Elucidating the genetic and molecular basis of SWI/SNF-driven divergent non-coding transcription
The discovery of pervasive transcription in eukaryotic organisms reveals that majority of promoters produce divergent non-coding transcripts besides their annotated transcripts. A recent study proposed the activation of divergent transcription by SWI/SNF chromatin remodelers. Mutating SNF5 subunit of the complex resulted in decreased levels of divergent transcription. Based on this finding, genomi
