SIK2 (salt-inducible kinase 2) is a member of the AMPK (AMP-activated protein kinase) family of kinases and is highly expressed in adipocytes. We investigated the regulation of SIK2 in adipocytes in response to cellular stimuli with relevance for adipocyte function and/or AMPK signalling. None of the treatments, including insulin, cAMP inducers or AICAR (5-amino-4-imidazolecarboxamide riboside), a

The author examines the intriguing mention of “those who curse Yamm” and “rouse Leviathan” in Job 3:8, and tries to relate these expressions to Near Eastern religious history. The old assumption that two texts inscribed on Aramaic incantation bowls indicate the full background of these expressions is challenged, and further evidence is sought in texts such as the Enuma Elish, the Gnosticizing “Hym

There is an urgent need for biomarkers in plasma to identify Alzheimer's disease (AD). It has previously been shown that a signature of 18 plasma proteins can identify AD during pre-dementia and dementia stages (Ray et al, Nature Medicine, 2007). We quantified the same 18 proteins in plasma from 174 controls, 142 patients with AD, and 88 patients with other dementias. Only three of these proteins

INTRODUCTION: Cluster headache (CH) is a primary headache by definition not caused by any known underlying structural pathology. However, symptomatic cases have been described. The evaluation of CH is an issue unresolved. CASE REPORT: A 41-year-old man presented with a 3-month history of side-locked attacks of excruciating severe stabbing and boring right-sided pain located in the temple and the

Kallander H. 2011. Fishing flocks of Great Crested Grebes Podiceps cristatus consist of breeding birds. Ardea 99: 232-234. This note corrects a statement made in an earlier note on flock-fishing Great Crested Grebes Podiceps cristatus at the South Swedish Lake Krankesjon, namely that the flocks presumably consisted mainly of non-breeders. This has been proved wrong. The majority come from a loose

Galloway-Mowat syndrome (GMS) is a rare autosomal recessive disorder characterized by early onset nephrotic syndrome and microcephaly with various anomalies of the central nervous system. GMS likely represents a heterogeneous group of disorders with hitherto unknown genetic etiology. The clinical phenotype to some extent overlaps that of Pierson syndrome (PS), which comprises congenital nephrotic

A building-integrated multifunctional PV/T solar window has been developed and evaluated. It is constructed of PV cells laminated on solar absorbers placed in a window behind the glazing. To reduce the cost of the solar electricity, tiltable reflectors have been introduced in the construction to focus radiation onto the solar cells. The reflectors render the possibility of controlling the amount o

Using the latest available data, this brief article attempts to provide the first regional decomposition analysis of CO2 emissions from fuel combustion. Covering eight regions of the world, determinants are estimated in relative and absolute terms for the period 1971-2010. We use the unparalleled 2010 global surge in CO2 emissions as a reference and entry point for the analysis. Overall, results s

A discussion about biographical methods and a comparision between my biography of Oscar I, swedish king 1844-1859, and my biographies of women in the 1900-th century.

Recension av Carina Renander; Förförande fiktion eller historieförmedling? Arn-serien, historiemedvetande och historiedidaktik

Edge aliasing continues to be one of the most prominent problems in real-time graphics, e.g., in games. We present a novel algorithm that uses shared memory between the GPU and the CPU so that these two units can work in concert to solve the edge aliasing problem rapidly. Our system renders the scene as usual on the GPU with one sample per pixel. At the same time, our novel edge aliasing algorithm

Hypoxia, or deficient oxygen levels, is an inherent feature of rapidly expanding tumor tissue. In order to survive in the hostile, hypoxic environment and to restore the supply of oxygen and nutrients tumor cells activate a variety of adaptive mechanisms. Among them, hypoxia-induced angiogenesis, i.e. the formation of tumor blood vessels from pre-existing vasculature, has proved to be of critical

Popular Abstract in Swedish Tack vare den snabba tekniska och digitala utvecklingen under senare år har tomosyntes etablerats som ett nytt och spännande verktyg inom röntgendiagnostiken. Metoden är en vidareutveckling av gammaldags tomografi (skiktröntgen), men är lättare att utföra, ger bättre bilder och dessutom är stråldosen betydligt lägre. Vid tomosyntes gör röntgenröret ett svep över den krThe aims of this thesis were to investigate whether chest tomosynthesis might be used in pulmonary cystic fibrosis, to design and validate a tomosynthesis scoring system, and to determine the effective dose from chest tomosynthesis in children. In a prospective study starting in 2008 clinical chest radiography or computed tomography (CT) were supplemented with a tomosynthesis examination of the l

Abstract in Undetermined In this paper, the news aggregator GoogleNews is used to assess the impact ofworldwide news on the volatility of the Chinese stock market. Although we find a strong link between the global stock market volatility and the amount of stock market-related news available worldwide, the link between the Chinese stock market and the same set of worldwide news is found to be much

Ordered nanoporous structures are among the most fascinating and industrially important materials currently in use. The archetypal zeolite material has now been joined by an eclectic array of new structures that exhibit porosity over a wide range of length scales and with order/disorder expressed in a multitude of ways. This raises the bar in terms of characterization and extends a real challenge

We present RF characterization of vertical gateall- around InAs nanowire MOSFETs integrated on Si substrates with peak f(t) = 142 GHz and f(max) = 155 GHz, representing the record for vertical nanowire transistors. The devices has an L-g approximate to 150 nm with a g(m)=700 mS/mm for a nanowire diameter of 38 nm and an EOT = 1.4 nm. The high values of f(t) is achieved through electron beam lithog