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Reduced inhibition of enzymatic hydrolysis of steam-pretreated softwood

Softwood constitutes the main source of lignocellulosic material in Sweden which can be used for ethanol production from renewable resources. To make the biomass-to-ethanol process more economically feasible, it is preferable to include the sugar-rich prehydrolysate, i.e. the liquid obtained after the pretreatment step, in the enzymatic hydrolysis of the solid fraction. This study shows that the p

The State in European Employment Regulation

The aim of the paper is to examine the changing role of the state in employment regulation in an environment that has become more market-driven and Europeanised since the introduction of the European Monetary Union (EMU) and the European Employment Strategy (EES). The point of departure is a general discussion of the role of the state in capitalist development and a review on the recent debate on

Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells.

Aromatic 3,3'-diesters of thiodigalactoside were synthesized in a rapid three-step sequence from commercially available thiodigalactoside and evaluated as inhibitors of cancer- and immunity-related galectins. For each of galectins-1, -3, -7, and -9N-terminal domain, aromatic 3,3'-diesters of thiodigalactoside were found to have affinities in the low micromolar range, which represents a 7-70 fold e

A non-existence result for the Ginzburg-Landau equations

We consider the stationary Ginzburg–Landau equations in Rd, d=2,3. We exhibit a class of applied magnetic fields (including constant fields) such that the Ginzburg–Landau equations do not admit finite energy solutions.

A model of triploid endosperm evolution driven by parent-offspring conflict

The parental investment in angiosperms comprises the endosperm, a nutrient reserve that is used during seed development. The endosperm contains genes from both parents. The most common endosperm form is the 3n Polygonum-type with more maternal genetic influence than paternal, i.e. with two maternal nuclei and one paternal nucleus. The evolutionary original state is thought to be a diploid endosper

Moisture diffusivities evaluated at high moisture levels from a series of water absorption tests

This paper presents measured moisture diffusivities for sedimentary calcareous sandstone, lime silica bricks, bricks, and autoclaved, aerated concrete. The moisture diffusivities were calculated from the relation between the water sorption coefficients and the initial water content in the specimen before testing. The method used is based on Boltzmann transformation. The relation between the water

Census of binaries - The big picture

Gaia will observe huge numbers of binaries with a large range of periods. The present contribution tries to present some estimates of the expected number of detections and/or orbit determinations, based on simplified but large-scale simulations. The simulations have to model both a Galaxy with binaries, the instrument and observations, and the reduction programs. As in previous studies, there are

Neuropeptide Y co-exists with vasoactive intestinal polypeptide and acetylcholine in parasympathetic cerebrovascular nerves originating in the sphenopalatine, otic, and internal carotid ganglia of the rat

Neuropeptide Y co-exists with noradrenaline in the majority of the sympathetic nerves supplying cerebral blood vessels. However, after sympathectomy in the rat the number of cerebrovascular neuropeptide Y nerve fibers are only reduced in number despite a complete disappearance of the adrenergic markers. The origin of these non-sympathetic neuropeptide Y fibers was studied by nerve transections and

Fisher information analysis for two-dimensional microwave tomography

In this paper, a Fisher information analysis is employed to establish some important physical performance bounds in microwave tomography. As a canonical problem, the two-dimensional electromagnetic inverse problem of imaging a cylinder with isotropic dielectric losses is considered. A fixed resolution is analysed by introducing a finite basis, i.e., pixels representing the material properties. The

KSHV complement control protein mimics human molecular mechanisms for inhibition of the complement system.

Kaposi's sarcoma-associated human herpesvirus (KSHV) is thought to cause Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease. Previously, we reported that the KSHV complement control protein (KCP) encoded within the viral genome is a potent regulator of the complement system; it acts both as a cofactor for factor I and accelerates decay of the C3 convertases (Spiller,

Islet constitutive nitric oxide synthase and glucose regulation of insulin release in mice

We have studied, by a combined in vitro and in vivo approach, the relation between the inhibitory action of N(G)-nitro-l-arginine methyl ester (L-NAME), a selective inhibitor of nitric oxide synthase (NOS), on the activity of islet constitutive NOS (cNOS) and glucose regulation of islet hormone release in mice. The cNOS activity in islets incubated in vitro at 20 mM glucose was not appreciably aff

A Model-Based Approach to Determine the Design Space of Preparative Chromatography

A dream of many pharmaceutical companies is to be able to register a large design space with the regulatory agencies. The problem is that this will require both time and money, so an intelligent method of validating a design space is needed. The design space should only cover operating points at which the process runs optimally. This means that the process should be optimized for different process

Compact fiber-optic fluorosensor using high-power continuous-wave violet diode laser

In this work a compact fluorosensor has been built for point-monitoring and imaging applications. The instrument has been applied in fluorescence studies on green vegetation and on malignant tissue. The instrument is based on a violet diode laser, an integrated spectrometer and optical fibers for light delivery and collection of the fluorescence signal. This combination makes the system very compa

Closure of atrial septal defect in the adult. Cardiac remodeling is an early event.

Background: Study aimed to describe the extent and the temporal profile of cardiac remodeling after atrial septal defect closure in the adult. Methods: Prospective and longitudinal echocardiographic assessment of right and left heart size before and after (1 day-1 week/1/4/12 months) surgical or catheter-based atrial septal closure in 39 adults (age 54 15 years). Results: Right ventricular and atr

Improving the rainbow attack by reusing colours

Hashing or encrypting a key or a password is a vital part in most network security protocols. The most practical generic attack on such schemes is a time memory trade-off attack. Such an attack inverts any one-way function using a trade-off between memory and execution time. Existing techniques include the Hellman attack and the rainbow attack, where the latter uses different reduction functions (