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Reevaluation of the role of HDL in the anticoagulant activated protein C system in humans.

HDL has anti-atherogenic properties, and plasma levels of HDL cholesterol correlate inversely with risk of coronary artery disease. HDL reportedly functions as a cofactor to the anticoagulant activated protein C (APC) in the degradation of factor Va (FVa). The aim of the present study was to elucidate the mechanism by which HDL functions as cofactor to APC. Consistent with a previous report, HDL i

Incidence, prevalence and clinical characteristics of Behcet's disease in southern Sweden.

Objective: To study the incidence, prevalence and clinical characteristics of Behçet's disease (BD) in a defined population in southern Sweden. Methods: The study area consists of three health-care districts with an adult population (≥15 years) of 809 317 on 1 January 2011 (25% of non-Swedish ancestry), situated in Skåne, the southernmost county in Sweden. Patients were identified using clinical

Malthusian Progress

Popular Abstract in English The dissertation offers two key contributions. The first is a theoretical demonstration that, even though a Malthusian society is inherently stagnant in the sense that sustained economic growth is absent, scattered advances in technology can permanently raise the long-term wage rate. The key reason why new technology can have a short-term as well as a long-term (i.e. peSome scholars maintain that pre-industrial England was held in a Malthusian ‘trap’, and that this trap prevented the sustained growth of real wages until as late as 1800. Opponents to this view argue that the structural transformations occurring in preindustrial England – urbanization, labour reallocation between sectors, and human capital investments – are features of development that are incompa

Rac1 regulates pancreatic islet morphogenesis.

BACKGROUND: Pancreatic islets of Langerhans originate from endocrine progenitors within the pancreatic ductal epithelium. Concomitant with differentiation of these progenitors into hormone-producing cells such cells delaminate, aggregate and migrate away from the ductal epithelium. The cellular and molecular mechanisms regulating islet cell delamination and cell migration are poorly understood. Ex

An investigation of serum concentration of apoM as a potential MODY3 marker using a novel ELISA.

Abstract. Cervin C, Axler O, Holmkvist J, Almgren P, Rantala E, Tuomi T, Groop L, Dahlbäck B, Karlsson E (Lund University, Malmö, Sweden, Steno Diabetes Center, Gentofte, Denmark, University of Helsinki; and Folkhälsan Research Centre, Helsinki, Finland). An investigation of serum concentration of apoM as a potential MODY3 marker using a novel ELISA. J Intern Med 2009; doi: 10.1111/j.1365-2796.200

Hässleberga – a Late Palaeolithic kill site in Scania, Sweden, confirmed by analysis of bone modifications

Late glacial skeletal remains from mainly reindeer and wild horse, but also other species such as mountain hare, arctic fox and elk have been collected from kettle holes in Hässleberga, Scania. Bones from reindeer and wild horse have been radiocarbon dated to Allerød and Younger Dryas. Analysis of bone modifications has revealed several different actors and factors behind the accumulation of the s

Film Workshops as Polyvocal Public Spheres: Minor Cinemas in Sweden

Film workshop culture is a neglected phenomenon in film history and research.This essay arguments that the film workshops that flourished in the 1960s, 70s and the 80s, often constituted public spheres in the sense of Habermas, Negt and Kluge. Focusing on the Swedish Film Workshop, Filmverkstan (1973-2001), the essay shows that films at the workshops were made because they were in resonance with t

The effects of platelet transfusions evaluated using rotational thromboelastometry.

BACKGROUND: In this study, we assessed the immediate effects of platelet transfusion on whole blood coagulation. METHODS: Ten thrombocytopenic patients given a single unit platelet transfusion of 200-300 x 10(9) platelets had their coagulation status assessed before and immediately after transfusion using rotational thromboelastometry. RESULTS: Transfusion increased the median platelet count from

Frequency of MELAS main mutation in a phenotype-targeted young ischemic stroke patient population.

Mitochondrial diseases, predominantly mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), may occasionally underlie or coincide with ischemic stroke (IS) in young and middle-aged individuals. We searched for undiagnosed patients with MELAS in a target subpopulation of unselected young IS patients enrolled in the Stroke in Young Fabry Patients study (sifap1). Among t