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Freely available convolutional neural network-based quantification of PET/CT lesions is associated with survival in patients with lung cancer

Background: Metabolic positron emission tomography/computed tomography (PET/CT) parameters describing tumour activity contain valuable prognostic information, but to perform the measurements manually leads to both intra- and inter-reader variability and is too time-consuming in clinical practice. The use of modern artificial intelligence-based methods offers new possibilities for automated and obj

The Design of 3D-Printed Polylactic Acid–Bioglass Composite Scaffold : A Potential Implant Material for Bone Tissue Engineering

Bio-based and patient-specific three-dimensional (3D) scaffolds can present next generation strategies for bone tissue engineering (BTE) to treat critical bone size defects. In the present study, a composite filament of poly lactic acid (PLA) and 45S5 bioglass (BG) were used to 3D print scaffolds intended for bone tissue regeneration. The thermally induced phase separation (TIPS) technique was use

Mass Transport of Lignin in Confined Pores

A crucial step in the chemical delignification of wood is the transport of lignin fragments into free liquor; this step is believed to be the rate-limiting step. This study has investigated the diffusion of kraft lignin molecules through model cellulose membranes of various pore sizes (1–200 nm) by diffusion cells, where the lignin molecules diffuse from donor to acceptor cells through a membrane,

How Can Sewage Sludge Use in Sustainable Tunisian Agriculture Be Increased?

In recent years, farmers in Beja, an agricultural governorate in northwestern Tunisia, have expressed their willingness to use urban sewage sludge as agricultural fertilizer, especially with the unavailability of chemical fertilizers and the soil type of the region that is poor in organic matter. However, there is an imbalance between the important farmers’ demand versus the limited quantity of sl

Hydraulic Modeling and Remote Sensing Monitoring of Floodhazard in Arid Environments—A Case Study of Laayoune City in Saquia El Hamra Watershed Southern Morocco

Morocco often faces significant intense rainfall periods that can generate flash floods and raging torrents, causing serious damage in a very short period of time. This study aims to monitor wetland areas after a flash-flood event in an arid region, Saquia El hamra Saharan of Morocco, using a technique that combines hydraulic modeling and remote sensing technology, namely satellite images. The hyd

Implementation of physical activity on prescription for children with obesity in paediatric health care (IMPA) : protocol for a feasibility and evaluation study using quantitative and qualitative methods

Background: Physical inactivity is a main cause of childhood obesity which tracks into adulthood obesity, making it important to address early in life. Physical activity on prescription (PAP) is an evidence-based intervention that has shown good effect on physical activity levels in adults, but has not been evaluated in children with obesity. This project aims to evaluate the prerequisites, determ

Diagnostic yield is dependent on monitoring duration. Insights from a full-disclosure mobile cardiac telemetry system

Background: Despite the advancement of electrocardiogram (ECG) monitoring methods, the most important factor influencing diagnostic yield (DY) may still be monitoring duration. Ambulatory ECG monitoring, typically with 24–48 hours duration, is widely used but may result in underdiagnosis of rare arrhythmias. Aims: This study aimed to examine the relationship between the DY and monitoring duration

Monte Carlo modelling of a compact CZT-based gamma camera with application to 177Lu imaging

Background: Semiconductor gamma-camera systems based on cadmium zinc telluride (CZT) detectors present new challenges due to an energy-response that includes effects of low-energy tailing. In particular, such energy tails produce effects that need to be considered when imaging radionuclides with multiple emissions such as 177Lu. Monte Carlo simulation can be used to investigate the behaviour of su

Choral Singing Enriches Everyday Life for People With Mild to Moderate Dementia and Their Family Caregivers

Dementia causes substantial suffering for affected persons and their family care-givers. Because no cure is available, it is important to investigate how alternative therapies can improve life for these individuals. For the current study, persons with dementia (PwD) were recruited from a specialized Memory Clinic in Sweden to en-gage in a choral singing intervention for 1 hour per week for four se

GFAP and S100B : What You Always Wanted to Know and Never Dared to Ask

Traumatic brain injury (TBI) is a major global health issue, with outcomes spanning from intracranial bleeding, debilitating sequelae, and invalidity with consequences for individuals, families, and healthcare systems. Early diagnosis of TBI by testing peripheral fluids such as blood or saliva has been the focus of many research efforts, leading to FDA approval for a bench-top assay for blood GFAP

InSegtCone : interactive segmentation of crystalline cones in compound eyes

Background: Understanding the diversity of eyes is crucial to unravel how different animals use vision to interact with their respective environments. To date, comparative studies of eye anatomy are scarce because they often involve time-consuming or inefficient methods. X-ray micro-tomography (micro-CT) is a promising high-throughput imaging technique that enables to reconstruct the 3D anatomy of

Association of Daily Eating Duration and Day-To-Day Variability in the Timing of Eating With Fatal Cancer Risk in Older Men

Meal timing has significant effects on health. However, whether meal timing is associated with the risk of developing and dying of cancer is not well-researched in humans. In the present study, we used data from 941 community-dwelling men aged 71 years who participated in the Uppsala Longitudinal Study of Adult Men to examine the association of meal timing with cancer morbidity and fatal cancer. T

An Algorithm for Strategic Continuation or Restriction of Asthma Medication Prior to Exercise Challenge Testing in Childhood Exercise Induced Bronchoconstriction

Exercise induced bronchial (EIB) constriction is a common and highly specific feature of pediatric asthma and should be diagnosed with an exercise challenge test (ECT). The impact of EIB in asthmatic children's daily lives is immense, considering the effects on both physical and psychosocial development. Monitoring childhood asthma by ECT's can provide insight into daily life disease burden and th