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A novel gas-filled detector for synchrotron radiation applications

We describe in this paper the performance under synchrotron radiation of a sealed gaseous detector, Vantec-1, operating at high pressure and less prone to discharges. It is consequently operating at high gain (>105) at high local counting rates up to 106 cps/mm2. To achieve these characteristics, a thin resistive layer is used on a glass plate between the mesh and the readout anode. The performanc

Anisotropy and transport properties of (Bi2Sr2CuO6+δ)m/(CaCuO2) n multilayers obtained by molecular beam epitaxy

Structural and transport properties of (Bi2Sr2CuO6+δ)m/(CaCuO 2)n superconducting multilayers, obtained by molecular beam epitaxy (MBE) alternately stacking m layers of Bi2Sr2CuO6+δ with n layers of CaCuO2, have been studied. Resistivity measurements and I-V characteristics in perpendicular and parallel magnetic fields have allowed to estimate the anisotropy parameter which results very low with r

Investigation of surface and sub-surface damage in high quality synthetic diamonds by X-ray reflectivity and grazing incidence in-plane diffraction

High quality single-crystal synthetic diamond is the most suitable material for selected X-ray optical applications in the latest generation X-ray light sources. Excellent heat handling properties, as well as low absorption, coupled with high perfection in the crystal bulk and very good surface quality, are crucial for such applications. In recent years, some progress has been made in the fields o

Bi-based superconducting multilayers obtained by molecular beam epitaxy

High temperature superconducting multilayers have been obtained depositing Bi2Sr2CuO6+δ (2201) and ACuO2 layers, where A is C a or Sr, by Molecular Beam Epitaxy (MBE) on M gO and SrTiO3 substrates. The samples, formed by a sequence of 2201/ACuO2 bilayers, have different thickness of ACuO2 layers while the thickness of the 2201 layers is kept constant. The surface structure of each layer has been m

Upper critical field and irreversibility line in Bi2Sr2CuO6+δ/CaCuO2 superconducting superlattices obtained by MBE

Resistivity measurements in external applied magnetic field up to 8.5T have been performed on Bi2Sr2CuO6+δ/CaCuO2 superconducting superlattices obtained by MBE. The magnetic field (H) vs. temperature (T) phase diagrams have been determined and the experimental data have been compared with that obtained in the case of Bi2Sr2CuO6+δ thin films deposited with the same technique. A reduction of the ani

Superconductivity in Bi2Sr2(Sr,Ca)CuOi multilayers obtained by molecular beam epitaxy

Bi-based high temperature superconduting multilayers have been obtained by Molecular Beam Epitaxy (MBE) using a deposition method which consists of both co-deposition and growth interruption techniques. We have studied two kinds of structures in which a layer of BizSrzCuOg+s (2201) is alternately stacked by an insulating layer of CaCuOi or SrCuOi in order to obtain 2201/CaCuO2 or IWl/SrCuO?. multi

Combining dense and sparse labeling in optical DNA mapping

Optical DNA mapping (ODM) is based on fluorescent labeling, stretching and imaging of single DNA molecules to obtain sequence-specific fluorescence profiles, DNA barcodes. These barcodes can be mapped to theoretical counterparts obtained from DNA reference sequences, which in turn allow for DNA identification in complex samples and for detecting structural changes in individual DNA molecules. Ther

Bi2Sr2CuO6+δ/ACuO2 (A = Ca,Sr) superconducting multilayers obtained by molecular beam epitaxy

Bi-based superconducting multilayers, consisting of Bi2Sr2CuO6+δ (2201) layers alternately stacked with CaCuO2 or SrCuO2 layers, have been deposited by Molecular Beam Epitaxy (MBE) using co-deposition and growth interruption techniques. In situ Reflection High Energy Electron Diffraction (RHEED) has been used to monitor the surface of the different layers giving evidence of a two-dimensional growt

Analysis and optimization by micro-beam X-ray diffraction of Al- GaInAs heterostructures obtained by Selective Area Growth for optoelectronic applications

Growth of AlGaInAs/InP heterostructures by Selective Area Metal Organic Vapour Phase Epitaxy is investigated in this paper using advanced characterization techniques and numerical modelling. Synchrotron radiation and X-Ray optics allow to have micro or sub-micro X-Ray probe. With this probe, it is possible to characterize our samples by X-Ray Diffraction on very restricted area. This technique was

