Proteinase-activated receptors (PARs) are activated by proteolytic removal of a short amino terminal peptide, thus exposing a new amino terminus that functions as a tethered ligand that activates the receptor. With the aim to identify and study potential activators of PAR-2 we have developed a new method to measure proteolytic cleavage of PARs. PAR-2 was tagged with the insulin C-peptide that upon

Background - Contrast-enhanced steady state free precession (CE-SSFP) and T2-weighted short tau inversion recovery (T2-STIR) have been clinically validated to estimate myocardium at risk (MaR) by cardiovascular magnetic resonance while using myocardial perfusion single-photon emission computed tomography as reference standard. Myocardial perfusion single-photon emission computed tomography has bee

The main aim of this paper is to discuss how, within a sociocultural perspective, to design and conduct interviews for studying information literacy in everyday life. A methodological framework combining a sociocultural perspective with a narrative interview method is developed, in which visual tools are used to engage interviewees as active participants in the interview situation. This method was

Background: Ultraviolet (UV)-curing nail polishes based on acrylates or methacrylates are currently also available for non-professional use. The Swedish Medical Products Agency recently prohibited one brand of UV-curing polish, because several consumers reported undesirable effects after using it. Objectives: To investigate whether consumers with undesirable effects after using the UV-curing nail

Background Increased knee abduction during weight-bearing activities is suggested to be a contributing factor for the high knee injury risk reported in women. However, studies investigating gender difference in knee abduction are inconclusive. Objective To systematically review gender-differences in knee abduction during weight-bearing activities in individuals with or without knee injury. Methods

Background: The globalisation of the economy and the labour markets has resulted in a growing proportion of individuals who find themselves in a precarious labour market situation, especially among the young. This pertains also to the Nordic countries, despite their characterisation as well developed welfare states with active labour market policies. This should be viewed against the background of

Objectives. The aim of the study was to investigate if adequate preservation of coronary artery endothelium-dependent relaxation and contractility may be obtained after 8 hours of non-ischemic heart preservation. Design. Porcine hearts were perfused for 8 hours at 8 °C, either in cycles of 15 minutes perfusion and 60 minutes non-perfusion, or by continuous perfusion. The perfusate consisted of a c

It is worth taking a closer look at the Court of Justice judgment in Selex Sistemi Integrati Spa v. Commission. The Court of Justice’s judgment adds important elements with regard to the definition of undertaking, as it partly redefines the boundaries between the exercise of public authority and economic activity.

The concept of patient-focused care aims to provide an environment in which the healthcare team focuses on the individual patient’s needs. In order to increase our understanding of how nurses perceive and conduct patient-focused care, the issue needs to be studied in various contexts. The aims of the study were to explore nurses’ descriptions of their patient-focused care, what took place during o

The paper investigates the different regimes for the exchange of information in cross-border competition cases. It argues that the co-operation and information exchange mechanisms in competition cases established by Regulation 1/2003 have been overtaken by the means provided by the European Evidence Warrant which was developed under the former third Pillar (Co-operation in Criminal Matters). Moreo

The paper examines whether the changes in the objectives of the EU means a change in the competition acquis. A three step analysis leads to the conclusion that this has not to be expected. Initially the status of competition in the constitutional hierarchy under the old EC Treaty is examined before the detailed changes under the Lisbon Treaty are set out. The paper then investigates whether the am

This paper gives an introduction into the concepts of competition law and its economic foundations. The main focus of the paper are the substantive provisions of the Malaysian Competition Act. The paper first sets out the basic economic models underpinning the competition law analysis. In a second step the paper examines the substantive provisions of the Competition Act while making due reference