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Objectives ‒ The STarT Back screening Tool (SBT) captures patients with low back pain (LBP) at risk of worse prognosis. However, the SBT does not include assessment of multisite and chronic widespread pain (MS-CWP). The aim was to study the differences in prognostic factors in patients with LBP classified according to SBT or SBT in combination with MS-CWP, and the 1-year outcome regarding visits t

Imaging the orientations of crystallites in bone requires the usage of synchrotron X-ray radiation, which is a limited resource for researchers. Thus scans have historically been limited to either small regions or few samples. In the present study, we scan 16 full frontal cross sections of mouse femora. This makes it possible to study structure, orientation, and composition, statistically across m

In this study, we perform paleontological and sedimentary research of three sections, Tianjiayuanzi, Jiulongwan, and Qinglinkou, located within the carbonate platform of the Huangling Anticline in the eastern Three Gorges area, Yichang City, Hubei Province. The aim is to investigate the spatial distribution patterns of microfossils in silicified bands from the lower Member III of the Doushantuo Fo

Mycelial residues, also known as fungal necromass, represent a substantial fraction of soil organic matter (SOM) pools in terrestrial ecosystems worldwide. Although microbial decomposers are increasingly recognised as key drivers of fungal necromass carbon stock formation, the diversity and composition of their microbial predators—and the roles these predators play in mediating fungal necromass de

YchF is a universally conserved unconventional G protein. It is known to be involved in the translation of leaderless mRNA. However, leaderless mRNA is rare in Escherichia coli under normal culture conditions, so we analyzed E. coli YchF to clarify its function in vivo. First, bioinformatics analysis was performed, and then the growth and survival of ychF mutants were investigated. The results sug

Although biologics have revolutionized psoriasis treatment, they pose a significant burden on the healthcare budget. With the wide range of biologics available and the increasing number of biosimilars, insights into the real-world cost per responder (CPR) are required. Therefore, this study aims to evaluate the real-world CPR of adalimumab, ustekinumab, IL17-and IL23-inhibitors, incorporating both

Purpose: Prolonged stress leading to sick leave is a serious health problem, and it is crucial to find ways to support recovery. The aim of this review was to synthesize the results from qualitative research about what people with stress-related disorders experience as supportive for recovery. Methods: The systematic review was designed as a qualitative meta-synthesis following the recommendations

The estimation of high resolution spectrometer Instrument Spectral Response Functions (ISRFs) is crucial because an imperfect knowledge of these functions can induce errors in the measurements. The state-of-the-art for this problem currently relies on the use of parametric models, which frequently lack flexibility to accurately model real-world ISRFs. To address this limitation, this paper propose

Fjärrvärme är en central del av det svenska energisystemet och spelar en oumbärlig roll i samhället. Om ett avbrott skulle ske så leder det så småningom till sänkta temperaturer, och sänkta temperaturer kan medföra fara för hälsa, skador på system, och andra konsekvenser som exempelvis svårigheter att upprätthålla vårdverksamheter eller att upprätthålla det svenska försvaret. Det är alltså viktigtDistrict heating is a central part of the Swedish energy system and plays an indispensable role in society. If an interruption were to occur, it would eventually lead to lower temperatures, and lower temperatures could pose a health risk, damage to systems, and other consequences such as difficulties in maintaining healthcare operations or maintaining the Swedish defense. It is therefore important

Background: Subgroups of adult-onset diabetes, namely severe autoimmune diabetes (SAID), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), and mild obesity-related diabetes (MOD) or mild age-related (MARD) diabetes, have been defined with clinical variables and a machine-learning approach. Our aim was to describe their long-term outcomes and mortality. Methods: In

I ett samhälle där kraven på prestation ökar snabbt aktualiseras även behovet av ökad kunskap om vilka faktorer det är som faktiskt bidrar till individers upplevda prestation. Studiens syfte var att undersöka hur faktorerna ledarskap och gruppsammanhållning är relaterade till och samverkade i relation till den individuellt upplevda prestationen, samt om det finns något skillnad i dessa samband melIn a society where performance demands are rapidly increasing, the need for greater knowledge of the factors that contribute to individuals perceived performance has become increasingly important. The aim of the present study was to examine whether the factors of leadership and group cohesion influenced and interacted in relation to individual perceived performance, whether these relationships dif

Anhedoni, minskad motivation att uppleva lust, är associerad med förändringar i belöningssystemet. Belägen i ventrala striatum utgör den bilaterala nucleus accumbens (NAcc) den centrala noden i detta nätverk, där dopamin agerar som huvudsaklig excitatorisk neurotransmitter. Studier med funktionell magnetresonanstomografi (fMRI) har visat att aktiviteten i ventrala striatum minskar under belöningsbAnhedonia, reduced motivation to experience pleasure, is associated with alterations in the circuitry of the reward system. Located in the ventral striatum, the bilateral nucleus accumbens (NAcc) is the central hub of this network where dopamine acts as the main excitatory neurotransmitter. Studies using functional magnetic resonance imaging (fMRI) found that activity in the ventral striatum is de

I denna studie utvärderades hur olika sätt att integrera AI-stöd i det kliniska arbetsflödet påverkar diagnostisk precision och tidseffektivitet. Totalt 51 yrkesverksamma inom psykisk hälsa genomförde diagnostiska bedömningar av simulerade patientfall i plattformen TalkToAlba. Deltagarna randomiserades till en av tre grupper: proaktivt stöd (AI före patientintervjun), retroaktivt stöd (AI före &amThis study investigated how AI support timing impacts clinicians’ diagnostic accuracy and efficiency during simulated psychiatric assessment using TalkToAlba, a clinical conversational AI platform. Professionals with experience in mental health (N = 51) were randomized into three conditions: control/delayed (no initial AI), retroactive (AI post-interview), or proactive (AI pre- and post-interview)

Syftet med denna studie var att undersöka sambandet mellan existentiell hälsa och generell psykisk hälsa. Detta gjordes specifikt genom att jämföra två grupper av individer som skattade högre och lägre på psykiskt välbefinnande och se hur de skiljer sig åt i sin upplevelse av meningsfullhet i livet. Studien inkluderade även att mäta vilka dimensioner av meningsfullhet i livet som bidrar mest The aim of this study was to examine the relationship between existential health and general mental health, specifically to investigate how individuals with higher and lower levels of mental well-being differ in their Purpose in Life and to measure which dimensions of Purpose in Life contribute the most strongly to mental well-being. Grounded in Frankl’s existential theories, this study used

Syftet med studien var att undersöka om det fanns ett samband mellan upplevd stress och arbetsminnet hos studenter på Lunds universitet samt om det fanns tydliga könsskillnader i den upplevda stressen. Studien var utformad med en inomgruppsdesign och genomfördes online via ett webbaserat enkätformulär som mätte upplevd stress och ett arbetsminnestest. Standardiserade mått användes för stress, PercThe present study investigates the relation between perceived stress and working among university students at Lund University and if there are any clear gender differences in perceived stress. The study was designed with a within-group design and was conducted online via a web-based questionnaire that measured perceived stress and a working memory test. Standardized measures were used for stress,

Bakgrund: Förlossningsrädsla är ett tillstånd som kan påverka gravidas upplevelse av graviditet och förlossning negativt. Vid svårare förlossningsrädsla kan hjälp fås på specialiserade mottagningar för förlossningsrädsla, där bland annat barnmorskor arbetar. Dock saknas studier med fokus på barnmorskors erfarenheter av att ge stöd på specialiserade mottagningar. Syfte: Att belysa barnmorskors erfa