Popular Abstract in Swedish Graden av genetisk variation inom och mellan olika populationer bestäms av balansen mellan tre faktorer: naturligt urval, slumpmässig genetisk drift och genflöde. Genom studier av genetisk variation är det möjligt att dra slutsatser om t ex selektionstryck på olika alleler (genvarianter), arters spridningsvägar till nya platser, tid sedan etablering och graden av släktsIn this thesis I present studies concerning genomic diversity and genetic heterogeneity as well as the evolution and maintenance of genetic variation at a specific immune defence gene in Atlantic salmon (Salmo salar, L.). I here present data on nucleotide diversity showing that human activities as well as different post-glacial colonisation events have had considerable effects on the genomic diver

We offer an analysis of perceptual intersubjectivity (PI) in terms of two types (symmetric and asymmetric) and three levels: synchronous (SPI), coordinated (CPI) and reciprocal (RPI), defined on the basis of the observable behavior of the participants in a study of (non-verbal) social interaction. We hypothesize that the three levels constitute stages in the development and possibly evolution of h

On the request of Dr Daniel Hellström (Stockholm Water AB), IEA was asked to perform a preliminary investigation of two alternatives for anaerobic digestion operation at Henriksdal’s WWTP in Stockholm, Sweden. The system should be analysed based on parallel or series operation of two existing AD reactors. Moreover, the input load should be based on the current situation and a future scenario (esti

This study investigated cold weather safety footwear and the possible thermal effects of steel toe caps in footwear. Two boot models were manufactured and used in two variants - with (As and Ws) and without (An and Wn) steel toe cap. The boot insulation was measured with an artificial, heated foot (AHF). Experiments with 6 male subjects with boots Ws and Wn consisted of sitting for 60 minutes at -

Popular Abstract in Swedish Oberoende av om det är i ett samhälle, datornätverk eller organen i en mänsklig kropp, så är behovet av kommunikation stort i en komplex miljö. Eftersom den komplicerade människokroppen är beroende av kommunikation för att reglera funktioner, skickas otaliga mängder signaler oavbrutet. För att signalerna skall vara meningsfulla så måste de kunna tas emot och behandlas. Intercellular communication is of crucial importance in regulating physiology and G-protein coupled receptors (GPCRs) have evolved as an important mechanism in this process. Of the approximately 800 human GPCRs, about 160 are still considered to be “orphan” receptors for which an endogenous ligand remains to be identified. Since an estimated 50% of all clinical drugs act on 30 known GPCRs, the rem