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The initial evaluation of an Internet-based support system for audiologists and first-time hearing aid clients

Objectives: Audiologists provide professional contact and support between appointments to clients with hearing impairment using telephone and e-mail, but more advanced and flexible technological platforms are also possible. The present study aimed to evaluate the clinical application of an Internet-based support system for audiologists and their first-time hearing aid clients. Design: An Internet-

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer

Objective Clinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3′ UTR microRNA binding site, based on suggested associations with increased ovarian and breast cancer risk as well as with survival time. However, prior studies, emphasizing particular subgroups, were relatively small. Therefore, we comprehensively evaluated ovarian and breast canc

Production of bio-oil from lignin extracted from kraft black liquor by the Sunmembrane process

It is essential for the pulp and paper industry to utilize as much of the forest raw material as possible to achieve the sustainability goals and to increase the profit. The fibres that are liberated during the kraft pulping process are used for pulp production, while the rest of the components from the wood are mainly incinerated. Lignin is one major byproduct from the kraft pulping process. It h

Cellulosic Bioethanol Production

This chapter discusses some aspects of various separation technologies applied in bioethanol production from lignocellulosic materials. Bioethanol can be produced from lignocellulosic biomass using several different process configurations. The main energy-demanding process steps in lignocellulosic ethanol production are distillation to concentrate the ethanol, adsorption to remove the final conten

Validation of the thermophysiological model by Fiala for prediction of local skin temperatures

The most complete and realistic physiological data are derived from direct measurements during human experiments; however, they present some limitations such as ethical concerns, time and cost burden. Thermophysiological models are able to predict human thermal response in a wide range of environmental conditions, but their use is limited due to lack of validation. The aim of this work was to vali

Regional Branching Reconsidered : Emergence of the Fuel Cell Industry in European Regions

The literature on economic geography suffers from a lack of attention to the emergence of new industries. Recent literature on "regional branching" proposes that new industries emerge in regions where preexisting economic activities are technologically related to the emerging industry. This article provides a more grounded basis for the emerging literature on regional branching by confronting the

Copper induced root growth inhibition of Allium cepa var. Agrogarum L. involves disturbances in cell division and DNA damage

Copper (Cu) is considered to be an indispensable microelement for plants. Excessive Cu, however, is toxic and disturbs severalprocesses in the plant. The present study addressed the effects of ionic Cu (2.0 mMand 8.0mM) on mitosis, the microtubule cytoskeleton,and DNA in root tip cells of Allium cepa var. agrogarum L. to better understand Cu toxicity on plant root systems. The results indicated th

Application of in-house virtual protein database performed in genomic-proteomic combined research on heavy-metal stressed onion roots

Objectives To establish an in-house virtual protein database that can be employed in proteomic research on non-model plants. Results A total of 87,430 unigenes were obtained through transcriptome sequencing from onion roots. Of these, 24,305 unigenes were annotated and their nucleotide sequences of coding regions were translated into amino acid sequences. The corresponding 24,305 amino acid sequen

A spatially explicit agent-based modeling approach for the spread of Cutaneous Leishmaniasis disease in central Iran, Isfahan

Cutaneous Leishmaniasis (CL) is an endemic vector-borne disease in the Middle East and a worldwide public health problem. The spread of CL is highly associated with the socio-ecological interactions of vectors, hosts and the environment. The heterogeneity of these interactions has hindered CL modeling for healthcare preventive measures in endemic areas. In this study, an agent-based model (ABM) is

Fast Radon Transforms and Reconstruction Techniques in Seismology

The measurements conducted in tomography and seismology typically yield large multidimensional data sets. This in combination with the fact that the data may have an irregular structure makes it computationally prohibitive to use simple reconstruction methods directly. Hence, for inverse problems in computed tomography and seismology there is a demand for fast computational methods using high-perf

Fast Algorithms and Efficient GPU Implementations for the Radon Transform and the Back-Projection Operator Represented as Convolution Operators

The Radon transform and its adjoint, the back-projection operator, can both be expressed as convolutions in log-polar coordinates. Hence, fast algorithms for the application of these operators can be constructed by using FFT, if data is resampled at log-polar coordinates. Radon data is typically measured on an equally spaced grid in polar coordinates, and reconstructions are represented (as images

Response to biological treatment and subsequent risk of coronary events in rheumatoid arthritis

Objectives Whether the increased risk of comorbidities, such as cardiovascular disease, in rheumatoid arthritis (RA) can be reverted by particular antirheumatic therapies, or response to these, is unclear but of critical clinical importance. We wanted to investigate whether response to tumour necrosis factor inhibitors (TNFi) translates into a reduced risk for acute coronary syndrome (ACS). Method

Peak Bone Mass and Quantitative Ultrasound Bone Properties in Young Adulthood : A Study in the PEAK-25 Cohort of Women

Peak bone mass is normally reached in the third decade of life. Previously, in the population-based PEAK-25 cohort (n = 1061, age 25.5 ± 0.2), we demonstrated that bone mineral density in the population-based PEAK-25 cohort is comparatively high; therefore, this study aimed to determine if the calcaneus microarchitecture mirrored this. In the process, we describe normative quantitative ultrasound