Eight furanocoumarins were isolated from a methanol extract of dried roots of Angelica dahurica. One of these, phellopterin, strongly (IC50 = 0.36 microM) inhibits the binding of [3H]diazepam to central nervous system benzodiazepine receptors in vitro, while the others, despite their structural similarities with phellopterin, are considerably less active.

The present report is about the fourth experiment in a series of five. This series concerns a longitudinal study of changing shapes of mind. Based on the assumption that mind is an emergent property of the processes that produce natural language expressions, mental development is discoverable through the Agent-action-Objective (AaO) mechanisms. The present study is focussing on the way in which th

Implants of commercially pure titanium and polytetrafluoroethylene (PTFE) were inserted in the rat abdominal wall for 1, 6 or 12 wk. The foreign body reaction was evaluated by immunohistochemical quantification of monocytes/macrophages and by the thickness of the foreign-body capsule. At all time intervals, the majority of interfacial cells were ED1-positive while ED2-positive cells were localized

We have investigated the electrical characteristics of Ti Schottky contacts with embedded Au nano-particles on various types of epilayers of SiC (4H- and 6H-SiC). From our current-voltage (I-V) and capacitance-voltage (C-V) measurements, we observed that Ti Schottky contacts with embedded Au nano-particles had 0.19 eV (n-4H-SiC) and 0.15 eV (n-6H-SiC) lower barrier height than those of particle fr

For mobile communication systems in the low-GHz range, CMOS has increasingly become the technology of choice, and the level of integration in mobile handsets has risen. The use of off-chip components, which increases the handset assembly time and costs, is preferably avoided. However, integrating a complete transceiver on a single chip leads to disturbances between building blocks. This imposes ne

Wave cycles, i.e. pairs of local maxima and minima, play an important role in many engineering fields. Many cycle definitions are used for specific purposes, such as crest-trough cycles in wave studies in ocean engineering and rainflow cycles for fatigue life prediction in mechanical engineering. The simplest cycle, that of a pair of local maximum and the following local minimum is also of interes

Popular Abstract in Swedish Var efterlystes brottslingar förr? I kyrkan! Var fick man reda på att äkta män övergivit sina hustrur? I kyrkan! Hur annonserades kommande auktioner? I kyrkan! Var tillkännagavs nya lagar och förordningar? Hur fick människor besked om var viktiga möten skulle äga rum? Hur visste man att landet var i krig och vad som hände under kriser av olika slag? Naturligtvis var detAs from 1686 it was decreed by law that all government regulations, orders, edicts and other information any government official wanted to make public, had to be read out to the people by the clergy from the pulpits of all churches in Sweden and Finland at the end of the sermon. The system of communication remained in full force until the end of the 19th century and was not finally abandoned until

Popular Abstract in Swedish Parkinsons sjukdom uppstår när celler som producerar signalsubstansen dopamin i hjärnan dör. Detta leder till att de drabbade patienterna blir stela, får långsamma rörelser, svårt att påbörja och avsluta rörelser och även skakningar i framförallt armar och händer. Idag finns inget sätt att bota sjukdomen. Dock finns det läkemedel som kan lindra symptomen. Den vanligasteThe main pathological feature in Parkinson's disease is the progressive loss of dopamine neurons in the midbrain, which in turn leads to the appearance of motor deficits such as akinesia/bradykinesia (loss/slowness of movements), rigidity, postural imbalance and tremor. To this day, there is no cure for the disease, but there are medications to relieve the symptoms. The gold standard medication is

The gene responsible for X-linked agammaglobulinemia (XLA) has been recently identified to code for a cytoplasmic tyrosine kinase (Bruton's agammaglobulinemia tyrosine kinase, BTK), required for normal B cell development. BTK, like many other cytoplasmic tyrosine kinases, contains Src homology domains (SH2 and SH3), and catalytic kinase domain. SH3 domains are important for the targeting of signal

For the period 1420-1960 we contrasted fire events reconstructed at 14 sites distributed over a 50 km x 50 km area in the central part of the Komi Republic (European Russia) with a set of tree-ring width chronologies of Scots pine (Pinus sylvestris L.), developed for the same area. Our aim was to infer common climatic information contained in treering variables and independently dated fire events

Actin- and myosin-like immunoreactivity is found in cells located in the theca externa of the follicle wall of the human ovary, and corresponding to previously observed myoid cells. The immunocytochemical observation provides direct structural evidence that non-vascular contractile cells are also present in the follicle wall in humans. As expected, perifollicular blood vessels showed a positive im