Background: There is almost no data on the combined associations between apolipoprotein E gene (APOE) genotypes, trace elements (TEs), and lipid peroxidation in vivo. The aim of our study was to evaluate the association between APOE genotypes and TE levels in blood (B-TEs) and erythrocytes (E-TEs), and 8-isoprostane in urine (U-8-isoprostane) in women with low exposure to potentially toxic TEs and

Purpose: The survival rate of breast cancer for women in low- and middle-income countries is poor compared with that in high-income countries. Point-of-care ultrasound (POCUS) combined with deep learning could potentially be a suitable solution enabling early detection of breast cancer. We aim to improve a classification network dedicated to classifying POCUS images by comparing different techniqu

BackgroundCritical COVID-19 is associated with high mortality, and acute kidney injury (AKI) is common. Endostatin has emerged as a promising prognostic biomarker for predicting AKI and mortality in intensive care. This study aimed to investigate plasma endostatin at intensive care unit (ICU) admission as a biomarker for AKI, renal replacement therapy (RRT), and 90-day mortality in COVID-19.Method

Background: End-of-life care in the Intensive Care Unit (ICU) is complex, requiring a balance of ethical, cultural and medical considerations while ensuring comfort and dignity for critically ill patients and their families.Aim: We aimed to develop a set of core domains for end-of-life care at Scandinavian ICUs along with corresponding consensus statements from patients, families and multidiscipli

Introduction: As the Chinese immigrant population in European countries ages, it is important to gain a deeper understanding of Chinese immigrants’ ageing processes from a life course perspective by recognising the complex interactions between social, cultural, and institutional constructs and dynamics. This article aimed at exploring how older Chinese immigrants in Europe handle everyday lives in

This single case study illuminates the complexity of successful classroom management. Framing classroom management as ritualized community building (Bell, 2009), we show how a teacher’s interaction rituals (Collins, 2004), emotional labor (Scheff, 1994), and professional improvisation (Sorensen, 2023) are integrated in this process. Based on observations of a primary schoolteacher’s classroom mana

Background: Guidelines recommend neoadjuvant chemotherapy (NAC) and radical cystectomy (RC) for muscle-invasive bladder cancer (MIBC). Current recommendations do not consider genomic profiles, although the Basal/Squamous (Ba/Sq) subtype is less likely to respond to NAC compared to Urothelial-like (Uro) and Genomically Unstable (GU) subtypes. The aim of this study is to perform cost-effectiveness a

However, it is not clear to what extent corresponding perceptual preferences for intonational deviations might rely on listeners’ instrumental expertise or such contextual aspects as the metrical placement of tones. We investigated higher-education music students’ perceptual preferences for melodic intonation of local leading tones in unaccompanied classical violin performances. Recordings of 12 e

We present a theory of the inner layer of the cerebellar cortex, the granular layer, where the main excitatory input to the cerebellum is received. We ask how input signals are converted into an internal code and what form that has. While there is a computational element, and the ideas are quantified with a computer simulation, the approach is primarily evidence-led and aimed at experimenters rath

New political parties are founded all the time. Most of them never reach a significant share of the vote and eventually give up. So why did the newly founded ‘Democratic Alliance for Diversity and Awakening’ (Demokratische Allianz für Vielfalt und Aufbruch, DAVA) provoke a backlash in Germany? Various government heavyweights as well as opposition politicians reacted with disapproving statements –

Challenges of intonation derive from discrepancies between justly tuned intervals. In theoretical literature, string intonation is depicted as a balancing act between melodic and harmonic ideals, or between distinct tuning systems. However, practical string teachers’ and empirical researchers’ accounts sometimes appear to bypass such theory, focusing instead more informally on listening, kinesthet

Hospitals were among the wealthiest organizations in medieval cities. Their directors managed portfolios consisting of real estate and financial instruments; as a result, they also handled large quantities of money. It has been suggested that they used these to provide a variety of financial services and performed early banking functions. In this study I focus on the role hospitals played in allow

String intonation is a topic of pedagogical interest, but also a domain involving implicit, embodied knowledge that may be hard to convey in words. This study investigated how prominent string musicians approach expressive aspects of intonation, when only verbal means of pedagogical communication are possible. A search through the professional periodical The Strad with the combined keywords “expre

The last several years of research, including children followed from birth and extensive genetic studies, have resulted in a paradigm shift of the etiology and pathogenesis of type 1 diabetes mellitus (T1DM). Autoimmune T1DM is characterized by the appearance in early childhood of a first β-cell autoantibody against either insulin (IAA) or GAD65 (GADA), or both. The genetic etiology is strongly as

Innovation plays a crucial role in shaping technological, economic, and social progress in modern societies. In the realm of bridge integrity management, the development and diffusion of technologies to acquire information can significantly enhance industries' safety and functionality capabilities. Among the most widely diffused bridge types in Europe and North America, Gerber bridges are particul

In this review, we analyze the existing literature on the role of alternative currencies within degrowth. While degrowth emerged in the early 2000s alongside growing awareness of accelerating environmental crises and widening global inequalities, alternative currencies have a longer history. Alternative currencies have served as devices for communities seeking to become less dependent on the domin