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The molecular basis for the effectiveness of arginine-rich cell penetrating peptides (ARCPPs) traversing a cell membrane barrier is not well established. The fact that a threshold concentration of ARCPPs is required for efficient translocation in model membranes suggests cooperative action by ARCPPs. We used umbrella sampling simulations to calculate the free energies for membrane pore formation.

This qualitative study explored how some working Austrians experienced and coped with changes in their daily occupations after becoming informal carers of persons who had had a stroke. The study provides insights into the working carers' occupational experiences and strategies during a period of pronounced life changes.

Popular Abstract in English News about global warming, discussions about alternative fuels such as natural-gas and biogas, and commercials about gas engines sound familiar to the most people living in modern societies. Why global warming is important? What is the role of natural-gas engines in this subject? Are natural-gas engines efficient? Do they perform as well as diesel engines? If not, why? Most heavy-duty engines are diesel operated. Severe emission regulations, high fuel prices, high technology costs (e.g. catalysts, fuel injection systems) and unsustainably in supplying fuel are enough reasons to convenience engine developers to explore alternative technologies or fuels. Using natural gas/biogas can be a very good alternative due to the attractive fuel properties regarding emissio

A high precision five rotation-axes polarimeter using transmission multilayers as polarizers and reflection multilayers as analyzers has been designed and manufactured. To cover the extreme ultraviolet regime, Mo/Si, Cr/C, Sc/Cr, and W/B4C multilayers for transmission and reflection have also been designed and produced. The polarimeter mechanics is supported on a hexapod to simplify the alignment

This engineering design guideline is intended for wood in outdoor above ground applications, i.e. use class 3 according to EN 335. It is based on a prescribed limit state for onset of decay during a reference service life of 30 years. Onset of decay is defined as a state of fungal attack according to rating 1 in EN 252. The approach is to determine the climate exposure as a function of geographica

A cotton skin and Gore-Tex skin were designed for thermal manikin "Tore" to simulate different sweating styles (wet cotton skin inside and Gore-Tex outside to simulate sweating style of thermal manikin "Walter", and Gore-Tex skin inside with wet cotton skin outside to simulate sweating style of thermal manikins "Newton". The evaporative resistances of two skin combinations with clothing ensembles

Gliomas are the most common primary brain tumor, and their treatment is still a challenge. Here, we evaluated the antiproliferative effect of a novel combination of two potent oxidative stress enhancers: menadione (M) and sodium orthovanadate (SO). We observed both short-term and prolonged growth inhibitory effects of M or SO alone as well as in combination (M:SO) on DBTRG.05MG human glioma cells.

Gaussian Mixture Model (GMM)-based predictive coding of line spectral frequencies (lsf's) has gained wide acceptance. In such coders, each mixture of a GMM can be interpreted as defining a linear predictive transform coder. In this paper we optimize each of these linear predictive transform coders using Kalman predictive coding techniques to present GMM Kalman predictive coding. In particular, we

Följande sammanställning utgörs av en materialpresentation av och en katalog över Göteryds hällkistor i Kronobergs län, Småland. Den är uppdelad i två delar där materialpresentationen utgörs av del 1 och katalogen av del 2. Hällkistmaterialet omfattar även en genomgång av hällkistorna i hela Kronobergs län. Materialpresentationen, del 1, innehåller målsättningen med arbetet med hällkistorna, en ge

In 2003 the joint European effort to design a European Spallation Source (ESS) resulted in a set of reports, and in May 2009 Lund was agreed to be the ESS site. The ESS Scandinavia office has since then worked on setting all the necessary legal and organizational matters in place so that the Design Update and construction can be started in January 2011, in collaboration with European partners. The

Objectives: The aim of this study was to analyse lung function test determinants for long-term mortality after standard endovascular aneurysm repair (EVAR) for infrarenal abdominal aortic aneurysm (AAA). Design: Retrospective analysis. Materials: Three-hundred and four consecutive patients treated electively with EVAR (Zenith (R) stent grafts, Cook) between May 1998 and February 2006 were prospect

The energy balance at most surface-atmosphere flux research sites remains unclosed. The mechanisms underlying the discrepancy between measured energy inputs and outputs across the global FLUXNET tower network are still under debate. Recent reviews have identified exchange processes and turbulent motions at large spatial and temporal scales in heterogeneous landscapes as the primary cause of the la

Agricultural emissions in Europe are important to several atmospheric transport-related environmental issues. These include local and regional air quality problems, such as PM exposure, eutrophication and acidification, toxics and contribution to greenhouse gas emissions, resulting in a number of environmental impacts. Over Europe, agricultural emissions are variable in space and time and the cont

Multi-antenna design in compact mobile handsets at frequency bands below 1 GHz is very challenging, since severe mutual coupling is commonly induced by simultaneous excitation of the chassis’ fundamental dipole mode by more than one antenna element. To address this problem, a novel multi-antenna design approach is proposed herein to obtain efficient and uncorrelated antennas. By manipulating the c

The vicicitudes of today's global economy and increasing awareness of employee well-being call for relevance of psychological capital. The study set out to review and explore the importance of psychological capital and has suggested a double-loop framework to explain the mechanisms of psychological capital.

Recent studies indicate that defective activity of complement factor H (FH) is associated with several human diseases, suggesting that pure FH may be used for therapy. Here, we describe a simple method to isolate human FH, based on the specific interaction between FH and the hypervariable region (HVR) of certain Streptococcus pyogenes M proteins. Special interest was focused on the FH polymorphism