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Hollow microspheres as targets for staged laser-driven proton acceleration

A coated hollow core microsphere is introduced as a novel target in ultra-intense laser-matter interaction experiments. In particular, it facilitates staged laser-driven proton acceleration by combining conventional target normal sheath acceleration (TNSA), power recycling of hot laterally spreading electrons and staging in a very simple and cheap target geometry. During TNSA of protons from one a

Characterization of Gastric Mucosa Biopsies Reveals Alterations in Huntington's Disease.

Weight loss is an important complication of Huntington's disease (HD), however the mechanism for weight loss in HD is not entirely understood. Mutant huntingtin is expressed in the gastrointestinal (GI) tract and, in HD mice, mutant huntingtin inclusions are found within the enteric nervous system along the GI tract. A reduction of neuropeptides, decreased mucosal thickness and villus length, as w

How to cannulate? A survey of the Scandinavian Association for Digestive Endoscopy (SADE) in 141 endoscopists

Cannulation of the papilla vateri represents an enigmatic first step in endoscopic retrograde cholangiopancreaticography (ERCP). In light of falling numbers of (diagnostic) ERCP and novel techniques, e. g. short-wire system, we were interested in the approach novice and experienced endoscopist are taking; especially, what makes a papilla difficult to cannulate and how to approach this. We devised

Evidence of a strong coupling between root exudation, C and N availability, and stimulated SOM decomposition caused by rhizosphere priming effects

Increased temperatures and concomitant changes in vegetation patterns are expected to dramatically alter the functioning of northern ecosystems over the next few decades. Predicting the ecosystem response to such a shift in climate and vegetation is complicated by the lack of knowledge about the links between aboveground biota and belowground process rates. Current models suggest that increasing t

Current−Voltage Characterization of Individual As-Grown Nanowires Using a Scanning Tunneling Microscope

Utilizing semiconductor nanowires for (opto)- electronics requires exact knowledge of their current−voltage properties. We report accurate on-top imaging and I−V characterization of individual as-grown nanowires, using a subnanometer resolution scanning tunneling microscope with no need for additional microscopy tools, thus allowing versatile application. We form Ohmic contacts to InP and InAs nan

Extending Languages by Leveraging Compilers: from Modelica to Optimica

Combining attribute grammars with object-oriented programming supports a new kind of declarative programming, allowing compilers to be built in a highly extensible manner. By leveraging a base compiler, extended languages can be supported at a relatively low cost. Recent work shows the applicability of the technique to general-purpose programming languages like Java. In this article, we illustrate

Agreement between TOAST and CCS ischemic stroke classification The NINDS SiGN Study

Objective: The objective of this study was to assess the level of agreement between stroke subtype classifications made using the Trial of Org 10172 Acute Stroke Treatment (TOAST) and Causative Classification of Stroke (CCS) systems. Methods: Study subjects included 13,596 adult men and women accrued from 20 US and European genetic research centers participating in the National Institute of Neurol

A search for extraterrestrial chromite in the late Eocene Massignano section, central Italy

The late Eocene may have been a period with an enhanced flux of extraterrestrial matter to Earth related either to a comet or an asteroid shower. The evidence comes from two very large and several medium-sized impact craters, at least two microtektite-microkrystite layers, and a stratigraphic interval with enhanced extraterrestrial He-3, all within the period ca. 36.3-34.3 Ma. Here, we show that t

Nordisk frikår och ambulans kämpade i andra boerkriget.

The Nordic support to the Boer people during the South African war 1899-1902 is a rather unknown history. Approximately 150 Scandinavian emigrants fought on the Boer side in the South African war and a sixth of them were killed at the battle of Magersfontein. The corps was followed by a Scandinavian ambulance formed by one Norwegian physician (Bidenkap), three Swedish nurses and six stretcher bear

Risk of Venous Thromboembolism in Patients With Rheumatoid Arthritis and Association With Disease Duration and Hospitalization

Context Recent reports suggest that rheumatoid arthritis (RA) may be a risk factor for venous thromboembolism (VTE), particularly in conjunction with hospitalization. Using hospitalization data to identify RA and VTE may identify patients when they are at elevated risk for other reasons, obscuring the incompletely understood underlying association between RA and VTE and leading to inappropriate in

Distributed reactions in highly turbulent premixed methane/air flames Part I. Flame structure characterization

Simultaneous planar laser-induced fluorescence (PLIF) measurements of a series of reactive scalars and Rayleigh scattering measurements of temperature, i.e. CH/CH2O/OH, HCO/CH2O/OH and T/CH2O/OH, and laser Doppler anemometry (LDA) measurements are carried out to characterize the flame/turbulence interaction in various regimes of turbulent combustion, including the laminar flamelet regime, the thin

Organic amendment and fungal species in combination can alter collembolan fitness

Organic material of different origin is commonly used as fertiliser in agricultural practices. Clover and wheat straw are here used to determine the importance of organic amendment for population development of fungal feeding collembolans. Two fungal species, Alternaria infectoria and Mucor hiemalis, were inoculated in three growth substrates, clover amended soil, straw amended soil and non-amende

Ecological applications of physically based remote sensing methods

Global monitoring of vegetation using optical remote sensing has undergone rapid technological and methodological development during the past decade. Physically based methods generally apply reflectance models for interpreting remotely sensed data sets. These methods have become increasingly important in the assessment of terrestrial variables from satellite-borne and airborne images. Products bas

Coulomb excitation of a Am-242 isomeric target: E2 and E3 strengths, rotational alignment, and collective enhancement

A 98% pure Am-242m ( K = 5(-), t(1/2) = 141 years) isomeric target was Coulomb excited with a 170.5-MeV Ar-40 beam. The selectivity of Coulomb excitation, coupled with the sensitivity of Gammasphere plus CHICO, was sufficient to identify 46 new states up to spin 18h in at least four rotational bands; 11 of these new states lie in the isomer band, 13 in a previously unknown yrast K-pi = 6(-) rotati

Hardware Implementation of an Iterative Sampling Rate Converter for Wireless Communication

Abstract in Undetermined This paper presents a new technique for fractional sample rate conversion based on an iterative Sinc (ISRC) method. The proposed algorithm was evaluated against the Farrow re-sampler, and performance simulation targeting different signal-to-noise ratios show the ISRC qualifies for application in reconfigurable terminals. The architecture was implemented in 65nm CMOS techno

Novel Endogenous Antimicrobial Peptides

Antimicrobial peptides serve as a first line of defence against invading microorganisms and are an essential part of our fast innate immune system. They are ancient molecules found in all classes of life. Antimicrobial peptides rapidly kill a broad spectrum of microbes and are immunomodulatory, i.e. having additional actions influencing inflammation and other innate immune responses. Results prese