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The reactive vascular-injuring amino acid homocysteine was previously shown to be increased in plasma in diabetic patients with clinical signs of nephropathy. In this study, plasma homocysteine was measured in type 1 diabetic patients with normoalbuminuria (n = 22), microalbuminuria (n = 40) and proteinuria (n = 14) in order to investigate whether plasma homocysteine levels are increased already a
Background: Soluble E-selectin (sE-selectin) is a marker of activation of vascular endothelium. Objective: To examine serum levels of sE-selectin in a cohort of 85 patients with early rheumatoid arthritis (RA) followed up for five years. Methods: sE-selectin levels were assessed annually using an enzyme linked immunosorbent assay (ELISA) and related to simultaneously obtained clinical and laborato
2-Bromoethyl glycosides can easily and in high yields be transformed into sulfones by treatment with a suitable thiol followed by oxidation with mCPBA. The observation that the so formed sulfones were cleaved by treatment with NaOMe/MeOH was used to design a new safety catch linker for synthesis of glycoconjugates on solid support. (C) 2005 Elsevier Ltd. All rights reserved.
This study established the reliability of a novel upper-limb trajectory-tracking task for assessment of perceptual motor control in hemiparetic adults. Eleven persons with chronic poststroke hemiparesis (mean 58.6 months) and eleven nondisabled control subjects performed an elbow flexion-extension task against a low-resistance isotonic load at three speeds: 25degrees/s, 45degrees/s, and 65degrees/
The effects of small roundabouts on emissions and fuel consumption were evaluated using the “car-following” method in a before/after study. The results showed that at a roundabout replacing a signalised junction, CO emissions decreased by 29%, NOx emissions by 21%, and fuel consumption by 28%. At roundabouts, replacing yield regulated junctions, CO emissions increased on average by 4%, NOx emissio
Src homology 2 (SH2) domains recognize phosphotyrosine (pY)-containing sequences and thereby mediate their association to ligands. Bruton's tyrosine kinase (Btk) is a cytoplasmic protein tyrosine kinase, in which mutations cause a hereditary immunodeficiency disease, X-linked agammaglobulinemia (XLA). Mutations have been found in all Btk domains, including SH2, We have analyzed the structural and
Recension av Sofie Lene Bak, Jødeaktionen oktober 1943. Forestillinger i offentlighed og forskning
This thesis explores the ritual dimensions of the mortuary practices in the late Mesolithic cemeteries at Skateholm in Southern Sweden and Vedbæk-Bøgebakken in Eastern Denmark. With a combination of methods and theories that all focus on the ritual practices as action, a new approach to burials in archaeology is proposed. Special attention is given to the treatment of the body after death, which i
This thesis is a critique of the New Institutional Economics (NIE) in economic history. The focus is on explanations to the origin and development of capitalist institutions within NIE. After a methodological discussion in chapter 1 the author investigates into how well NIE succeeds in explaining capitalist institutions. In chapters 2 and 3, a conceptual critique of the theoretical bases of evolu
Objective: To examine and compare the adult outcome in a representative sample of hospitalized adolescent-onset psychoses including occupational and social aspects. Method: A total of 81 patients with a first episode of early-onset psychosis (before age 19 years) presenting to the University Hospital of Lund, Sweden, between 1982 and 1993 were followed up an average of 10.5 years (range 5.1-18.2)
Popular Abstract in Swedish Teknikutvecklingen leder till att vi får allt mer avancerade elektroniska medicinska implantat. Dessa spänner idag från den välkända hjärtpacemakern till avancerade hörselimplantat, hjärnstimulatorer och implanterbara medicinpumpar. Med de allt mer avancerade implantaten har också deras behov av att ta emot styrsignaler från utsidan av kroppen, och deras förmåga att sänWith the increased sophistication of medical implants, there is a growing need for flexible high-speed communication with the implant from outside the body. Today the communication is done by an inductive link between the implant and an external coil at a low carrier frequency. Extended range and communication speed are possible to achieve by increasing the carrier frequency and the bandwidth. One
Artikeln behandlar de svårigheter som uppstår i den offentliga debatten av konstutställningar när ämnet för utställningen är sexualiteter utanför den heterosexuella normaliteten. De bägge utställningar som behandlas, Donald Maders medverkan i Bjarne Mellgaards "Softcore" och Elisabeth Olsson-Wallins "Ecce Homo", väckte båda mycket starka reaktioner. Essän reder ut hur denna storm tar sin form i de
Popular Abstract in Swedish Döva barns begreppsbildning i matematik Denna studie tar utgångspunkt i frågan varför många döva barn har svårt att lära sig matematik. Studiens syfte är att belysa döva barns begreppsbildning i ämnet matematik genom att beskriva hur några döva barn uttrycker sig och agerar på väg mot förståelse av två centrala matematiska begrepp, nämligen multiplikation med heltal ochThe question why deaf children have difficulties in learning mathematics is the basis of this study. The aim of the study is to illuminate deaf children’s concept formation in mathematics by describing how some deaf children express themselves and act on their way towards understanding two basic concepts, the concept of multiplication with whole numbers and the concept of length. Theories develope
In the framework of the ESO Large Programme ``First Stars'', veryhigh-quality spectra of some 70 very metal-poor dwarfs and giants wereobtained with the ESO VLT and UVES spectrograph. These stars are likelyto have descended from the first generation(s) of stars formed after theBig Bang, and their detailed composition provides constraints on issuessuch as the nature of the first supernovae, the eff
The use of monoclonal antibodies (MAbs) in cytotoxic conjugates (radionuclides, toxins, or drugs) for targeting tumor cells is restricted due to toxicity in vital organs. Through improved tumor targeting, it is possible to administer larger amounts of such labeled MAbs, thus improving the ability to eradicate tumor cells without increased normal organ toxicity. Extracorporeal affinity adsorption t
