A Polar Cannabinoid from Cannabis sativa var. Carma
The aerial parts of Cannabis saliva var. Carma afforded a novel polar cannabinoid whose structure was established as rac-6',7'-dihydro,6',7'-dihydroxycannabigerol (carmagerol, 1) on the basis of spectroscopic data and semisynthesis from cannabigerol (2a). The dihydroxylation of the omega-double bond was detrimental to the anti-bacterial activity.