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Purpose This paper investigates how the balanced scorecard (BSC) has been translated to fit the public healthcare environment. The paper discusses how the context, consisting of politicians, administrators, and medical professionals has influenced the design and function of the BSC. Design/methodology/approach A qualitative case study approach involving semi-structured interviews were conducted wi
The uniform organisation of the neuronal circuitry throughout the cerebellar cortex suggests a uniform mode of operation and thus emphasises the importance of local afferent and efferent connections in determining the function of a particular part of the cortex. Based on the organisation of these connections the cerebellar cortex of the cat is divided into about ten sagittally oriented zones (see
Background: The COVID-19 pandemic presents great challenges on transmission prevention, and rapid diagnosis is essential to reduce the disease spread. Various diagnostic methods are available to identify an ongoing infection by nasopharyngeal (NPH) swab sampling. However, the procedure requires handling by health care professionals, and therefore limits the application in household and community s
Distributed e-Infrastructure is a key component of modern BIG Science. Service discovery in e-Science environments, such as Worldwide LHC Computing Grid (WLCG), is a crucial functionality that relies on service registry. In this paper we re-formulate the requirements for the service endpoint registry based on our more than 10 years experience with many systems designed or used within the WLCG e-In
One of the points on which researchers agree is the centrality of autonomy to professionalism. Moreover, a common conclusion in the studies of professions is that the profound changes in society over the last fifty years have threatened the autonomy and changed the archetype of professionalism. This paper contributes to the research on changes and continuities, challenges and opportunities for pro
There is an increasing interest in acoustics for microfluidic applications. This field, commonly known as acoustofluidics involves the interaction of ultrasonic standing waves with fluids and dispersed microparticles. The combination of microfluidics and the so-called acoustic standing waves (ASWs) led to the development of integrated systems for contact-less on-chip cell and particle manipulation
Background: Acute Compartment syndrome (ACS) with subsequent need for fasciotomy is a serious and insidious complication after revascularization for acute lower limb ischemia (ALI). The development of ACS during endovascular catheter directed thrombolysis is particularly difficult to identify. The aim was to identify the incidence, predisposing factors, wound treatment, and outcome in terms of amp
Background: Opioid-based treatment is used to manage stress responses during surgery and postoperative pain. However, opioids have both acute and long-term side effects, calling for opioid-free anaesthetic strategies. This meta-analysis compares adverse events, postoperative recovery, discharge time from post-anaesthesia care unit, and postoperative pain, nausea, vomiting, and opioid consumption b
During severe inflammatory and infectious diseases, various mediators modulate the equilibrium of vascular tone, inflammation, coagulation and thrombosis. This Review describes the interactive roles of the renin–angiotensin system, the complement system, and the closely linked kallikrein–kinin and contact systems in cell biological functions such as vascular tone and leakage, inflammation, chemota
Introduction: Recurrent bleeding in severe haemophilia B causes painful hemarthroses and reduces capacity for physical activity. Recombinant factor IX Fc fusion protein (rFIXFc) prophylaxis results in low annualised bleeding rates, with the potential to improve patients’ health-related quality of life (HRQoL). Aim: To present a post hoc analysis of data from B-LONG describing change over time in p
In this paper, I evaluate some recent attacks on Williamson's claim that knowledge is the most general factive stative propositional attitude. Two types of approaches are discussed: The first approach attempts to show that there are factive mental states denoted by factive mental state operators that are not cases of knowing. The second approach aims to show that there are factive mental states th
Pharmacological and genetic evidence support a role for an involvement of the dopamine D2-receptor (D2-R) in the pathophysiology of schizophrenia. Previous molecular imaging studies have suggested lower levels of D2-R in thalamus, but results are inconclusive. The objective of the present study was to use improved methodology to compare D2-R density in whole thalamus and thalamic subregions betwee
Sexual and reproductive health and rights (SRHR) are an essential component of universal health coverage (UHC). In determining which SRHR interventions to include in their UHC benefits package, countries are advised to evaluate each service based on robust and reliable data, including cost-effectiveness data. We conducted a scoping review of full economic evaluations of the essential SRHR interven
Lateral III-V nanowire (NW) MOSFETs are a promising candidate for high-frequency electronics. However, their circuit performance is not yet assessed. Here, we integrate lateral nanowires (LNWs) in a circuit environment and characterize the transistors and amplifiers. MOSFETs are fabricated in a simple scheme with a dc transconductance of up to 1.3 mS/μm, ON-resistance down to 265 &#
This article contributes to ongoing discussions about frailty and vulnerability in critical gerontology by asserting that possibilities to engage and enact influence in everyday life situations is a crucial dimension of democracy in later life. We discuss how democracy in this sense can be threatened for older persons for whom health and social care services are needed, following from the labellin
Purpose: To analyze the relationship between rates of false positive (FP) responses and standard automated perimetry results. Design: Prospective multicenter cross-sectional study. Methods: One hundred twenty-six patients with manifest or suspect glaucoma were tested with Swedish Interactive Thresholding Algorithm (SITA) Standard, SITA Fast, and SITA Faster at each of 2 visits. We calculated inter
In this preliminary report we present data showing that leukotrienes increase the baseline cell viability in human intestinal epithelial cells and that LTB4 partially reverses the morphological hallmarks of non-necrotic cell death induced by the COX-2 specific inhibitor NS-398. The proposed signaling mechanisms regulating these events are summarized in fig. 3. Please view the work on LT signal tra
The analysis of DNA methylation has become an established method for chronological age estimation. This has triggered interest in the forensic community to develop new methods for age estimation from biological crime scene material. Various assays are available for age estimation from somatic tissues, the majority from blood. Age prediction from semen requires different DNA methylation markers and
Background: Resting metabolic rate (RMR) has been examined as a proxy for low energy availability (EA). Previous studies have been limited to adult athletes, despite the serious health consequences of low EA, particularly during adolescence. This study aimed to explore the relationship between RMR and EA in competitive teenage girl runners. Methods: Eighteen girl runners (mean ± standard-deviation
