The aim of this thesis has been to provide further understanding of skin barrier function from a chemical point of view. The main barrier is known to be located in the outermost layer of the skin, stratum corneum, composed of cornified flattened cells in conjunction with an extracellular lipid-water matrix. From literature it is evident that the lipids of this matrix are arranged as bilayers, alig

The memo is a short summary of the impressions that have come out of the LUSAX research to date from an alliance perspective. The main focus is on the lack of clear vision of intended goal or target within the industry. The end conclusion being that companies that wish to succeed need to formalize a strategy with a clear goal and a positioning towards that goal, with explicit intent and coordinati

This work explores the linguistic encoding of reciprocal events in Jahai (Aslian, Mon-Khmer, Malay Peninsula) on the basis of linguistic descriptions of the video stimuli of the 'Reciprocal constructions and situation type' task (Evans et al. 2004). Reciprocal situation types find expression in three different constructions: distributive verb forms, reciprocal verb forms, and adjunct phrases conta

The concept “Broken Technologies” is related to the question: “Which is the benefit of humanity studies?” Of course the question is rhetorical because, how could this question be answered if the benefit was not obvious? Any answer supposes that we understand what we are asking for and the study of “what we mean” is one of the axes of the epistemology of the humanities. Anyway, we can also put the

Popular Abstract in Swedish En av de viktigaste frågeställningarna inom molekylär genetik är hur uttrycket av människans ca 30-40 000 gener regleras i tid och rum. En typ av reglering som är väldigt viktig är transkriptionell reglering och denna utövas av proteiner som kallas transkriptionsfaktorer. Dessa binder till specifika områden i DNA strängarna i närheten av genkodande regioner och kan däriNeuroblastoma is a childhood tumor derived from primordial neural crest cells. The tumor cells exhibit a phenotype similar to that of developing neuroblasts, which indicates that the tumor arises due to perturbed differentiation of the sympathetic nervous system. It is well established that transcription factors control the steps leading to neuronal differentiation, and a number of basic helix-loo

Popular Abstract in Swedish Järn har den kemiska beteckningen Fe från latinskans ferrum. Det är det fjärde vanligaste ämnet i världen och utgör ca en femtedel av jordskorpan. Trots det kan både djur och växter ha järnbrist. Hur kan detta vara möjligt? Problemet är egentligen inte förekomsten av järn utan att järnet som vi och alla andra organismer behöver har oxidationstillståndet Fe(II) medan detIt is of vital importance to understand the systems for iron metabolism and this thesis contributes to this by providing insights into the structure and function of the acquisition and homeostasis of iron. The two proteins that have been primarily investigated are a ferric reductase from Arabidopsis thaliana called FRO2 and a mitochondrial iron chaperone from Saccharomyces cerevisiae called fratax

Det här kapitlet tar upp hur vardagslivet kan te sig för personer som har ett psykiskt funktionshinder. Vardagen består för oss människor av olika sysslor, och vi upplever dem på olika sätt och de betyder olika saker. Många av dem utförs automatiskt utan reflektion, som exempelvis att duscha på morgonen eller att handla på hemvägen från jobbet. Det kan sägas vara en slags autopilot inkopplad som g

A theoretical review of the concept of vendor managed inventory is presented. The objective with the study is two fold. First of all the study tries to sort out the different terms connected with VMI and secondly former research about the VMI concept is presented.

Large-scale distributed networks are not easy to control centrally. Local set-point variations will likely create flooding alarm fluctuations. However, local control can cause emergence of unwanted network behavior. The paper overviews the problems with model-based control in sensory networks, such as currently rolled out for the Electric Grid, and shows how networked intelligence can bridge betwe