The tryptophan to kynurenine ratio (Trp/Kyn) has been proposed as a cancer biomarker. Non-invasive topical sampling of Trp/Kyn can therefore serve as a promising concept for skin cancer diagnostics. By performing in vitro pig skin permeability studies, we conclude that non-invasive topical sampling of Trp and Kyn is feasible. We explore the influence of different experimental conditions, which are

There is increasing evidence suggesting a role of intestinal dysfunction in a number of autoimmune diseases. Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease with a documented increased level of intestinal inflammation, whereas multiple sclerosis (MS) is an organ-specific autoimmune disease known to exhibit increased intestinal permeability. In this study we determine to what exte

Background: Ovarian torsion is a gynecological surgical emergency whose diagnosis remains a challenge. Torsion occurs most frequently in women of reproductive age. It is usually associated with the presence of benign masses in the ovary, as malignant tumors are less frequent and less prone to undergo torsion. Case presentation: We report the case of a 17-year-old Caucasian patient who presented to

Recension av Dirk Gindts bok Tennessee Williams in Sweden and France 1945–1965 (2019)

The aim of the study was to compare background characteristics, microbiology and outcome of patients with right-sided and left-sided intravenous drug use (IDU) associated infective endocarditis (IE). A nationwide retrospective study using the Swedish Registry on Infective Endocarditis between 2008 and 2019 was conducted. A total of 586 people with IDU-IE were identified and divided into left-sided

This is an analysis of the recently proposed amendments in the Swedish asylum legislation under the prism of intra-EU solidarity. The main issue raised is the extent to which an EU state may downgrade protection and block entry in its territory to asylum seekers and refugees without proper identification documents with the motivation that this might evoke more EU solidarity and responsibility.

Microbial resistance to antibiotics is a growing challenge to human health. Recent evidence has indicated that antibiotic resistance can be co-selected for by exposure to heavy metals in agricultural soils. It remains unknown if this is a concern in other environments contaminated by metals. We here investigated soil microbial activities, composition and tolerance to heavy metals and antibiotics i

Sera of eight unselected adult patients with acute myelogenous leukemia obtained before and after chemotherapy were repeatedly tested for specific complement‐dependent cytotoxicity against autochthonous peripheral white blood cells from the acute leukemia stage and from the remission stage, respectively. Complement‐dependent cytotoxicity against white blood cells from the acute leukemia stage was

Staphylococcus aureus, strain Cowan I, contains a cell‐wall substance, protein A, which combines with the Fc part of IgG in most mammalian species. It can therefore be used as a solid‐phase immunoabsorbant for elimination of the reacting immunoglobulins. Since it has been shown that Cowan I could absorb out the blocking activity of sera from rats bearing isografts of polyoma‐virus‐induced sarcomas

The effects of cyclophosphamide (CY) on tumor immunity against isografts of rat sarcomas induced by polyoma virus were studied using in vitro techniques. Groups of sarcoma‐bearing animals received CY (250 mg/kg intraperitoneally 11 days after isografting) CY (150 mg/kg IP 8 days after isografting), or IP injections of 0.9% NaCl. In control rats tumor growth was progressive. All CY‐treated animals

A 24-hour bioblitz was performed by employees in the immediate surroundings of the Biological Institute in the city of Lund, South Sweden, on the 15th of June 2018. It produced 928 taxa, 411 of which were insects. Six species of Hymenoptera Parasitica were new to Sweden: Tumidiclava bimaculata (Blood), Lathromeris germanica (Girault), Aprostocetus crassiceps Graham, Quadrastichus anysis (Walker), Insect finds during the bioblitz of the Department of Biology in Lund in June 2018A 24-hour bioblitz was performed by employees in the immediate surroundings of the Biological Institute in the city of Lund, South Sweden, on the 15th of June 2018. It produced 928 taxa, 411 of which were insects. Six species of Hymenoptera Parasitica were new to Sweden: Tumidiclava bimaculata (Blood), Lathromeris ge

Nestbuilding of the hairy-footed flower bee Anthophora plumipes (Pallas) (Apidae) in a home-made bee hotel with a loam mixture, in a garden in Lund, Scania, is reported. Observations of behaviour and the ecology of the species are described.

The physical and chemical properties of semiconductor nanowires are significantly influenced by their surface structure and morphology. This can be understood in that surfaces make out a much larger part of the total structure as compared to macroscale objects. An immediate consequence is that the lack of surface control can result in poor performance and reproducibility of any nanowire device. It