The present paper concerns a performance-based fire safety analysis and design of a high-rise building. The resulting fire safety recommendations are compared with those specified by acceptable solutions in terms of the earlier prescriptive building code. The respective risk to life resulting from the analysis is compared and discussed. The benefit and need of using a risk based verification metho

Background: Several studies analyze how surgical delay affects patients with hip fracture. The aim of this study was to identify the causes of surgical delay and demographic characteristics in patients with hip fracture who had delays longer than 24 hours from admission to hospital. Methods: Quantitative retrospective register study of 484 patients was consecutively included during the period Nove

Specific immunotherapy (SIT) is the only treatment with proved long-term curative potential in patients with allergic disease. Allergen-specific IgE is the causative agent of allergic disease, and antibodies contribute to SIT, but the effects of SIT on aeroallergen-specific B-cell repertoires are not well understood.

Walking difficulties are common in neurological and other disorders, as well as among the elderly. There is a need for reliable and valid instruments for measuring walking difficulties in everyday life since existing gait tests are clinician rated and focus on situation specific capacity. The Walk-12G was adapted from the 12-item multiple sclerosis walking scale as a generic patient-reported ratin

This paper presents an investigation of rational agents that have limited computational resources and that can interact with their environments. We analyse how such agents can combine deductive reasoning using domain knowledge and inductive learning from past experiences, while remaining time-aware in a manner appropriate for beings situated in a dynamic universe. In particular, we consider how th

BACKGROUND: Reducing side effects of immunosuppressive regimens has become a priority in transplantation medicine because of the large number of patients and grafts that succumb to infection in the short term and cardiovascular disease in the long term. The Symphony study was a 12-month prospective, randomized, open-label, multi-centre, four parallel arm study that aimed to evaluate the safety and

PURPOSE: The aim of this study was to explore healthcare consumption in relation to more versus less knowledge concerning prescribed drugs among older people with functional dependency and repeated healthcare contacts, and to explore the determinants of more versus less knowledge METHODS: The sample comprised 63 persons (mean age 82.8 years). Data concerning use and knowledge about drugs, demograp

Abstract in Danish Artiklen argumenterer for, at vi alle fødes som mennesker, og at vi alle dør som mennesker; starttidspunktet er os givet; sluttidspunktet kender vi ikke, og det er i princippet uden ’aldersberegning’. Vores livshistorie er med til at skabe, forme og beskrive os; gennem hele livet og også ind i døden. Alder kan forstås og beskrives på mange måder, hvor vi ofte kategoriserer og it

BACKGROUND: The blood group antigens S and s are defined by amino acids Met or Thr at position 29, respectively, on glycophorin B (GPB). Commercial anti-s reagents are expensive to produce because of the scarcity of human anti-s serum. Our aim was to develop hybridoma cell lines that secrete reagent-grade anti-s monoclonal antibodies (MoAbs) to supplement the supply of human anti-s reagents. STUDY

Statins exert a number of anti-inflammatory and immunomodulatory effects in vitro. However, the immunomodulatory effects in vivo are less clarified. In the present study, we investigated whether simvastatin treatment changed the levels of autoantibodies against specific oxidized LDL (oxLDL) antigens as well as their association with leukocyte activation markers. Eighty volunteers with mild-to-mode