The influence of domain permutations of an albumin-binding domain-fused her2-targeting affibody-based drug conjugate on tumor cell proliferation and therapy efficacy

Human epidermal growth factor receptor 2 (HER2) is a clinically validated target for breast cancer therapy. Previously, a drug-fused HER2-targeting affinity protein construct successfully extended the survival of mice bearing HER2-expressing xenografts. The aim of this study was to evaluate the influence of the number and positioning of the protein domains in the drug conjugate. Seven HER2-targeti

Short-term effect of induced alterations in testosterone levels on fasting plasma amino acid levels in healthy young men

Long term effect of testosterone (T) deficiency impairs metabolism and is associated with muscle degradation and metabolic disease. The association seems to have a bidirectional nature and is not well understood. The present study aims to investigate the early and unidirectional metabolic effect of induced T changes by measuring fasting amino acid (AA) levels in a human model, in which short-term

Importance of family history of colorectal carcinoma in situ versus invasive colorectal cancer : A nationwide cohort study

Background: The aim of this study was to explore the risk of invasive colorectal cancer (CRC) in relatives of patients with colorectal carcinoma in situ (CCIS), which is lacking in the literature. Patients and Methods: We collected data from Swedish family-cancer datasets and calculated standardized incidence ratio (SIR) and cumulative risk of CRC in family histories of CCIS in first- and second-d

An accelerated gradient-based optimization development for multi-reservoir hydropower systems optimization

Hydropower is one of the significant renewable energy resources. It is regularly requested at peak time steps to meet the load requirements of power systems resources allocation. Therefore, modeling the optimal operation of hydropower systems to maximize the entire energy production of reservoir systems can be a vital task for energy investment. Deriving optimal unknown decision parameters of thes

Laminar burning velocity of lean methane/air flames under pulsed microwave irradiation

Laminar burning velocity of lean methane/air flames exposed to pulsed microwave irradiation is determined experimentally as part of an effort to accurately quantify the enhancement resulting from exposure of the flame to pulsed microwaves. The experimental setup consists of a heat flux burner mounted in a microwave cavity, where the microwave has an average power of up to 250 W at an E-field in th

Political science : Moving from numbers to words in the case of Brexit

Quantitative text analysis is a growing research field in political science, whereas very few combine survey experiments with in-depth analysis of citizens’ word expressions. This chapter illustrates how a survey experiment and a latent semantic analysis are successfully combined in analyzing the 2016 EU referendum in Great Britain (Brexit). This example combines an analysis of semantic cluster ap

Betting on the underdog : The influence of social networks on vote choice

People are commonly expected not to waste their vote on parties with small probabilities of being elected. Yet, many end up voting for underdogs. We argue that voters gauge the popular support for their preferred party from their social networks. When social networks function as echo chambers, a feature observed in real-life networks, voters overestimate underdogs' chances of winning. We conduct v

Insurance strategic considerations in coalition-oriented systems : A consideration set model approach

During a vote-decision process, citizens elect between some of the parties – not all of them. In this paper, we explore a potential strategic reason to include an additional alternative in the consideration set. Drawing on research from the field of strategic voting, we study incentives to defect to a party at risk of falling below an electoral threshold in order to elect a winning coalition (”ins

Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis

Breast cancer metastasis accounts for most of the deaths from breast cancer. Identification of germline variants associated with survival in aggressive types of breast cancer may inform understanding of breast cancer progression and assist treatment. In this analysis, we studied the associations between germline variants and breast cancer survival for patients with distant metastases at primary br

Junctional Adhesion Molecule 3 Expression in the Mouse Airway Epithelium Is Linked to Multiciliated Cells

Tight-junction (TJ) proteins are essential for establishing the barrier function between neighbor epithelial cells, but also for recognition of pathogens or cell migration. Establishing the expression pattern and localization of different TJ proteins will help to understand the development and physiology of the airway. Here we identify that the junctional adhesion molecule 3 (Jam3) expression is r

Distribution of planar cell polarity proteins in the developing avian retina

Planar cell polarity (PCP) is evolutionary conserved and play a critical role in proper tissue development and function. During central nervous system development, PCP proteins exhibit specific patterns of distribution and are indispensable for axonal growth, dendritogenesis, neuronal migration, and neuronal differentiation. The retina constitutes an excellent model in which to study molecular mec