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The ability to image specific areas of the body is crucial for developing novel, non-invasive medical approaches. Nanocarriers designed for this purpose should have minimal cytotoxicity to accurately reveal internalization mechanism while also allowing for tunable localization within the cells through compositional adjustments. Cubosomes have been widely studied as carriers for imaging agents. How
5G antennas for vehicular connectivity are often mounted on the car roof to optimize signal reception. The trend of replacing metal roof with glass in modern cars opens an opportunity for embedding the 5G antennas inside the glass roof. In this work, we compare the channel gains of reference dipole, and loop antennas positioned at the roof center. Then, by considering the requirements of glass int
Om ett stelefynd från det ptolemaiska Egypten (Ptolemaios III:s tid).
This article engages critically with one of the more original and thought-provoking efforts of recent years to respond philosophically to the current predicament of the world: Thomas Lynch’s 2019 study Apocalyptic Political Theology. While agreeing with Lynch that the urgency of our times calls for more radical approaches than cautious dialogue or reformist adaptation, it nonetheless argues that a
INTRODUCTION: We investigated the natural history of the relationship between PSA at age 60 and lifetime risk of prostate cancer death in an unscreened cohort followed for 40 years, the Malmö Preventive Project. We also investigated whether percent free PSA could risk-stratify men with low PSAs.METHODS: The cohort included 1162 men aged 58-62 at blood draw in 1981-82, with 1151 deaths by December
IMPORTANCE: Repeating a prostate-specific antigen (PSA) test after an elevated measurement is a guideline-recommended component of the prebiopsy workup. However, it is unclear whether certain patients can be exempted from repeat PSA testing and proceed directly to further workup.OBJECTIVE: To determine yearly PSA variability and implications of repeating an elevated PSA in the Prostate, Lung, Colo
INTRODUCTION: Inflammation is integral to wound healing; yet, its dynamics in normally healing epidermal wounds are not fully characterized. To this end, we analyzed longitudinal wound fluid samples collected from epidermal suction blister wounds in healthy volunteers.MATERIALS AND METHODS: A total of 48 control wounds were induced by suction blister method in 24 healthy volunteers-1 on each thigh
The emergence of antibiotic resistance necessitates effective strategies for evaluating antimicrobial agents. Bioluminescent bacteria, either naturally occurring or engineered with modified reporter genes like bacterial luciferase, provide real-time assessment of bacterial viability through light emission. We investigated the antibacterial effects of cefotaxime and doxycycline using bioluminescent
Chronic obstructive pulmonary disease (COPD) and asthma both involve inflammation and structural changes in the peripheral airways that are not detectable with current standard tools such as spirometry. Accurate and sensitive assessment of lung function is crucial for early diagnosis, monitoring disease progression, and guiding appropriate treatment.The overall aim of this thesis was to investigat
BackgroundAirway hyperresponsiveness (AHR), a key feature of asthma, leads to airway narrowing in response to bronchoconstrictor stimuli. Notably, AHR is also observed in individuals with chronic obstructive pulmonary disease (COPD). The Mannitol challenge test is an indirect method to assess airway hyperresponsiveness.ObjectiveThe primary aim of this study was to explore airway hyperresponsivenes
After the clinical implementation of amyloid-β-targeting therapies for people with cognitive impairment due to Alzheimer's disease (AD), there is an urgent need to efficiently identify this patient population in primary care. Therefore, we created a brief and self-administered digital cognitive test battery (BioCog). Based on its sub-scores, a logistic regression model was developed in a secondary
The polar lipids in oat grains are crucial due to their biological functions, nutritional quality, potential use in food flavour and processing, the protection they provide against biotic and abiotic stresses, and their ability to act as cellular signalling molecules. In this study, we present novel findings about the impacts of fertilization and field management on oat polar lipid and fatty acid
Objectives:To determine the cumulative live birth rate (CLBR) under three consecutive in vitro fertilisation (IVF) treatments in women with endometriosis and/or adenomyosis.Methods:A prospective cohort study of 1035 women aged 25–≤39 years undergoing up to three consecutive IVF treatments between January 2019 and April 2024. All women underwent an advanced transvaginal ultrasound examination prior
STUDY QUESTIONDoes endometriosis and/or adenomyosis, diagnosed using the International Deep Endometriosis Analysis (IDEA) group and the Morphological Uterus Sonographic Assessment (MUSA) group revised definitions, impact cumulative live birth rates (CLBR) after three consecutive IVF or ICSI treatments?SUMMARY ANSWERWomen with endometriosis and/or adenomyosis, as diagnosed using transvaginal ultras
The urgency of addressing the harms of AI chatbots was underscored in the recent US Senate Judiciary Committee hearing, “Examining the Harm of AI Chatbots.” During the hearing, parents of children recounted the harrowing stories of AI chatbot-influenced mental health emergencies, including self-harm and death, harms that were never inevitable. Instead, they were predictable consequences of a lax r
BACKGROUND: While patients with post-COVID syndrome (PCS) suffer from cognitive deficits few studies directly compare patients with PCS to subjects recovered after an infection with the 'Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)'.OBJECTIVES: To investigate cognitive performance adjusting for age, increasing body-mass-index (BMI), smoking, years of education, gender and hospitali
