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Measurement of quarkonium production in proton–lead and proton–proton collisions at 5.02TeV with the ATLAS detector

The modification of the production of J/ ψ, ψ(2 S) , and Υ(nS) (n= 1 , 2 , 3) in p+Pb collisions with respect to their production in pp collisions has been studied. The p+Pb and pp datasets used in this paper correspond to integrated luminosities of 28nb-1 and 25pb-1 respectively, collected in 2013 and 2015 by the ATLAS detector at the LHC, both at a centre-of-mass energy per nucleon pair of 5.02

Measurement of the dependence of transverse energy production at large pseudorapidity on the hard-scattering kinematics of proton–proton collisions at √s=2.76 TeV with ATLAS

The relationship between jet production in the central region and the underlying-event activity in a pseudorapidity-separated region is studied in 4.0 pb−1 of s=2.76 TeV pp collision data recorded with the ATLAS detector at the LHC. The underlying event is characterised through measurements of the average value of the sum of the transverse energy at large pseudorapidity downstream of one of the pr

MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo

There is a high quest for novel therapeutic strategies to enhance recovery after stroke. MicroRNA-124 (miR-124) has been described as neuroprotective and anti-inflammatory molecule. Moreover, miR-124 is a well described enhancer of adult neurogenesis that could offer potentially beneficial effects. Herein, we used miR-124-loaded nanoparticles (miR-124 NPs) to evaluate their therapeutic potential i

Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder

Major depressive disorder (MDD) has been linked to mitochondrial defects, which could manifest in mitochondrial DNA (mtDNA) polymorphisms or mutations. Additionally, copy number of mtDNA (mtDNA-cn) can be quantified in peripheral blood mononuclear cells (PBMC)s, indirectly reflecting cellular energetics, or in the circulating cell-free mtDNA (ccf-mtDNA) levels, which may reflect a fraction of the

Anisotropy enhanced X-ray scattering from solvated transition metal complexes

Time-resolved X-ray scattering patterns from photoexcited molecules in solution are in many cases anisotropic at the ultrafast time scales accessible at X-ray free-electron lasers (XFELs). This anisotropy arises from the interaction of a linearly polarized UV-Vis pump laser pulse with the sample, which induces anisotropic structural changes that can be captured by femtosecond X-ray pulses. In this

In situ characterization of the deposition of anatase TiO2 on rutile TiO2(110)

Growing additional TiO2 thin films on TiO2 supstrates in ultrahigh vacuum (UHV)-compatible chambers have many applications for sample preparation, such as smoothing surface morphologies, templating, and covering impurities. However, there has been little study into how to control the morphology of TiO2 films deposited onto TiO2 supstrates, especially using atomic layer deposition (ALD) precursors.

Hög diabetesrisk bland icke-västerländska invandrare : Riktad och strukturerad prevention behövs

Political instability the last decades has forced millions of people to migrate from their homelands. In Sweden today, 1.6 million are born abroad, of which the largest immigrant groups originate from the Middle East. Immigrants from these areas represent high risk populations for type 2 diabetes with prevalence of type 2 diabetes twice as high compared to the native Swedish population. The mechanPolitical instability the last decades has forced millions of people to migrate from their homelands. In Sweden today, 1.6 million are born abroad, of which the largest immigrant groups originate from the Middle East. Immigrants from these areas represent high risk populations for type 2 diabetes with prevalence of type 2 diabetes twice as high compared to the native Swedish population. The mechan

FemtoMAX - An X-ray beamline for structural dynamics at the short-pulse facility of MAX IV

The FemtoMAX beamline facilitates studies of the structural dynamics of materials. Such studies are of fundamental importance for key scientific problems related to programming materials using light, enabling new storage media and new manufacturing techniques, obtaining sustainable energy by mimicking photosynthesis, and gleaning insights into chemical and biological functional dynamics. The Femto

Innovation for biorefineries – Networks, narratives, and new institutions for the transition to a bioeconomy

I omställningen till en mer hållbar bioekonomi har mycket fokus legat på utvecklingen av biobränslen. När det gäller innovation och utveckling av kemikalier och andra produkter släpar utvecklingen efter av flera orsaker, vilket visas i denna avhandling.Forskningen visar att det nuvarande systemet är inlåst i ett fossilberoende av flera olika orsaker, både tekniska, organisatoriska och materiella. The transition to a bioeconomy is dependent on transformative changes to technologies, organisations, and institutions, which jointly can be described as a socio-technical change. The thesis contributes to the understanding of how the transition is shaped by expectations on and collaborations for innovation forbiorefineries, which can produce chemicals, fuels, and materials needed in a bioeconomy.

The pathogenetic role of β-cell mitochondria in type 2 diabetes

Mitochondrial metabolism is a major determinant of insulin secretion from pancreatic β-cells. Type 2 diabetes evolves when β-cells fail to release appropriate amounts of insulin in response to glucose. This results in hyperglycemia and metabolic dysregulation. Evidence has recently been mounting that mitochondrial dysfunction plays an important role in these processes. Monogenic dysfunction of mit