Filtyp
Enzymatic removal of blood group ABO antigens to develop universal red blood cells ( RBCs) was a pioneering vision originally proposed more than 25 years ago. Although the feasibility of this approach was demonstrated in clinical trials for group B RBCs, a major obstacle in translating this technology to clinical practice has been the lack of efficient glycosidase enzymes. Here we report two bacte
The results of Swanson and Avanta metacarpophalangeal joint arthroplasties in rheumatoid patients were compared in a prospective, randomized study of 30 patients (120 implants). At 2-year follow-up, grip strength was measured, hand function was assessed with the Sollerman test and the subjective outcome was determined with visual analogue scores. With both implants ulnar deviation and flexion defo
Some recent Swedish data on compartment fires are reviewed. Measured burning rates were as high as 7.7 A √ H kg/min where A is the opening area in m² and H is its height in m. A conventional power law is shown to relate the burning rate and the measured external flame length as well as does an empirical proportionality. The corrections to be allowed in both methods for the burning within the compa
Objectives. To evaluate the relationship between anti-neutrophil cytoplasmic antibody (ANCA) measured with two different methods and long-term clinical course in vasculitis. Design. Retrospective determination of ANCA with two different assays for detection of PR3-ANCA, conventional direct binding ELISA and capture ELISA using monoclonal antibodies against PR3. The 245 ANCA determinations were per
Popular Abstract in Swedish Hur förhåller sig ekonomisk tillväxt och fördelning till varandra när en ekonomi genomgår en strukturomvandlingsprocess? Denna klassiska frågeställning utgör det centrala problemet för denna avhandling. När Simon Kuznets i mitten av 1950-talet tog sig an samma fråga fann han med begränsade data att ekonomisk tillväxt förmodligen ökar inkomstklyftorna under en inledande What are the effects of growth on equality in a long-term perspective? What are the effects of different patterns of equality on subsequent growth? And why are these questions relevant for the understanding of economic development? These are the overriding questions posed in the dissertation. They are addressed in the context of long-term change from economic backwardness to modern economic growth
Apolipoprotein M (apoM) is a novel apolipoprotein present mostly in high-density lipoprotein (HDL) in human plasma. In the present study, we demonstrate that insulin, insulin-like growth factor I (IGF-I), and IGF-I potential peptide (IGF-IPP) significantly inhibits apoM expression, in a dose- and a time-dependent manner, in the human hepatoma cell line, HepG2 cells. Insulin-induced down-regulation
Abstracts of all master theses, made at the Division of Automatic Control, Lund Institute of Technology, are collected in this report. The theses, made from 1965 until July, 1, 1970, are ordered chronologically. The report is mainly written for other research institutes in the field of automatic control, industries, individual researchers as well as future candidates for master theses. The purpose
Phosphatidylethanol is formed by phospholipase D in animal cells exposed to ethanol. Previous reports have demonstrated that the degradation of phosphatidylethanol is slow, indicating that this lipid may be present in the cells after ethanol itself has disappeared. Accumulation of an abnormal alcohol metabolite may influence cellular functions. In the present study, cultivation of NG108-15 neurobl
Objective: The aim of this systematic literature review was to evaluate associations between different malocclusions, orthodontic treatment, and signs and symptoms of temporomandibular disorders (TMD). Materials and Methods: This review was part of a project at the Swedish Council on Technology Assessment in Health Care focusing on malocclusion and orthodontic treatment from a health perspective.
Aims To test the association between the immunoreceptor PD-1 (PDCD1) gene and Type 1 diabetes mellitus (T1DM). This gene has been reported to be associated with other autoimmune diseases such as systemic lupus erythematosus (SLE) as well as T1DM. Methods Genotyping of single nucleotide polymorphisms (SNPs) in the PDCD1 gene was performed using polymerase chain reaction-restriction fragment length
The evolution of the order Cetacea (whales, dolphins, porpoises) has, for a long time, attracted the attention of evolutionary biologists. Here we examine cetacean phylogenetic relationships on the basis of analyses of complete mitochondrial genomes that represent all extant cetacean families. The results suggest that the ancestors of recent cetaceans had an explosive evolutionary radiation 30-35
The insulin-secreting pancreatic beta cell is electrically excitable and changes in the membrane potential play an important role in coupling the metabolism of glucose (and other nutrient secretagogues) to the discharge of the insulin-containing granule. The application of the patch-clamp technique, which permits the recordings of the minute currents associated with the opening of individual ion c
An eight-band k.p theory that does not suffer from the spurious solution problem is demonstrated. It is applied to studying the electronic properties of InP and InAs free-standing nanowires. Band gaps and effective masses are reported as a function of size, shape, and orientation of the nanowires. We compare our results with experimental work and with other calculations.
Fluorescence spectra from different organs in rats and mice have been recorded to explore the potential of non-intrusive tissue diagnostics. The fluorescence was induced by a nitrogen laser that emitted at a wavelength of 337 nm. Optical multichannel techniques were used for the detection. Spectra are given from 19 different sites in Wistar/Furth rats, including an inoculated malignant tumour. The
An action spectrum for light induced carotenogenesis in V. agaricinum (Link) Corda (ATCC 24668) was obtained by exposing mycelial pads to monochromatic radiation. Action maxima occurred at 290 (main peak) and 390 nm and there was a minor peak at 483 nm. An interaction between the blue and UV light occurred. Blue light partly reversed the UV light induction of carotenogenesis when given after, but
Bladder function during filling and micturition is regulated by peripheral and central nervous and hormonal control systems. Micturition occurs in response to afferent signals from the lower urinary tract, and distention of the bladder wall is the primary stimulus. In the animal and human bladder, efferent adrenergic, cholinergic and nonadrenergic, noncholinergic (NANC) neurotransmission has been
The overall aim for the present study was to analyze the consequences for reading ability among the children of a computer supported self-regulated learning environment in grade two. By means of a quasi-experimental design in a natural setting, an experimental group (n=39) was compared to a control group from a national sample (n=3409) on reading comprehension. The statistical analyses showed that
The purposes are to validate the noninvasive parameters, QT interval, QT dispersion, Tpeak-Tend interval, and the activation recovery time (ART) for estimation of global dispersion of ventricular repolarization (DVR), and to investigate the changes of repolarization sequence and DVR by altered ventricular pacing sites. The material consisted of 12 patients (Study I) and two series healthy pigs wi
