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Effects of long-term exposure to air pollution on natural-cause mortality : An analysis of 22 European cohorts within the multicentre ESCAPE project

Background Few studies on long-term exposure to air pollution and mortality have been reported from Europe. Within the multicentre European Study of Cohorts for Air Pollution Effects (ESCAPE), we aimed to investigate the association between natural-cause mortality and long-term exposure to several air pollutants. Methods We used data from 22 European cohort studies, which created a total study pop

Characterization of antioxidant polyphenols from Myrciaria jaboticaba peel and their effects on glucose metabolism and antioxidant status : A pilot clinical study

Brazilian berries, such as Myrciaria jaboticaba (jaboticaba), are good sources of polyphenols with a recognized function in oxidative stress attenuation proved in non-clinical studies. In the present study, the polyphenols profile and their contribution to the antioxidant capacity of the jaboticaba peel were analyzed using high-performance liquid chromatography (HPLC) with photodiode array (DAD),

Determination of free and esterified carotenoid composition in rose hip fruit by HPLC-DAD-APCI+-MS

Rose hip fruit, which contains high concentration of carotenoids is commonly used for different food products in Europe and it is considered to have medical properties. In this study, a simple, rapid and efficient HPLC-DAD-APCI+-MS method was developed and applied to identify and quantify the carotenoids in rose hip fruit of four rose species, including both unsaponified and saponified extract. In

Accelerated creep in solid oxide fuel cell anode supports during reduction

To evaluate the reliability of solid oxide fuel cell (SOFC) stacks during operation, the stress field in the stack must be known. During operation the stress field will depend on time as creep processes relax stresses. The creep of reduced Ni-YSZ anode support at operating conditions has been studied previously. In this work a newly discovered creep phenomenon taking place during the reduction is

Manganese concentrations in drinking water from villages near banana plantations with aerial mancozeb spraying in Costa Rica : Results from the Infants' Environmental Health Study (ISA)

Elevated manganese (Mn) in drinking water has been reported worldwide. While, naturally occurring Mn in groundwater is generally the major source, anthropogenic contamination by Mn-containing fungicides such as mancozeb may also occur. The main objective of this study was to examine factors associated with Mn and ethylenethiourea (ETU), a degradation product of mancozeb, in drinking water samples

Arterial blood pressure and long-term exposure to traffic-related air pollution : An analysis in the european study of cohorts for air pollution effects (ESCAPE)

Background: Long-term exposure to air pollution has been hypothesized to elevate arterial blood pressure (BP). The existing evidence is scarce and country specific. Objectives: We investigated the cross-sectional association of long-term traffic-related air pollution with BP and prevalent hypertension in European populations. Methods: We analyzed 15 population-based cohorts, participating in the E

Air pollution and nonmalignant respiratory mortality in 16 cohorts within the ESCAPE project

Rationale: Prospective cohort studies have shown that chronic exposure to particulate matter and traffic-related air pollution is associated with reduced survival. However, the effects on nonmalignant respiratory mortality are less studied, and the data reported are less consistent. Objectives: We have investigated the relationship of long-term exposure to air pollution and nonmalignant respirator

Making Place for Social Norms in the Design of Human-Robot Interaction

We argue that social robots should be designed to behave similarly to humans, and furthermore that social norms constitute the core of human interaction. Whether robots can be designed to behave in human-like ways turns on whether they can be designed to organize and coordinate their behavior with others’ social expectations. We suggest that social norms regulate interaction in real time, whereage

Membrane interactions of mesoporous silica nanoparticles as carriers of antimicrobial peptides

Membrane interactions are critical for the successful use of mesoporous silica nanoparticles as delivery systems for antimicrobial peptides (AMPs). In order to elucidate these, we here investigate effects of nanoparticle charge and porosity on AMP loading and release, as well as consequences of this for membrane interactions and antimicrobial effects. Anionic mesoporous silica particles were found

Immunohistochemical localization of the calcitonin gene-related peptide binding site in the primate trigeminovascular system using functional antagonist antibodies

Calcitonin gene-related peptide (CGRP) is a potent vasodilator and a neuromodulator implicated in the pathophysiology of migraine. It binds to the extracellular domains of calcitonin receptor-like receptor (CLR) and receptor activity-modifying protein (RAMP) 1 that together form the CGRP receptor. Antagonist antibodies against CGRP and its binding site at the receptor are clinically effective in p

Upper Ordovician δ13Corg chemostratigraphy, K-bentonite stratigraphy, and biostratigraphy in southern Scandinavia : A reappraisal

A pioneer δ13Corg study through the upper Sandbian and Katian (Upper Ordovician) succession in the Röstånga 1 drill core in the classical geological outcrop area at Röstånga in southernmost Sweden produced a wealth of new carbon isotope data which are useful for local and regional correlations. Among the Upper Ordovician positive δ13C excursions, the Guttenberg (GICE), Waynesville (Saunja), Whitew

Hydrogenation induced structure and property changes in GdGa

Hydrides GdGaHx were obtained by exposing the Zintl phase GdGa with the CrB structure to a hydrogen atmosphere at pressures from 1.5 to 50 bar and temperatures from 50 to 500 °C. Structural analysis by powder X-ray diffraction suggests that conditions with hydrogen pressures in a range between 15 and 50 bar and temperatures below 500 °C afford a uniform hydride phase with the NdGaH1.66 structure (