Genetic susceptibility to insulin resistance is associated with lower adiposity in adults. Insulin resistance, and therefore adiposity, may alter sensitivity to Growth Hormone (GH). We aimed to determine the relationship between adiposity, genetic susceptibility to insulin resistance or insulin secretion, and response to GH treatment in short children born small for gestational age (SGA).

We report a strong prepulse dependence of the emission of X-rays from plasmas created by 150 fs Ti:sapphire laser pulses on solids. The laser pulses were focused onto plane samples of aluminium and vanadium with a main pulse power density of about 2.5 x 10(16) W cm(-2). By splitting off a portion of the main pulse we were able to generate a prepulse whose delay and intensity were variable relative

Abstract Pseudomonas aeruginosa is often found in chronic infections, including cystic fibrosis lung infections and those related to chronic wounds and venous ulcers. At the latter sites, P. aeruginosa can be isolated together with Staphylococcus epidermidis, and we have therefore explored the effect of clinical isolates and laboratory strains of P. aeruginosa strains on colonization by S. epiderm

Radiative lifetimes were determined for two short-lived states in neutral nitrogen. Following photodissociation and two-photon excitation employing the same UV source, excitation to higher states was performed with a distributed feedback dye laser (DFDL). The lifetimes were found to be tau(2p2 4d4D7/2) = 17(3) ns and tau(2p2 5s4P5/2) = 22(3) ns.

A compact fluorosensor with a fiber-optic measurement probe was developed, employing a continuous-wave violet diode laser as an exciting source and an integrated digital spectrometer for the monitoring of fluorescence signatures. The system has the dimensions 22x13x8 cm(3), and features 5 nm spectral resolution and an excellent detectivity. Results from measurements on vegetation and human premali

BACKGROUND: To date, the only estimate of the heritability of telomere length in wild populations comes from humans. Thus, there is a need for analysis of natural populations with respect to how telomeres evolve. METHODOLOGY/PRINCIPAL FINDINGS: Here, we show that telomere length is heritable in free-ranging sand lizards, Lacerta agilis. More importantly, heritability estimates analysed within, a

ABSTRACT: The microbiological composition of tobacco products was studied using culture and chemical analysis (of tobacco leaves) or chemical analysis only (tobacco and tobacco smoke). The chemical analyses utilized gas chromatography-tandem mass spectrometry for determining 3-hydroxy fatty acids, muramic acid, and ergosterol as markers of respectively lipopolysaccharide (LPS), peptidoglycan, and

The in vivo production of thromboxane and prostacyclin was studied by measurements of their major urinary metabolites in eight patients undergoing total hip arthroplasty. Specific methods based on gas chromatography-mass spectrometry were used to measure the urinary excretion of 2,3-dinor-TxB2 and 2,3-dinor-6-keto-PGF1 alpha. The excretion of these metabolites increased about 10-fold during the in

Preclinical studies support an anticancer effect of statin drugs, yet epidemiologic evidence remains inconsistent regarding their role in breast cancer primary prevention. Here, we report an updated analysis of the association between statin use and breast cancer incidence in the Nurses' Health Study (NHS) cohort. Postmenopausal NHS participants without a cancer history were followed from 2000 unt

Popular AbstractI början på 1990-talet drabbades Sverige av en mycket djup ekonomisk kris. Den svenska nittiotalskrisen uppfattades inte som en tillfällig konjunkturnedgång utan som symptom på grundläggande systemfel i Sveriges ekonomi. Många bedömare menade att den s.k. svenska modellen med stor välfärdsstat och höga skatter hade försämrat marknadsekonomins effektivitet och gjort att Sverige undeIn the early 1990s, Sweden was hit by a profound economic crisis. The Swedish crisis of the nineties was not perceived as a temporary recession, but rather as a fundamental and systemic fault in Swedish economy. Many commentators held that the Swedish model with a large welfare state and high taxes had impaired Sweden's economic performance. The aim of this thesis is to empirically assess the hypo

Writing the history of philosophy to some extent also implies expressing a certain philosophy of history. This article discusses a particular case of this dialectic, namely how one has related modern philosophy to pre-modern theological philosophies when writing the history of philosophy during the 20th Century. Is the emphasis put on the continuity or the interruptions between the two traditions,