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Granulocyte chemotactic protein 2 (GCP-2)/CXCL6 is a CXC chemokine expressed by macrophages and epithelial and mesenchymal cells during inflammation. Through binding and activation of its receptors (CXCR1 and CXCR2), it exerts neutrophil-activating and angiogenic activities. Here we show that GCP-2/CXCL6 itself is antibacterial. Antibacterial activity against gram-positive and gram-negative pathog

En av vintergatans största stjärnor uppvisar ett märkligt beteende. Om ett år sker nästa utbrott.

Popular Abstract in Swedish Ämnet för avhandlingen är verbets morfologiska och stilistiska variation i den grekiska versromanen Erotokritos, ett av de främsta exemplen på den kretensiska renässansdiktningen. Undersökningen utgår från de i dikten förekommande verbformernas morfologiska variation, både vad avser stammar, ändelser och augment. Undersökningen koncentreras på de imperfektiva verbformerThe aim of the present study is to examine the polytypia (morphological variation) and semantic differentiations of the verb in Vitsentzos Kornaros' Erotokritos, to understand how these shape poetic style. We examine the stems and the endings in the imperfective active forms. Moreover, we investigate the augmented forms because at an early stage we found that Kornaros employs a degree of poetic li

The performance of LNAs and VCOs is of large importance to the complete wireless communications system. To achieve sufficient performance in microwave applications, LNAs and VCOs have therefore up to now mostly been manufactured in advanced and expensive semiconductor technologies. In this thesis it is shown, however, that by using a standard CMOS technology, combined with different packaging and

One complication in implant dentistry is the implant periapical lesion-IPL--which is a lesion around the apex of a stable implant diagnosed radiographically as a radioluscency in the bone at the apical part of an implant.The IPL can perform with or without clinical symptoms such as tenderness, swelling, suppuration and fistulation. This report describes 4 cases of IPL which were treated surgically

Kraven på mera avancerade verifieringsmetoder har ökat i takt med att det traditionella sättet att projektera en byggnads brandskydd har förändrats, samt att vi idag är mer medvetna om vilka riskerna är, t ex att tillförlitlighet i tekniska skyddssystem måste beaktas. Detta är nödvändigt för att säkerställa att samhällets krav på brandsäkerhet efterlevs och uppfylls.

Kallikrein 1 (KLK1), a key component of the kallikrein-kinin system, originates from a locus on the long arm of chromosome 19 that contains several related serine endopeptidases. The biological role of these kallikrein-related peptidases is not clear, but emerging evidence suggests that they might be important in several physiological systems, e.g., in male reproduction, skin homeostasis, tooth en

BACKGROUND: Limb development and patterning originate from a complex interplay between the skeletal elements, tendons, and muscles of the limb. One of the genes involved in patterning of limb muscles is the homeobox transcription factor Pitx2 but its role in forelimb development is uncharacterized. Pitx2 is expressed in the majority of premature presumptive forelimb musculature at embryonic day 12

The ability to understand and communicate about the actions of others is a fundamental aspect of our daily activity. How can we talk about what others are doing? What qualities do different actions have such that they cause us to see them as being different or similar? What is the connection between what we see and the development of concepts and words or expressions for the things that we see? To

Our purpose was to examine self-efficacy of knee function, physical activity (PA) and health-related quality of life (HRQoL) in post-meniscectomy patients and controls as well as to explore the impact of gender and the association between outcomes. Ninety-nine post-meniscectomy patients (27% women), mean age 44.5 years, mean (range) of follow-up time 3 (1-5) years, and 94 controls (34% women), mea

In recent years, a number of new developments in targeted therapies using radiolabeled compounds have emerged. New developments and insights in radioiodine treatment of thyroid cancer, treatment of lymphoma and solid tumors with radiolabeled monoclonal antibodies (mAbs), the developments in the application of radiolabeled small receptor-specific molecules such as meta-iodobenzylguanidine and pepti

PURPOSE: To study long term loco-regional and distant recurrence rate and survival after post-mastectomy radiotherapy in combination with oral cyclophosphamide in premenopausal women with stage II breast cancer. STUDY DESIGN: A three-armed randomized multicenter phase III trial comparing 1) Radiotherapy (RT) 2) RT+ oral cyclophosphamide for one year (RT+C) and 3) Oral cyclophosphamide only (C). Ra