Direct electrochemical measurements of glutamate release in vivo were combined with optogenetics in order to examine light-induced control of glutamate neurotransmission in the rodent brain. Self-referenced recordings of glutamate using ceramic-based microelectrode arrays (MEAs) in hippocampus and frontal cortex demonstrated precise optical control of light-induced glutamate release through channe

Low-molecular-weight heparin (LMWH) is often recommended as a bridging therapy during temporary interruptions in warfarin treatment, despite lack of evidence. The aim of this study was to see whether we could find benefit from LMWH bridging. We studied all planned interruptions of warfarin within the Swedish anticoagulation register Auricula during 2006 to 2011. Low-molecular-weight heparin bridgi

Det är lätt att bli nyfiken om man promenerar längs gatan i ett villaområde med rader av trädgårdar där olika projekt, stilar, material och växter avlöser varandra. Här lever människor med skilda erfarenheter, drömmar och ideal. De skapar sina egna miniatyrvärldar men delar samtidigt ljud, dofter, synintryck och gränser. Ett eget utomhus men på många sätt ett gemensamt utomhus. I den här boken utf

This is Part 1 of an article arguing for an extended application of Karl Marx’s insight that the apparent reciprocity of free market exchange is to be understood as an ideology that obscures material processes of exploitation and accumulation. Rather than to confine this insight to the worker’s sale of his or her labor-power for wages, and basing it on the conviction that labor-power is uniquely c

This is Part 2 of an article arguing for an extended application of Karl Marx’s insight that the apparent reciprocity of free market exchange is to be understood as an ideology that obscures material processes of exploitation and accumulation. Rather than confine this insight to the worker’s sale of his or her labor-power for wages, and ground it in the conviction that labor-power is uniquely capa

The holotype (MHM-K2) of the Eocene cheloniine Tasbacka danica is arguably one of the best preserved juvenile fossil sea turtles on record. Notwithstanding compactional flattening, the specimen is virtually intact, comprising a fully articulated skeleton exposed in dorsal view. MHM-K2 also preserves, with great fidelity, soft tissue traces visible as a sharply delineated carbon film around the bon

There has been much interest recently in the relationship between economic conditions and mortality, with some studies showing that mortality is pro-cyclical, while others find the opposite. Some suggest that the aggregation level of analysis (e.g. individual vs. regional) matters. We use both individual and aggregated data on a sample of 20–64 year-old Swedish men from 1993 to 2007. Our results s

Situated in a broader anthropocentric and speciesist structure, carnism serves to perpetuate the objectification and exploitation of other animals. In this paper, carnistic thinking is examined in the context of how it is commonly applied to dogs, who are framed as lovable, yet subordinate to humans. Through critically discussing the social system of domestication, and by relating carnistic ideolo

Gene sequences form the primary basis for understanding the relationships among extant plant groups, but genetic data are unavailable from fossils to evaluate the affinities of extinct taxa. Here we show that geothermally resistant fossil cuticles of seed-bearing plants, analysed with Fourier transform infrared (FTIR) spectroscopy and hierarchical cluster analysis (HCA), retain biomolecular suites

Engineering asset management (EAM) is an emergent field where research has followed various lines of interest. To better understand these lines of interest, a conceptual framework is developed to depict the scope of the EAM research arena, provide an overview of the current 'state of play' in EAM research and assist in identifying areas where further research could be directed. The relative lack o

When major retailers move into the healthcare market and establish new types of retailing format, such as retail clinics, healthcare is no longer far from the retailing arena. Meanwhile, the rhetoric shift from patients to healthcare consumers signals a change of strategy within publicly-funded healthcare and demands it to think about how their service should be packaged and delivered. It therefor

Introduction: We investigate the risks of subsequent primary bone cancers after childhood and adolescent cancer in 12 European countries. For the first time, we satisfactorily address the risks beyond 40 years from diagnosis and beyond 40 years of age among all survivors.Methods: This largest-ever assembled cohort comprises 69 460 five-year survivors of cancer diagnosed before age 20 years. Standa

When new buildings are constructed the indoor climate for the first period may differ from the one after some years due to various factors, for example may the emissions from the building materials be higher, possibly affecting the air quality, and the balancing of the technical systems; the mechanical supply and exhaust system and heating may not be completely finished. The perceived indoor clima

Along with the increasing incidence and favorable prognosis, more women diagnosed with endometrial cancer may develop second primary cancers (SPCs). We aimed at investigating risk of SPCs after endometrial cancer in Germany and Sweden to provide insight into prevention strategies for SPCs. Endometrial cancer patients diagnosed at age ≥15 years in Germany during 1997–2011 and in Sweden nationwide d

Aims This prospective study focuses on risk factors for arterial damage in children with type 1 diabetes (T1D). Methods Eighty children and adolescents with T1D were investigated twice, approximately 2 years apart, for carotid artery intima-media thickness (cIMT) and compliance (CAC), flow-mediated dilatation (FMD) of the brachial artery, and plasma levels of matrix metalloproteinase (MMP)-8. Al

The apartment-block of Flagghusen in Malmö in the south of Sweden was built and designed with the intention to achieve a lower energy use compare to the regulations and a good indoor environment. The outcome of this ambition was evaluated in a first report in 2010 that showed that the overall notion of the perceived indoor climate in the apartments were good but that the measured energy use exceed

Objective. To compare the rate of severe infections after the onset of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with the rate in the background population, and to identify predictors of severe infections among patients with AAV. Methods. The study cohort was 186 patients with AAV diagnosed from 1998 to 2010, consisting of all known cases in a defined population in sou

Introduction Childhood allergic diseases may prevent affected children from achieving their academic potential. Potential mechanisms include absence from school due to illness and medical appointments. Experience of symptoms in classes or leisure time, and stigma associated with visible signs and symptoms, including skin disease, requirements for medication during school time or the need for speci