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The molecular chaperone DNAJB6 has conserved serine (S) and threonine (T) residues, which are crucial for its ability to efficiently suppress amyloid formation of aggregation-prone amyloidogenic peptides. Substitution of the conserved ST-residues with alanine residues results in loss of this function. These functionally important conserved ST-residues are located in a C-terminal domain, which is c
