Investigating the effect of Aβ overexpression on tau phosphorylation
The breakdown of neuronal networks and synaptic degeneration are responsible for the memory impairment associated to Alzheimer’s disease (AD). Amyloid-β (Aβ) and tau are the two proteins that have been identified as the hallmarks for pathological changes found in the brain of Alzheimer’s patients. These two hallmarks have been extensively studied separately, but how they relate to each other and t