Sökresultat

Filtyp

Din sökning på "*" gav 534239 sökträffar

Exercise physiology and cardiac function. Aspects on determinants of maximal oxygen uptake

Although the athlete's heart has been of interest for over 100 years, further characterization of the athletes heart is needed in order to understand how training affects cardiac dimensions and function. Few studies have investigated the effects of training in female athletes and few have compared males and females. Therefore, the aim of this thesis was to characterize the physiologically enlarged

A model-based methodology for the analysis and design of atomic layer deposition processes-Part I: Mechanistic modelling of continuous flow reactors

This paper presents the development of an experimentally validated model that mechanistically comprehends the complex interaction between the gas-phase fluid dynamics, the mass transport of individual species, and the heterogeneous gas-surface reaction mechanism in a continuous cross-flow atomic layer deposition (ALD) reactor. The developed ALD gas-surface reaction mechanism, purely based on conse

Palladium(II)-Catalyzed Oxidative Cyclization of Allylic Tosylcarbamates: Scope, Derivatization, and Mechanistic Aspects

A highly selective oxidative palladium(II)-catalyzed (Wacker-type) cyclization of readily available allylic tosylcarbamates is reported. This operationally simple catalytic reaction furnishes tosyl-protected vinyl-oxazolidinones, common precursors to syn-1,2-amino alcohols, in high yield and excellent diasteroselectivity (>20:1). It is demonstrated that both stoichiometric amounts of benzoquinone

The Pancreatic Tumour Microenvironment. Influence by macrophages and glucose levels on tumourigenesis.

Popular Abstract in Swedish Vad har Nobelpristagaren i medicin 2011, huvudpersonen i Dirty Dancing, en av världens främsta tenorer och grundaren av Apple gemensamt? De drabbades alla av olika typer av bukspottkörtelcancer. Bukspottkörtelcancer är en av våra värsta cancerformer. Den drabbar årligen ca 1000 personer och 5-årsöverlevnaden är lägre än 5%. Den enda chansen till bot är via kirurgi, men Pancreatic cancer is the fourth cause of cancer-related death with a 5-year survival rate less than 5%. Two of the risk factors are chronic pancreatitis and type 2 diabetes (T2D), which are believed to promote the tumour progression. Pancreatic cancer and its tumour microenvironment is characterised by a dense stroma, immune cell infiltration and poor vascularisation. This creates a favourable env

Association of estrogen receptor-alpha A908G (K303R) mutation with breast cancer risk

Genetic mutations in premalignant breast lesions may have a role in malignancy progression or influence the behavior of subsequent disease. A point mutation in estrogen receptor-alpha (ER-&ALPHA) as A908G (Lys303 -> Arg) was originally involved to hypersensitive to estrogen breast hyperplasia. We detected this mutation among Iranian women with invasive breast cancer. A population-based case-co

Rheumatoid Arthritis: Body Composition, Bone Loss, and Mortality

Early rheumatoid arthritis (RA) patients (disease duration ≤1 year, n=165) were recruited 1995-2001 and followed systematically clinically and with dual energy X-ray absorptiometry (DXA) over 2 years and compared to age- and gender-matched controls. Baseline arm and leg lean mass were decreased in RA patients in both genders and body mass index and truncal fat distribution were increased in female

Approximate Optimal Periodogram Smoothing for Cepstrum Estimation using a Penalty Term

The cepstrum of a random process is useful in many applications. The cepstrum is usually estimated from the periodogram. To reduce the mean square error (MSE) of the estimator, the periodogram may be smoothed with a kernel function. We present an explicit expression for a kernel function which is approximatively MSE optimal for cepstrum estimation. A penalty term has to be added to the minimizatio

Identification of core T cell network based on immunome interactome.

Data-driven studies on the dynamics of reconstructed protein-protein interaction (PPI) networks facilitate investigation and identification of proteins important for particular processes or diseases and reduces time and costs of experimental verification. Modeling the dynamics of very large PPI networks is computationally costly.

High Critical-Current Superconductor-InAs Nanowire-Superconductor Junctions

We report on the fabrication of InAs nanowires coupled to superconducting leads with high critical current and widely tunable conductance. We implemented a double lift off nanofabrication Method to get very short nanowire devices with Ohmic contacts. We observe very high critical. currents of up to 800 nA in a wire with a diameter of 80 nm. The current- voltage characteristics of longer and suspen

Light triggered release of solutes from covalent DNA gels

DNA gels were prepared by cross-linking and were examined with respect to the release of DNA as well as macromolecular cosolutes introduced into the gels. In particular the effect of exposure to ultraviolet light was examined for these photodegradable gels. Different cross-linker densities (0.5%, 1%, 3% and 5% ethylene glycol diglycidyl ether) of the DNA gels were used. Network mesh size and the e

Anthropogenic aerosol effects on convective cloud microphysical properties in southern Sweden

In this study, we look for anthropogenic aerosol effects in southern Scandinavia's clouds under the influence of moderate levels of pollution and relatively weak dynamic forcing. This was done by comparing surface aerosol measurements with convective cloud microphysical profiles produced from satellite image analyses. The results show that the clouds associated with the anthropogenic-affected air

Dissipative particle dynamics approach for nano-scale membrane structure reconstruction and water diffusion coefficient estimation

The membrane is often considered as the heart of the proton exchange membrane fuel cell (PEMFC), and it is of pivotal importance for the involved transport phenomena and performance of the entire PEMFC. The Nafion(R) membrane is the most commonly used type of membrane in PEMFCs. In this paper, the nano-scale structure of the Nafion(R) membrane is reconstructed using dissipative particle dynamics.