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Encounters and interactions between healthcare professionals and patients are central in healthcare services and delivery. Encountering persons who frequently use psychiatric emergency services (PES), a complex patient group in a complex context, may be particularly challenging for healthcare professionals. The aim of the study was to explore healthcare professionals’ experiencesof such encounters
Objectives: The use of rituximab (RTX) in multiple sclerosis (MS) is a rapidly increasing choice of disease-modifying therapy. Efficacy outside specialized university hospital-based care is not yet systematically investigated. Our aim was to evaluate off-label RTX treatment for MS at a general hospital in Sweden. Materials and Methods: Subjects with definite MS with at least one rituximab infusio
Introduction: In the past decade there have been many attempts to improve systemic treatment and thus the outcome of patients with ovarian cancer. However, neither the sequential addition of non cross-resistant drugs to standard chemotherapy comprising carboplatin and paclitaxel, nor triplet combination therapies with conventional chemotherapeutic drugs have improved outcomes. Instead, such approa
The purpose of this article is twofold: First to discuss three misconceptions in the debate on climate policies: i) that de-growth is necessary, ii) that the market economy is part of the problem rather than part of the solution to climate change, and iii) that the only policy tool needed is to price carbon emissions. Second, to argue that climate change cuts across traditional policy areas and th
Machinery prices are a crucial part of the history of catching up, technological progress and the industrial revolution diffusion. However, the efforts to obtain an international price for capital goods have been scattered and the majority of the works dealing with this phenomena had a national scope mainly . In this paper, the authors have done an effort to homogenise the different national machi
Objective: To study the long-term effects of a workplace intervention in addition to structured physiotherapy regarding self-reported measures in patients with acute/subacute neck and/or back pain. Design: WorkUp – a cluster-randomised controlled trial in 32 primary care centers in Sweden, from January 2013 through December 2014 (ClinicalTrials.gov ID: NCT02609750). Intervention: Structured physio
Skönlitterär bok för åldern 9-12 år.Vad är egentligen mod? Kan man lära sig att bli modig? Det frågar sig Malva, elva år, när hon inte lyckas stå inför hela klassen i skolan och berätta om sitt sommarlov. Inte ett vettigt ord får hon fram. De andra barnen fnissar och fröken suckar. En trasig flaskpost blir Malvas räddning. Genom det mystiska receptet i flaskan blir hon mindre än en tumme. Och sugs
Background: There are limited data regarding efficacy of abatacept treatment for rheumatoid arthritis (RA) outside clinical trials. Quality registers have been useful for observational studies on tumor necrosis factor inhibition in clinical practice. The aim of this study was to investigate clinical efficacy and tolerability of abatacept in RA, using a national register. Methods: RA patients that
We present a novel family of deep neural architectures, named partially exchangeable networks (PENs) that leverage probabilistic symmetries. By design, PENs are invariant to block-switch transformations, which characterize the partial exchangeability properties of conditionally Markovian processes. Moreover, we show that any block-switch invariant function has a PEN-like representation. The DeepSe
Rivers discharge a notable amount of dissolved Fe (1:5×109 mol yr-1) to coastal waters but are still not considered important sources of bioavailable Fe to open marine waters. The reason is that the vast majority of particular and dissolved riverine Fe is considered to be lost to the sediment due to aggregation during estuarine mixing. Recently, however, several studies demonstrated relatively hig
Land-use change is a major driver of biodiversity loss worldwide. Although biodiversity often shows a delayed response to land-use change, previous studies have typically focused on a narrow range of current landscape factors and have largely ignored the role of land-use history in shaping plant and animal communities and their functional characteristics. Here, we used a unique database of 220,000
A continuous-wave (CW) Scheimpflug underwater multi-spectral lidar system was constructed to monitor aquatic fauna with spatial, spectral, and temporal resolution. Utilizing a 1 W 414 nm diode laser and a detection set-up with a reflective grating, measurements of shrimp pleopod movements at fixed range, and the swimming of small fish trapped in a clear tube were performed in a 5 m ×0.6 m ×0.6 m w
This paper experimentally investigates heat dissipation of a heat pipe with phase change materials (PCMs) cooling in a multiple heat source system. Two heat sources are fixed at one end of the heat pipe. Considering that a heat sink cannot dissipate all the heat generated by two heat sources, various PCMs are used due to a large latent heat. Different materials in a container are wrapped outside o
Secondary organic aerosol (SOA) forms a major part of the tropospheric submicron aerosol. Still, the exact formation mechanisms of SOA have remained elusive. Recently, a newly discovered group of oxidation products of volatile organic compounds (VOCs), highly oxygenated organic molecules (HOMs), have been proposed to be responsible for a large fraction of SOA formation. To assess the potential of
Using particle-in-cell simulations, we demonstrate an improvement of the target-normal-sheath acceleration (TNSA) of protons in non-periodically nanostructured targets with micron-scale thickness. Compared to standard flat foils, an increase in the proton cutoff energy by up to a factor of two is observed in foils coated with nanocones or perforated with nanoholes. The latter nano-perforated foils
Anisotropic dynamics on the colloidal length scale is ubiquitous in nature. Of particular interest is the dynamics of systems approaching a kinetically arrested state. The failure of classical techniques for investigating the dynamics of highly turbid suspensions has contributed toward the limited experimental information available up until now. Exploiting the recent developments in the technique
The majority of studies in the field of timing and time perception have generally focused on sub- and supra-second time scales, specific behavioral processes, and/or discrete neuronal circuits. In an attempt to find common elements of interval timing from a broader perspective, we review the literature and highlight the need for cell and molecular studies that can delineate the neural mechanisms u
