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PURPOSE: To present a new perimetric index for calculating the rate of glaucomatous progression and to compare its performance with the traditional mean deviation index (MDI). DESIGN: Experimental study describing a device and retrospective cohort study. METHODS: We developed a new visual field index, the glaucoma progression index (GPI), intended to be less affected by cataract than the MDI by ca
Life is polymeric in its essence. The living cell contains a range of biopolymers such as proteins, carbohydrates, and nucleic acids. The cells are often compartmentalized via membranes that are composed of lipids. These are small molecules, but they spontaneously aggregate into supermolecular structures. The building blocks of these lipids are among others fatty acids, structures built from methy
Question: Under what circumstances are local communities and metacommunities phylogenetically clustered, overdispersed or random assemblages in terms of phylogenetic relatedness? Methods: An individual-based eco-evolutionary model was used to explain the link between system properties, ecological and evolutionary processes, and phylogenetic patterns in a spatially explicit competitive metacommunit
Previous research on human fear of large carnivores has mainly been based on self-reports in which individual survey items and the objects of fear are measured, so whether a person fears attacks on humans or livestock and pets has not been identified. The objectives of this study were to differentiate between the objects of fear as well as capturing attitudes towards implementation of management a
Single-crystal neutron diffraction reveals two distinct components to the magnetic ordering in geometrically frustrated SrEr2O4. One component is a long-range ordered k = 0 structure which appears below T-N = 0.75 K. Another component is a short-range incommensurate structure which manifests itself by the presence of a strong diffuse scattering signal. On cooling from higher temperatures down to 0
Excessive complement activation contributes to joint diseases such as rheumatoid arthritis and osteoarthritis during which cartilage proteins are fragmented and released into the synovial fluid. Some of these proteins and fragments activate complement, which may sustain inflammation. The G3 domain of large cartilage proteoglycan aggrecan interacts with other extracellular matrix proteins, fibulins
We study the zero sets of random analytic functions generated by a sum of the cardinal sine functions which form an orthonormal basis for the Paley-Wiener space. As a model case, we consider real-valued Gaussian coefficients. It is shown that the asymptotic probability that there is no zero in a bounded interval decays exponentially as a function of the length. (C) 2012 Elsevier Inc. All rights re
Background: Type 2 diabetes has been associated with increased incidence of atrial fibrillation (AF) and cardiovascular disease. Controversy remains regarding the role of insulin in the epidemiology of AF risk. The aim of the present study was to study the association between fasting plasma insulin (FPI) and incidence of AF, as well as any effect modification by fasting blood glucose (FBG) or 2 h
An array of simulated intestinal fed-state fluids, where phosphatidylcholine (PC) was replaced by lysophosphatidylcholine (LPC) and cholesterol (Chol) was added, were visualized with Cryogenic Transmission Electron Microscopy (Cryo-TEM). Micelles were the dominating structural features, emphasizing the micellar-forming characteristics of LPC. Upon increase of the monoglyceride (MG) level, unilamel
Retrospective water quality assessment plays an essential role in identifying trends and causal associations between exposures and risks, thus it can be a guide for water resources management. We have developed empirical relationships between several time-varying social and economic factors of economic development, water quality variables such as nitrate-nitrogen, COD(Mn), BOD(5), and DO, in the J
In this paper, I argue that there is a paradigm shift in George Berkeley's philosophy between his early unpublished manuscripts (1707-1708) and the Theory of Vision (1709). If so, the traditional method of mixing published and unpublished material will lead to a confused picture of both his early, unpublished view and the doctrine that lie published.
The gp130 receptor and its binding partners play a central role in cytokine signalling. Ciliary neurotrophic factor (CNTF) is one of the cytokines that signals through the gp130 receptor complex. CNTF has previously been shown to be a negative regulator of trabecular bone remodelling and important for motor neuron development. Since haematopoietic cell maintenance and differentiation is dependent
Morphogenesis during multicellular development is regulated by intercellular signaling molecules as well as by the mechanical properties of individual cells. In particular, normal patterns of organogenesis in plants require coordination between growth direction and growth magnitude. How this is achieved remains unclear. Here we show that in Arabidopsis thaliana, auxin patterning and cellular growt
Background and purpose The Scandinavian Sarcoma Group (SSG) XIV protocol is based on experience from previous SSG trials and other osteosarcoma intergroup trials, and has been considered the best standard of care for patients with extremity localized, non-metastatic osteosarcoma. We analyzed the outcome in 63 consecutive patients. Patients and methods From 2001 through 2005, 63 patients recruited
New tools and forms of cooperation at the landscape level are needed in order for forestry and environmental conservation to co-exist in areas with many land owners. Awareness has existed for several years in Sweden that cooperation at the landscape level is essential for protecting areas of high environmental value. This awareness has come to expression in several projects and initiatives. One of
BACKGROUND: Conversion operations after vertical banded gastroplasty (VBG) are sometimes performed because of vomiting and/or acid regurgitation. Primary operation with gastric bypass (GBP) is known to reduce gastroesophageal reflux (GERD). Previous studies have not been designed to differentiate between the effects of the altered anatomy and of the ensuing weight loss. No series has reported data
Objective . Low density lipoprotein cholesterol (LDL-C) is an independent and modifiable risk factor for development of cardiovascular disease (CVD). Postprandial lipid metabolism has been linked to CVD, but little is known about the postprandial LDL-C profile in patients with type-2 diabetes (T2DM). We aimed to study the postprandial levels of LDL-C in T2DM patients. Material and methods . After
