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Background: Preload responsive postoperative patients with signs of inadequate organ perfusion are commonly assumed to be hypovolemic and therefore treated with fluids to increase preload. However, preload is influenced not only by blood volume, but also by venous vascular tone and the contribution of these factors to preload responsiveness in this setting is unknown. Based on this, the objective

Ice-marginal moraines are widely used as indicators of palaeoclimate in mountainous regions, yet the genetic processes of their formation remain incompletely understood. Here, we present new data on the geomorphology and sedimentology of annually formed moraine ridges in the foreland of Gornergletscher, Switzerland, with the aim of reconstructing the processes of their formation, assessing their p

Background: Patients with Dupuytren disease experience various activity limitations. Treatment aims to reduce finger joint contractures to improve hand function and activity performance. For assessing improvement different patient-centered measures have been used. The Canadian Occupational Performance Measure (COPM) was developed as an interview-based outcome measure to detect changes over time in

Mitochondria play essential roles in plant metabolism, supporting both development and stress responses. To maintain a healthy pool of mitochondria, several quality control systems are in place. Selected degradation of mitochondria by autophagy -mitophagy- has been extensively studied in yeast and animals, but information on mitophagy components in plants is limited. The ‘Friendly Mitochondria’ (F

This paper contributes to the literature with a methodology that helps identify the functions that constrain the overall performance of an innovation system, hence providing clear guidelines to policymakers on the direction of their interventions. This methodology relies on the notion of penalty for bottleneck, which is defined as the weakest link or the binding constraint that holds back system p

Nitrogenase is the only enzyme that can convert N2 into NH3. The reaction requires the addition of eight electrons and protons to the enzyme and the mechanism is normally described by nine states, E0–E8, differing in the number of added electrons. Experimentally, it is known that three or four electrons need to be added before the enzyme can bind N2. We have used combined quantum mechanical and mo

This paper presents LuMaMi28, a real-time 28GHz multi-user (MU) multiple-input multiple-output (MIMO) testbed. In this testbed, the base station has 16 transceiver chains with a fully-digital beamforming architecture (with different pre-coding algorithms) and simultaneously supports multiple user equipments (UEs) with spatial multiplexing. The UEs are equipped with a beam-switchable antenna array

Purpose: Caveolin-1 (CAV1) has been implicated in breast cancer oncogenesis and metastasis and may be a potential prognosticator, especially for non-distant events. CAV1 functions as a master regulator of membrane transport and cell signaling. Several CAV1 SNPs have been linked to multiple cancers, but the prognostic impact of CAV1 SNPs in breast cancer remains unclear. Here, we investigated CAV1

Site-specific public work, commissioned by NATUR North Atlantic Tales/Curated Place in collaboration with National Trust Formby. The work includes three sound installations: 'Spherical White with Diamond', stereo work (voice: Jez Dolan). 'Þytur', 9 mono-channels (voices: Maja Jantar, Angela Rawlings, Halla Steinunn Stefánsdóttir). 'The Shadowy Space Beneath', a stereo work, which builds on texts f

Image processing provides tools for image enhancement and extraction of information from images. Modification of the colour table allows for amplification of the contrast in certain pixel-value intervals while the contrast is suppressed in other intervals. This can in turn be used to selectively enhance the displayed image in intervals of special importance to the current problem. One of the most

Hempseed protein concentrate (HPC) was extracted from hempseed press cake with a protein content of 85.7% and co-extruded with oat fibre residue (OFR) to produce high-moisture meat analogues (HMMA) at different moisture contents (60, 63, 66%), screw speeds (500, 700, 900) and temperature profiles (40-70-110-130 °C and 40-70-120-150 °C). The effect of extrusion processing parameters such as moistur

In the last two decades, health promotion strategies have gained significant attention in end-of-life care contexts—engendering greater focus on community and informal care in policy and healthcare spheres in liberal welfare-states. The emergence of health-promoting palliative care (HPPC) in the Nordic context presents a unique challenge to the abiding social contract of care which emphasizes the

According to labor movement historian Axel Uhlén, two local conflicts in Malmö have created a huge interest all around Sweden (Uhlén, A. (1949) Facklig kamp i Malmö under sju decennier (Malmö: Framtiden), p. 259). The first labor dispute is the woodworker’s strike in 1890, called the Malmö revolt when thousands of people demonstrated in the streets and squares in the city center. Both local police

This book provides a comprehensive and interdisciplinary examination of courtroom ethnography. This collection gathers international researchers from a multitude of disciplines to explore three central themes: doing courtroom ethnography, ethnographic studies of the courtroom, and contemporary and critical aspects of courtroom ethnography. It highlights the nuances, negotiations, and issues that e

Introduction: Neoadjuvant chemotherapy (NAC) is an established treatment option for early breast cancer, potentially downstaging the tumor and increasing the eligibility for breast-conserving surgery (BCS). The primary aim of this study was to assess the rate of BCS after NAC, and the secondary aim was to identify predictors of application of BCS after NAC. Materials and methods: This was an obser