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BACKGROUND: The role of ribonucleases in tuberculosis among people with human immunodeficiency virus (HIV; PWH) is unknown. We explored ribonuclease activity in plasma from PWH with and without tuberculosis.METHODS: Participants were identified from a cohort of treatment-naive PWH in Ethiopia who had been classified for tuberculosis disease (HIV positive [HIV+]/tuberculosis positive [tuberculosis+

A diet with low content of fermentable oligo-, di-, and monosaccharides and polyols (FODMAP) is established treatment for irritable bowel syndrome (IBS), with well-documented efficiency. A starch- and sucrose-reduced diet (SSRD) has shown similar promising effects. The primary aim of this randomized, non-inferiority study was to test SSRD against low FODMAP and compare the responder rates (RR = ∆T

Time to AIDS infection is longer with HIV-2, compared to HIV-1, but without antiretroviral therapy both infections will cause AIDS-related mortality. In HIV-2 infection, monitoring of antiretroviral treatment (ART) efficacy is challenging since a large proportion of HIV-2-infected individuals displays low or undetectable plasma RNA levels. Hence, quantification of cellular DNA load may constitute

There are seventeen million people in the world who are stateless, not considered as citizens by any state. They suffer due to the current function of citizenship in the nation-state system, occupying a legal space outside of the system, yet, their lives are very much blighted by the system itself. This research examines the possibility that global citizenship could be a means to address stateless

BACKGROUND: Despite advancements in surgical and anesthesia techniques, acute and persistent postoperative pain are still a common challenge. Postoperative pain has direct effects on individual patient care and outcome, as well as putting strain on limited health care resources. Several prediction methods for postoperative pain have been described. One such method is the assessment of pain during

The chapter discusses the use of citizenship and statelessness as a political tool by states during the turmoil in the Middle East North Africa during the "Arab Spring".

Mental health issues differ widely among individuals, with varied signs and symptoms. Recently, language-based assessments have shown promise in capturing this diversity, but they require a substantial sample of words per person for accuracy. This work introduces the task of Adaptive Language-Based Assessment (ALBA), which involves adaptively ordering questions while also scoring an individual’s l

This article challenges the concept of de facto (by fact) statelessness, often conceptualised as ineffective citizenship, from being included within the statelessness discourse. This is done by considering the nexus between de jure (by law) statelessness and de facto citizenship. The argument that if someone can have citizenship that is so ineffective they are de facto stateless is extended to con

Background Gender discrimination of women is often emphasized in work contexts, whereas less focus is on how men are discriminated against in social relationships. Gender discrimination in decisions of family relations, is essential to study as the contact between parent and child is commonly viewed as the most important relationship in people’s life, as well as being the most important aspect of

Rating scales are the dominating tool for the quantitative assessment of mental health. They are often believed to have a higher validity than language-based responses, which are the natural way of communicating mental states. Furthermore, it is unclear how difficulties articulating emotions-alexithymia-affect the accuracy of language-based communication of emotions. We investigated whether narrat

Psychological constructs are commonly quantified with closed-ended rating scales. However, recent advancements in natural language processing (NLP) enable the quantification of open-ended language responses. Here we demonstrate that descriptive word responses analyzed using NLP show higher accuracy in categorizing emotional states compared to traditional rating scales. One group of participants (N

Iran has yet to be the subject of research looking into the gaps in the nationality law, which, could create and perpetuate statelessness. There were however, several pre-identified populations, some members of which are believed to be affected by statelessness, as well as gender discrimination in the nationality law - which causes and increases the risk of rendering children stateless. Therefore,

The issue of statelessness has begun to receive attention from a legal perspective. While this work should be commended and continue this article argues that we should also remember that at its core statelessness is a human issue that deeply affects the lives of those who suffer from it. It causes and perpetuates, amongst other things, extreme poverty and human insecurity. Statelessness is still g

Milbrandt’s article highlights the need for increased debate surrounding the dire situation in which many stateless persons around the world find themselves.1 It provides a step in the right direction in that his article attempts to challenge the phenomena of statelessness and reduce its prevalence in the world. However, the idea put forward of global registration of stateless persons is criticall

Feeling in control of one’s environment and perceiving one’s home as meaningful have been found to be associated with health and well-being among older adults. As longitudinal studies of younger-old adults are lacking, this study aimed to investigate whether this association exists over time among older adults around retirement age. Longitudinal data from a random cohort of community-dwelling olde

OBJECTIVE: This systematic scoping review aimed to map the literature on the use of various nudging strategies to influence prescriber behavior toward reducing opioid prescriptions across diverse healthcare settings.METHODS: A systematic database search was conducted using seven electronic databases. Only articles published in English were included. A total of 2234 articles were identified, 35 of

Aerosol science is of utmost importance for both climate and public health research, and in recent years X-ray techniques have proven effective tools for aerosol-particle characterization. To date, such methods have often involved the study of particles collected onto a substrate, but a high photon flux may cause radiation damage to such deposited particles and volatile components can potentially

CONTEXT: Serious illness conversations help clinicians align medical decisions with patients' goals, values, and priorities and are considered an essential component of shared decision-making. Yet geriatricians at our institution have expressed reluctance about the serious illness care program.OBJECTIVES: We sought to explore geriatricians' perspectives on serious illness conversations.METHODS: We

BACKGROUND: In response to the Institute of Medicine (IOM) report, Dying in America, we undertook an institution wide effort to improve the experience of patients and families facing serious illness by engaging leadership and developing a program to promote the practice of generalist palliative care.MEASURES: The impact of the program was measured with process measures related to its' three parts.