release planning have been proposed, where humans with or without machine support enact a series of steps to produce a decision outcome. Instead of applying some specific algorithm to find an acceptable soluti

Parser generators are an indispensable tool for rapid language devel- opment. However, they often fall short of the finesse of a hand-crafted parser, built with the language semantics in mind. One area where generated parsers have pro- vided unsatisfactory results is that of error recovery. Good error recovery is both natural, giving recovery suggestions in line with the intention of the programme

Background: Emergency Department crowding is associated with increased morbidity and mortality but no measure of crowding has been validated in Sweden. We have previously derived and internally validated the Skåne Emergency Department Assessment of Patient Load (SEAL) score as a measure of crowding in Emergency Departments (ED) in a large regional healthcare system in Sweden. Due to differences in

An increased incidence of narcolepsy type 1 (NT1) was observed in Scandinavia following the 2009–2010 influenza Pandemrix vaccination. The association between NT1 and HLA-DQB1*06:02:01 supported the view of the vaccine as an etiological agent. A/H1N1 hemagglutinin (HA) is the main antigenic determinant of the host neutralization antibody response. Using two different immunoassays, the Luciferase I

Alternative ways to prevent and treat infectious diseases are needed. Previously, we identified a fungal peptide, NZX, that was comparable to rifampicin in lowering M. tuberculosis load in a murine tuberculosis (TB) infection model. Here we assessed the potential synergy between this cationic host defence peptide (CHDP) and the current TB drugs and analysed its pharmacokinetics. We found additive

n this paper, we introduce a constraint programming-based approach for the optimization of area and of reconfiguration time for communication networks for a class of regular 2D reconfigurable processor array architectures. For a given set of different algorithms the execution of which is supposed to be switched upon request at run-time, we provide static solutions for the optimal routing of data b

Background: Patients diagnosed with metastatic breast cancer have poor outcome with a median survival of approximately 2 years. While novel therapeutic options are urgently needed, the great majority of breast cancer research has focused on the primary tumor and less is known about metastatic breast cancer and the prognostic impact of the metastatic tumor microenvironment. Here we investigate the

Background: The COVID-19 pandemic has rapidly led to some of the most revolutionary changes in private and professional life around the world. While the extent and duration of these changes are not certain, they have already had a great impact on travel patterns. This is also the case in Sweden, despite its relatively liberal approach to restrictions, which relies on voluntary measures such as soc

Enlargements of distal airspaces can indicate pathological changes in the lung, but accessible and precise techniques able to measure these regions are lacking. Airspace Dimension Assessment with inhaled nanoparticles (AiDA) is a new method developed for in vivo measurement of distal airspace dimensions. The aim of this study was to benchmark the AiDA method against quantitative measurements of di