OBJECTIVE: In 17 patients with chronic sinusitis persistent after sinus surgery, long-term, low-dose erythromycin therapy was tested. The aim of the investigation was to study the clinical outcome and effects on nasal nitric oxide (NO), ciliary beat frequency (CBF), and mucociliary transport (saccharine transit time). STUDY DESIGN AND SETTING: We conducted a prospective open study at a tertiary te

We used a mass spectrometry-based assay for identifying the endotoxin (lipopolysaccharide, LPS) marker (R)-3-hydroxytetradecanoic acid in cigarette smoke particles and found that smoking involved inhalation of 17.4 pmol of endotoxin per each smoked cigarette. Indoor exposure to environmental tobacco smoke (ETS) entailed inhalation of 12.1 pmol of LPS/m3 air, an amount that was 120 times higher tha

The epitaxial system Sm/Co(0001) was studied for Sm coverages up to 1 monolayer (ML) on top of ultrathin Co/W(110) epitaxial films. Two ordered phases were found for 1/3 and 1 ML Sm, respectively. The valence state of Sm was determined by means of photoemission and magnetic properties were measured by magneto-optical Kerr effect. We find that 1 ML Sm causes a strong increase of the coercivity with

Studies of haematological neoplasms have shown that alterations in structure and/or expression of transcription factor genes may play a crucial role for transforming stem cells or progenitor cells into malignant cells. These mutations typically arise through balanced translocations and appear to induce a block in cellular differentiation. The impact of the transforming mutation is highly dependent

PURPOSE. Integration between subretinal grafts and the host retina is limited in part by the presence of a barrier at the graft-host interface. This study was conducted to identify factors that may contribute to this barrier, by examining the distribution of glial structures and associated molecules in different setups of overlapping retinal pieces. METHODS. Neuroretinal tissue derived from mice t

The dystrophin-glycoprotein complex (DGC) is a multisubunit complex that connects the cytoskeleton of a muscle fiber to its surrounding extracellular matrix. Mutations in the DGC disrupt the complex and lead to muscular dystrophy. There are a few naturally occurring animal models of DGC-associated muscular dystrophy (e.g. the dystrophin-deficient mdx mouse, dystrophic golden retriever dog, HFMD ca

Syftena med det i projektet beskrivna inlärnings- experimentet var att studera barns attityder till våld och att med ett attitydtest undersöka effekterna av undervisning mot våld. Samtidigt jämfördes individuellt arbete och grupparbete samt användningen av tre slag av läromedel: texter, bilder och muntliga uppgifter. Både process- och produktvariabler undersöktes. Deltagare var elever i åldrarna 1The main aim of this study has been to influence the attitudes of students, Grades 4-6, in order that they will become opposed to the use of violence. The entire project was conducted during a full academic 20-credit term, as part of inter- mediate level teachers' training. The purpose of this learning experiment was threefold: 1. To study children's attitudes towards violence. 2. To study the eff

Genetic segregation analysis between NOD and C57BL strains have been used to identify loci associated with autoimmune disease. Only two loci (Cia2 and Cia9) had earlier been found to control development of arthritis, whereas none of the previously identified diabetes loci was of significance for arthritis. We have now made a high-powered analysis of a backcross of NOD genes on to the B10.Q strain

The aim of this study was to evaluate the global sequence of repolarization over the ventricular endocardium. Disturbances in myocardial repolarization are associated with the genesis of arrhythmias. However, little is known about the global sequence of repolarization. Monophasic action potentials (MAPs) were recorded from 61 +/- 18 LV and/or RV sites in ten healthy pigs and from 43 +/- 15 LV or R

In an investigation by the Swedish Cancer Society, an expert group described the present status, critical issues and future aspects and potentials for each of nine major areas of radiation therapy research. The present report deals with the use of sensitizing and protective substances in radiation therapy and predictive assays on normal tissues and tumour response.

We report the results of an intercomparison of vertical column amounts of HCl, HF, N(2)O, HNO(3), CH(4), O(3), CO(2) and N(2) derived from the spectra recorded by two ground-based FTIR spectrometers operated side-by-side using the sun as a source. The procedures used to record spectra and derive vertical column amounts followed the format of previous instrument intercomparisons organised by the Ne

This thesis deals with the task of modeling a web server and designing a mechanism that can prevent the web server from being overloaded. Four papers are presented. The first paper gives an M/G/1/K processor sharing model of a single web server. The model is validated against measurements ands imulations on the commonly usedw eb server Apache. A description is given on how to calculate the necessar

This report deals with stability and validity analyses of direct tension tests, and an investigation into structural behaviour of various materials in tensile fracture. The influence of rotation in damage zone on the stress-deformation curve is investigated. The role of rotation stiffness of testing set-ups for a stable tension test is analysed. The bump effect, i.e. steep stress drops in stress-d