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The purpose of this study was to examine the effect of exacerbations on mild to moderate asthmatic patients' preference-based, health-related, quality of life scores and also to describe the effect of these exacerbations on daily life. In a survey, 100 mild to moderate asthmatic patients in the United Kingdom were asked to rate three different health marker states on a scale between 0 (death) and
Global error bounds are derived for multistep time discretizations of fully nonlinear evolution equations on infinite dimensional spaces. In contrast to earlier studies, the analysis presented here is not based on linearization procedures but on the fully nonlinear framework of logarithmic Lipschitz constants and nonlinear semigroups. The error bounds reveal how the contractive or dissipative beha
We present a logic which we call Hybrid Duration Calculus (HDC). HDC is obtained by adding the following hybrid logical machinery to the Restricted Duration Calculus (RDC): nominals, satisfaction operators, down-arrow binder, and the global modality. RDC is known to be decidable, and in this paper we show that decidability is retained when adding the hybrid logical machinery. Decidability of HDC i
Dispersion of electromagnetic waves is usually described in terms of an integrodifferential equation. We show that whenever a differential operator can be found that annihilates the susceptibility kernel of the medium, dispersion can be modeled by a partial differential equation without nonlocal operators
There is an increasing interest in new strategies for replacing animal tests in research. The use of cell cultures and integrated electrodes is seen as a promising alternative that could potentially solve this problem. In this work, we present a L-glutamate sensor based on a bienzyme redox hydrogel, capable of detecting the release of this excitatory neurotransmitter from adherently growing cells
beta-Alanine synthase catalyzes the last step in the reductive degradation pathway for uracil and thymine, which represents the main clearance route for the widely used anticancer drug 5-fluorouracil. Crystals of the recombinant enzyme from Drosophila melanogaster, which is closely related to the human enzyme, were obtained by the hanging-drop vapour-diffusion method. They diffracted to 3.3 angstr
Object. Subarachnoid hemorrhage (SAH) results in the expression of inflammatory and extracellular matrix (ECM)related genes and various G protein-coupled receptors. In the present study, the authors evaluated the time course and sequence of the transduction pathways, p38 mitogen-activated protein kinase (MAPK) and extracellular signal-regulated kinase-1 and 2 (ERK1/2), and associated transcription
OBJECTIVE: To compare costs of transurethral prostatic resection (TURP) and transurethral microwave thermotherapy (TUMT) for symptomatic benign prostatic hyperplasia (BPH) in a randomized, controlled trial. METHODS: In 70 BPH patients all costs were calculated for management, including complications and repeat treatment, during TURP or TUMT and 24-month follow-up. Clinical outcome was judged from
Addressing unsustainable consumption patterns is an important target for fulfilling the goals set in, among others, Agenda 21 and the United Nations Framework Convention on Climate Change. Gender differences in consumption patterns and their environmental impact have so far been poorly investigated. Gender differences in travelling patterns in Sweden are explored using data from the National Trav
Abstract in Spanish Inger Enkvist, catedrática de español de la Universidad de Lund, Suecia, trabajó durante tres años en un proyecto de investigación junto con Ángel Sahuquillo, de la Universidad de Sodertorn, también en Suecia, en un proyecto titulado ”Identidad e ideología en la literatura hispánica: un estudio basado en la obra de Juan Goytisolo”. El presente artículo demuestra que el resultad“Ethics and aesthetics in literary research” summaries the main findings in a three-year project on the work of the controversial Spanish writer Juan Goytisolo. The most astonishing result was the realization about the temptations and limitations of literary research: many researchers do not have sufficient knowledge about Goytisolo’s work to be able to formulate a stand; others do not want to cri
Different suggestions for the mechanism governing the narrow stability of the L(3) (sponge) phase have led to a series of debates in recent years. There have been several models developed to describe such a mechanism via thermodynamics. To date, experimental data are insufficient to test present theories. In this study, we revisit the sponge phase with two series of thermodynamic data performed on
Popular Abstract in Swedish Delaktighet i biståndsbedömning av äldre personer inför kommunalt bistånd. Äldre personers, familjemedlemmars och biståndsbedömares upplevelser. Den äldre generationen förväntas snabbt öka i Sverige och i övriga Europa under de kommande årtiondena. De äldres vårdbehov kommer att öka och därmed förväntas svårigheter att ombesörja tillräcklig kommunal vård och omsorg. ÅlAim: The overall aim of this thesis was to illuminate older persons' experience of becoming in need of public home help and their family members' experience of this situation. Further, the aim was to illuminate experiences of participation in the needs assessment process of older people and influence on decisions about public home help from the perspective of older needs-assessed persons, their fa
We consider all two times iterated Ito integrals obtained by pairing m independent standard Brownian motions. First we calculate the conditional joint characteristic function of these integrals, given the Brownian increments over the integration interval, and show that it has a form entirely similar to what is obtained in the univariate case. Then we propose an algorithm for the simultaneous simul
Rotational coherent anti-Stokes Raman spectroscopy (CARS) has since the beginning of the 1980s been developed as a non-intrusive tool for temperature measurements in combustion. Since the introduction of the dual-broadband concept in 1986, the quality of the technique has been much improved, and application to practical combustion situations facilitated. Since the first demonstration of its use in
