Popular Abstract in Swedish Proteiner är livsnödvändiga och finns i alla celler. De flesta proteinerna katalysear kemiska reaktioner och kallas då enzymer. Enzymer och proteiner (äggviteämnen) är uppbyggda av aminosyror ihopkopplade till kedjor som kan vara olika långa. Det finns 20 stycken olika aminosyror. Man kan göra en liknelse med ett pärlhalsband tillverkat av 20 olika pärlor, varje pärla mFerrochelatase catalyses the terminal step in heme biosynthesis by inserting a ferrous ion into protoporphyrin IX. The reaction mechanism has in this thesis been studied by mainly crystallographic methods. The structure of ferrochelatase from Bacillus subtilis co-crystallized with N-methyl mesoporphyrin allowed for the first time a characterization of the active site of the enzyme. The structure

Financial theory, resource-based theory and deal flow generation are used to explain synd ication practices among venture capitalists in Belgium, France, The Netherlands, Sweden and the UK. Similar motives drive syndication in the five countries: the desire to share risk and increase portfolio diversification is more important than the desire to access additional intangible resources or deal flow.

Three methods are presented to calculate the load distribution in a chain drive containing two sprockets and one chain. The rollers, which are in contact with the sprockets, can move along the tooth flanks and their positions are given by force equilibrium. Since the positions of the rollers, and thereby also the load distribution, depend on the two connecting spans, it has been necessary to inclu

A systematic study of cell membrane morphologies whose structure is governed by cubic symmetries has been performed. It is suggested that they are described by periodic cubic surfaces for which space filling surface foliations given by truncated Fourier series defined by the space groups is used as structural representations. Using this a method is developed which enables a direct ultrastructural

This paper examines how social relations and norms contribute to the emergence of generalized trust in economic action. Our core proposition is that the more positive the local social exchange relationship, the greater an actor’s propensity to place trust in strangers. Our research design integrates behavioral measures elicited by incentivized experimental trust games with survey data using a rand

The Gas in scattering media absorption spectroscopy (GASMAS) technique provides new opportunities to nondestructively study gas in highly scattering natural and man-made porous materials. In this paper, we report applications of the GASMAS method on wood samples using diode-laser-based spectroscopy on molecular oxygen. And the integrated oxygen absorption for wood of different densities and the an

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Ökar världens befolkning snabbare än tillgången på mat? Är lösningen på världens livsmedelsproblem att omfördela maten mellan fattiga och rika länder? Göran Djurfeldt svarar nej på båda frågorna. Mera mat handlar om produktionen snarare än om fördelningen av livsmedel: världens jordbruk måste bli effektivare för att kunna mätta en växande befolkning. Boken analyserar jordbruket i ett globalt pers

Atherosclerosis as a disease is postulated to stem from a response to injury of the arterial wall by various stimuli. The inflammatory response is proposed to mediate intimal formation after injury. One pathway of cellular response to injury is through transcription factor NF-kB. We show that balloon injury of rat arteries leads to increased NF-kB activity and ICAM-1 expression, associated with i

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